DRSC/TRiP Functional Genomics Resources

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Protein Alignment CD200 and Cd200

DIOPT Version :10

Sequence 1:NP_001004196.2 Gene:CD200 / 4345 HGNCID:7203 Length:294 Species:Homo sapiens
Sequence 2:NP_034948.3 Gene:Cd200 / 17470 MGIID:1196990 Length:278 Species:Mus musculus


Alignment Length:263 Identity:204/263 - (77%)
Similarity:232/263 - (88%) Gaps:0/263 - (0%)


- Green bases have known domain annotations that are detailed below.


Human    30 VIRMPFSHLSTYSLVWVMAAVVLCTAQVQVVTQDEREQLYTPASLKCSLQNAQEALIVTWQKKKA 94
            |.|.||.|||||||:|.||||.|.||||:|||||||:.|:|.|||:|||:.:||.||||||||||
Mouse     5 VFRRPFCHLSTYSLIWGMAAVALSTAQVEVVTQDERKALHTTASLRCSLKTSQEPLIVTWQKKKA 69

Human    95 VSPENMVTFSENHGVVIQPAYKDKINITQLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGT 159
            ||||||||:|:.|||||||||||:||:|:|||.||:|||||.||||||||||||||||..|:|||
Mouse    70 VSPENMVTYSKTHGVVIQPAYKDRINVTELGLWNSSITFWNTTLEDEGCYMCLFNTFGSQKVSGT 134

Human   160 ACLTVYVQPIVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSIL 224
            ||||:||||||.|||.:.||||||||||||||||.:.||...:||||||.:..|.||||||||||
Mouse   135 ACLTLYVQPIVHLHYNYFEDHLNITCSATARPAPAISWKGTGTGIENSTESHFHSNGTTSVTSIL 199

Human   225 HIKDPKNQVGKEVICQVLHLGTVTDFKQTVNKGYWFSVPLLLSIVSLVILLVLISILLYWKRHRN 289
            .:||||.|||||||||||:||.|.|:||:::||:|||||||||||||||||:|||||||||||||
Mouse   200 RVKDPKTQVGKEVICQVLYLGNVIDYKQSLDKGFWFSVPLLLSIVSLVILLILISILLYWKRHRN 264

Human   290 QDR 292
            |:|
Mouse   265 QER 267

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CD200NP_001004196.2 IgV_1_MRC-OX-2_like 57..164 CDD:409433 84/106 (79%)
FR1 57..77 CDD:409433 13/19 (68%)
Ig strand A 57..61 CDD:409433 2/3 (67%)
Ig strand A' 63..67 CDD:409433 3/3 (100%)
Ig strand B 70..78 CDD:409433 5/7 (71%)
CDR1 78..84 CDD:409433 2/5 (40%)
FR2 85..94 CDD:409433 8/8 (100%)
Ig strand C 86..92 CDD:409433 5/5 (100%)
CDR2 95..112 CDD:409433 13/16 (81%)
Ig strand C' 95..103 CDD:409433 7/7 (100%)
Ig strand C' 108..112 CDD:409433 3/3 (100%)
FR3 118..148 CDD:409433 23/29 (79%)
Ig strand D 118..125 CDD:409433 3/6 (50%)
Ig strand E 128..134 CDD:409433 4/5 (80%)
Ig strand F 142..149 CDD:409433 6/6 (100%)
CDR3 149..155 CDD:409433 4/5 (80%)
Ig strand G 155..164 CDD:409433 7/8 (88%)
FR4 156..164 CDD:409433 6/7 (86%)
Ig <184..255 CDD:472250 50/70 (71%)
Ig strand C 194..198 CDD:409353 0/3 (0%)
Ig strand E 222..226 CDD:409353 3/3 (100%)
Ig strand F 236..241 CDD:409353 4/4 (100%)
Ig strand G 251..254 CDD:409353 2/2 (100%)
Cd200NP_034948.3 IgV_1_MRC-OX-2_like 32..139 CDD:409433 84/106 (79%)
FR1 32..52 CDD:409433 13/19 (68%)
Ig strand A 32..36 CDD:409433 2/3 (67%)
Ig strand A' 38..42 CDD:409433 3/3 (100%)
Ig strand B 45..53 CDD:409433 5/7 (71%)
CDR1 53..59 CDD:409433 2/5 (40%)
FR2 60..69 CDD:409433 8/8 (100%)
Ig strand C 61..67 CDD:409433 5/5 (100%)
CDR2 70..87 CDD:409433 13/16 (81%)
Ig strand C' 70..78 CDD:409433 7/7 (100%)
Ig strand C' 83..87 CDD:409433 3/3 (100%)
FR3 93..123 CDD:409433 23/29 (79%)
Ig strand D 93..100 CDD:409433 3/6 (50%)
Ig strand E 103..109 CDD:409433 4/5 (80%)
Ig strand F 117..124 CDD:409433 6/6 (100%)
CDR3 124..130 CDD:409433 4/5 (80%)
Ig strand G 130..139 CDD:409433 7/8 (88%)
FR4 131..139 CDD:409433 6/7 (86%)
ig 143..229 CDD:395002 62/85 (73%)
Ig strand C 169..173 CDD:409500 0/3 (0%)
Ig strand E 197..201 CDD:409500 3/3 (100%)
Ig strand F 211..216 CDD:409500 4/4 (100%)

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