DRSC/TRiP Functional Genomics Resources

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Protein Alignment CD200 and LOC116408739

DIOPT Version :9

Sequence 1:NP_001004196.2 Gene:CD200 / 4345 HGNCID:7203 Length:294 Species:Homo sapiens
Sequence 2:XP_031752324.1 Gene:LOC116408739 / 116408739 -ID:- Length:368 Species:Xenopus tropicalis


Alignment Length:283 Identity:79/283 - (27%)
Similarity:129/283 - (45%) Gaps:13/283 - (4%)


- Green bases have known domain annotations that are detailed below.


Human     9 TIGGPLLTATLLGKTTIND---YQVIRMPFSHLSTYSLVWVMAAVVLCTAQVQVVTQDEREQLYT 70
            |:.|...||..:..|..:|   |..|...|:..|...:.::....|| |.:.:.|      :|..
 Frog    95 TVLGLKETAITVWNTQADDEGMYPCIFNIFAVGSVKGITYISFGDVL-TEKSKAV------RLGE 152

Human    71 PASLKCSLQNAQEALIVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGLQNSTITFWN 135
            ..||||.|:...|...||||:......:|:..| ...||.:...|::::..:.|.|..:.|..|.
 Frog   153 SLSLKCVLRKPVEVTQVTWQRTVKDKQDNVAIF-RKEGVEVMDTYRNRLRFSSLDLNVTEIIVWK 216

Human   136 ITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHLNITCSATARPAPMVFWKVP 200
            :...|||.|.|||||...|.:||...:.||.....::..|......|:||.||..|.|...|...
 Frog   217 VQAGDEGAYRCLFNTSMSGTLSGETSIYVYEPLNANMEVKSLNGRTNVTCLATGYPQPNTTWNGV 281

Human   201 RSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLHLGTVTDFKQTVNKGYWFSVPLL 265
            ..|..|.:...:| .|..:|.|.:.:...:::|.:::.|:|.:......||..| |.|..:..::
 Frog   282 GEGNLNGSKLETH-GGIVTVKSWIVVNATESEVREKLECRVQNGEKPRIFKIPV-KSYPQTTIVV 344

Human   266 LSIVSLVILLVLISILLYWKRHR 288
            |.:|.||::|.|:.::...|:.|
 Frog   345 LIVVLLVLVLALVLVICRAKKRR 367

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CD200NP_001004196.2 Ig1_MRC-OX-2_like 69..165 CDD:143254 31/95 (33%)
Ig <181..253 CDD:299845 19/71 (27%)
LOC116408739XP_031752324.1 Ig 31..131 CDD:416386 10/35 (29%)
FR1 31..50 CDD:409353
Ig strand A 31..34 CDD:409353
Ig strand A' 36..40 CDD:409353
Ig strand B 43..51 CDD:409353
CDR1 51..57 CDD:409353
FR2 58..67 CDD:409353
Ig strand C 59..65 CDD:409353
CDR2 68..85 CDD:409353
Ig strand C' 68..76 CDD:409353
Ig strand C' 81..85 CDD:409353
FR3 91..121 CDD:409353 7/25 (28%)
Ig strand D 91..98 CDD:409353 1/2 (50%)
Ig strand E 101..107 CDD:409353 2/5 (40%)
Ig strand F 115..122 CDD:409353 2/6 (33%)
CDR3 122..128 CDD:409353 1/5 (20%)
Ig 140..241 CDD:416386 36/108 (33%)
FR1 140..159 CDD:409353 8/25 (32%)
Ig strand A 140..143 CDD:409353 2/3 (67%)
Ig strand A' 145..149 CDD:409353 1/9 (11%)
Ig strand B 152..160 CDD:409353 4/7 (57%)
CDR1 160..166 CDD:409353 1/5 (20%)
FR2 167..176 CDD:409353 4/8 (50%)
Ig strand C 168..174 CDD:409353 4/5 (80%)
CDR2 177..193 CDD:409353 4/16 (25%)
Ig strand C' 177..185 CDD:409353 1/7 (14%)
Ig strand C' 189..193 CDD:409353 2/3 (67%)
FR3 199..229 CDD:409353 9/29 (31%)
Ig strand D 199..206 CDD:409353 0/6 (0%)
Ig strand E 209..215 CDD:409353 1/5 (20%)
Ig strand F 223..230 CDD:409353 4/6 (67%)
CDR3 230..236 CDD:409353 2/5 (40%)
Ig <264..324 CDD:416386 16/60 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 63 1.000 Domainoid score I37573
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 99 1.000 Inparanoid score I13146
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0013977
OrthoInspector 1 1.000 - - oto153433
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X7609
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
55.050

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