DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CD200 and syg-1

DIOPT Version :9

Sequence 1:	NP_001004196.2	Gene:	CD200 / 4345	HGNCID:	7203	Length:	294	Species:	Homo sapiens
Sequence 2:	NP_001123159.1	Gene:	syg-1 / 180555	WormBaseID:	WBGene00006365	Length:	730	Species:	Caenorhabditis elegans

Alignment Length:	184	Identity:	43/184 - (23%)
Similarity:	67/184 - (36%)	Gaps:	55/184 - (29%)

- Green bases have known domain annotations that are detailed below.

Human   115 YKDKINITQLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTV-YVQPIVSLHY--KF 176
            ||....:.:.|   .|:||..:.:||....:....|...|...|:..|.| :...|:|...  :.
Worm   307 YKGNQKLRETG---DTLTFETLKMEDHNRDIFCEATNEIGTTRGSIKLNVAFGARIMSTSQDKEV 368

Human   177 SE-DHLNITCSATARPAPMVFW--------------------KVPRSGIENSTVT--------LS 212
            :| |:....|:..|.|||.:||                    :..:.|..|.|.|        ||
Worm   369 NEGDNAFFHCATLANPAPAIFWTRGDSDEIIGHGENLTLENVRTWQQGNYNCTATVEGFRKQILS 433

Human   213 HPNGTTSVTSILHIKDP-----KNQV------GKEVICQVLHLGTVTDFKQTVN 255
            |         .|||:.|     |::|      ..|:||::.......:.:.|||
Worm   434 H---------YLHIRGPPTVSMKDEVSASLDEATEIICEISGRPKTNNVRWTVN 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CD200	NP_001004196.2	Ig1_MRC-OX-2_like	69..165	CDD:143254	13/50 (26%)
CD200	NP_001004196.2	Ig	<181..253	CDD:299845	23/110 (21%)
syg-1	NP_001123159.1	I-set	24..124	CDD:254352
		Ig	30..124	CDD:299845
		Ig	<151..265	CDD:299845
		Ig_2	276..353	CDD:290606	12/48 (25%)
		IG_like	283..353	CDD:214653	12/48 (25%)
		IG_like	363..427	CDD:214653	13/63 (21%)
		Ig_2	368..438	CDD:290606	17/78 (22%)
		Ig	440..528	CDD:299845	9/39 (23%)
		IG_like	450..535	CDD:214653	7/29 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910