DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pglym78 and pgam2

DIOPT Version :9

Sequence 1:	NP_001034075.1	Gene:	Pglym78 / 43447	FlyBaseID:	FBgn0014869	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_957318.1	Gene:	pgam2 / 572733	ZFINID:	ZDB-GENE-040116-6	Length:	255	Species:	Danio rerio

Alignment Length:	255	Identity:	165/255 - (64%)
Similarity:	208/255 - (81%)	Gaps:	1/255 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGGKYKIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQ 65
            |...:::|:||||||.|||:|:||||:||:|||||.|||....:|:||||::|||.:||||.||.
Zfish     1 MAAAHRLVIVRHGESSWNQENRFCGWFDADLSEKGLEEAKRGAQAIKDAGMKFDVCYTSVLKRAI 65

  Fly    66 VTLASILKASGHKEIPIQKTWRLNERHYGGLTGLNKAETAAKYGEAQVQIWRRSFDTPPPPMEPG 130
            .||.:|::.:....:|:.:|||||||||||||||||||||||:||.||:|||||||.|||||:..
Zfish    66 KTLWTIMEGTDQMWVPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDIPPPPMDKD 130

  Fly   131 HPYYENIVKDPRYAEGPKPEEFPQFESLKLTIERTLPYWNDVIIPQMKEGKRILIAAHGNSLRGI 195
            |||::.|.:..|| :|.|..|.|..||||.||.|.||:||:||:|::|.||.::|||||||||||
Zfish   131 HPYHKIISESRRY-KGLKEGELPICESLKDTIARALPFWNEVIVPEIKAGKNVIIAAHGNSLRGI 194

  Fly   196 VKHLDNLSEDAIMALNLPTGIPFVYELDENFKPVVSMQFLGDEETVKKAIEAVAAQGKAK 255
            ||||:::|:.|||.||||||||.|||||::.||:..||||||||||:||:||||||||.|
Zfish   195 VKHLESMSDAAIMELNLPTGIPIVYELDKDLKPIKPMQFLGDEETVRKAMEAVAAQGKVK 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pglym78	NP_001034075.1	HP	5..255	CDD:299704	163/249 (65%)
pgam2	NP_957318.1	gpmA	5..254	CDD:184516	163/249 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595443
Domainoid	1	1.000	183	1.000	Domainoid score	I3361
eggNOG	1	0.900	-	-		E1_COG0588
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	354	1.000	Inparanoid score	I2211
OMA	1	1.010	-	-		QHG61896
OrthoDB	1	1.010	-	-		D496634at33208
OrthoFinder	1	1.000	-	-		FOG0000615
OrthoInspector	1	1.000	-	-		mtm6585
orthoMCL	1	0.900	-	-		OOG6_101500
Panther	1	1.100	-	-	O	PTHR11931
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R933
SonicParanoid	1	1.000	-	-		X392
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800