Protein Alignment Rpn2 and Rpn1

DIOPT Version :9

• Sequence 1: NP_001263057.1
• Gene: Rpn2 / 43449
• FlyBaseID: FBgn0028692
• Length: 1029
• Species: Drosophila melanogaster
• Sequence 2: NP_649158.1
• Gene: Rpn1 / 40174
• FlyBaseID: FBgn0028695
• Length: 919
• Species: Drosophila melanogaster
• Alignment Length: 999
• Identity: 198/999 - (19%)
• Similarity: 340/999 - (34%)
• Gaps: 325/999 - (32%)

  Fly    26 KKLDNIVDEFWPEISES----IEKIEMLHEDRSFPENKL--------AGMVASK----------- 67
            :|.|....|..||:|:.    .|::|:|.:....|:.||        |.::.:.
  Fly    30 EKKDGKDKEQQPELSDEDQQLQEELELLVQHLQEPDAKLYQPTLESMAKLIRASTTSMTSVPKPL 94

  Fly    68 ------------VFYH--------------------LGSFEDALTYALGAGDLFDVNAR-----N 95
                        |:.|                    :||.:|.|.|..    |.|...|     :
  Fly    95 KFMRPHYETMKTVYKHMPNEQARQLCADIISVLSMTMGSGKDCLAYRF----LCDRKQRIGDWGH 155

  Fly    96 EYTETIIAKCI--------DFYIAQRVEFIENPKEASVVDERLEGIVNRMIQRCLDDNQFRQALG 152
            ||...:..:..        ||    ||:.||              :|.::|...::.|....|..
  Fly   156 EYVRHLSGEISAHYHDTTGDF----RVQLIE--------------LVKQIIPYNMEHNAEADACD 202

  Fly   153 IALETRRMDTFKDAIMKSDDVRGML----AYAYNVTMSLIQNRGFRNEVLRCLVSLYRDLGVPDY 213
            :.:|...:....|.:.:|...|..|    .|.|                            |||.
  Fly   203 LLIEIDHLHLLSDFVDESAYPRVCLYLQSCYPY----------------------------VPDP 239

  Fly   214 VNMCQCLIFLEDPFAVAEMLDNLTRSSVETNNLMAYQIAFDLYESATQEFLGNVLQHLKNTAPIP 278
            .|    .|.||....::...:..|:         |.::|..|.:   .:.:|.:.:..|..| :.
  Fly   240 DN----TIILETALQLSRKFNQYTQ---------AMRLALMLND---MDKIGEIFKEPKEPA-MQ 287

  Fly   279 TALPSTFKPQGTTSEDGAKSEGDKSKSDEDITEETPADDKVERTIDSLNEVEKLHQKNIEKLISI 343
            ..|......|....|               :.|..|..|.:...:.:.| :.| |..|:.:.:.|
  Fly   288 KQLAFMLARQQICLE---------------LDELVPDYDDLMEIMSNAN-LNK-HFLNLARELDI 335

  Fly   344 LSGEVSIDLQLQFL--IRSNHADLQVLRGTKEAVRVSICHTATVIANAFMHSGTTSDQFL-RDNL 405
            :..:...|:....|  .||..|.:||     ::.:.::   |....|.|:::|...|:.| .|..
  Fly   336 MEPKTPEDIYKSHLDNSRSRFASIQV-----DSAKQNL---AASFVNGFVNAGFGVDKLLSEDGN 392

  Fly   406 DWLARATNWAKLTATASLGVIHRGHEKDSLALMQSYLPKEAGPSSGYS-----EGGALYALGLIH 465
            .||.:......|:||||||:|........|.::..||         ||     :.|||.|.|::
  Fly   393 KWLYKNKEHGMLSATASLGLILLWDVDGGLTMIDKYL---------YSTDDNIKSGALLACGIV- 447

  Fly   466 ANHG-ANIID---YLLQQLKDAQNENVRHGGCLGLGLAGMGTHRQDLYEQLK----FNLYQDDAV 522
             |.| .|.:|   .||....|.||..:|.|..||||:|..|::|..:.:.||    |......:.
  Fly   448 -NCGIRNEVDPAHALLSDYIDNQNSCMRVGAILGLGIAYAGSNRSIVIDTLKTVFSFGSNNKSSA 511

  Fly   523 TGEAAGI---AMGMVMLGSKNAQ----AIEDMVSYAQETQHEKILRGLAVGISLTMFSRLEEADP 580
            :.|..||   ::|::.:||.|::    .::.::...:....:...|.|.:|:.|....|.:..:.
  Fly   512 SVEILGITALSLGLISVGSCNSEITEILLQTIMGLTKADLKDTYTRFLFLGLGLLYLGRQKSTEA 576

  Fly   581 LVTSLSSDKDPVLRRSGMYTIAMAYNGTGSNKAIRKLLHVA-----VSDVNDDVRRA-------- 632
            ::.:|...::|....:.......||.|||:...|::|||:.     .|..:|:..::
  Fly   577 VMMTLEVLEEPYRSMATTMVDICAYAGTGNVLKIQQLLHICSDHYETSSADDEKEKSKKDKGKDK 641

  Fly   633 --------------------AVTAIGFILFRSPEQCPSVVSL-----LAESYNPHVRYGAAMALG 672
                                ::..:|..|....|...:.::.     |.....|.:|....:|||
  Fly   642 EKEKEKEKEKEREKDLSATQSIAVLGIALIAMGEDIGAEMAYRSFGNLLRYCEPAIRRAVPLALG 706

  Fly   673 IACAGTGLREAIALLEPMVKFDPVNFVRQGALIASAMILIQHTDQSCPKSTFFRQLYAEVISNKH 737
            :..|.   ...:.:::.:.||                   .|...            |||..|
  Fly   707 LISAS---NPKLNIIDTLSKF-------------------SHDSD------------AEVAHN-- 735

  Fly   738 EDVMAKYGAILAQGIIDAGGRNATLSLQSR---TGHTNLQAVVGMLAFTQYWYWFPLAH----TL 795
                    ||.|.|::.||..||.|:...|   ..|:...:.:.|:...|     .|.|    ||
  Fly   736 --------AIFAMGLVGAGTNNARLASMLRQLAQYHSKDPSNLFMVRIAQ-----SLTHLGKGTL 787

  Fly   796 SLA--------FTPTCVIGLNS------DLK--------------MPKMEYKSAAKPSLYAYPAP 832
            ||:        ..|..|.||.:      |:|              :|.|:.:     .|..:...
  Fly   788 SLSPYHSDRQLMNPMAVAGLMATLVSLLDVKNLILNRSHYLLYTLVPAMQAR-----MLITFDEE 847

  Fly   833 LEEKKSEEREKVATAVLSIAARQK 856
            |.:.:...|..:|..|:..|.:.|
  Fly   848 LNQLQVPVRVGIAIDVVGQAGKPK 871

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rpn2	NP_001263057.1	RPN2	1..1003	CDD:227446	198/999 (20%)
		PC_rep	456..489	CDD:280095	14/36 (39%)
		PC_rep	526..559	CDD:280095	6/39 (15%)
		HEAT repeat	581..602	CDD:293787	2/20 (10%)
		HEAT repeat	616..639	CDD:293787	5/55 (9%)
		HEAT repeat	651..676	CDD:293787	6/29 (21%)
		PC_rep	666..701	CDD:280095	6/34 (18%)
Rpn1	NP_649158.1	RPN1	61..919	CDD:227441	189/968 (20%)
		PC_rep	476..509	CDD:280095	11/32 (34%)
		PC_rep	735..766	CDD:280095	12/40 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468996
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10943
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940