DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pglym78 and pgam1b

DIOPT Version :9

Sequence 1:	NP_001034075.1	Gene:	Pglym78 / 43447	FlyBaseID:	FBgn0014869	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_958457.2	Gene:	pgam1b / 327165	ZFINID:	ZDB-GENE-030131-5376	Length:	254	Species:	Danio rerio

Alignment Length:	251	Identity:	168/251 - (66%)
Similarity:	206/251 - (82%)	Gaps:	1/251 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YKIVMVRHGESEWNQKNQFCGWYDANLSEKGQEEALAAGKAVKDAGLEFDVAHTSVLTRAQVTLA 69
            ||:|::|||||.|||:|:||||:||:||:.|:.||...|:|:||||.|||:.:||||.||..||.
Zfish     4 YKLVLIRHGESVWNQENRFCGWFDADLSDTGEAEAKRGGQALKDAGYEFDICYTSVLKRAIRTLW 68

  Fly    70 SILKASGHKEIPIQKTWRLNERHYGGLTGLNKAETAAKYGEAQVQIWRRSFDTPPPPMEPGHPYY 134
            .:|.......:|:.:|||||||||||||||||||||||:|||||:|||||:|.|||||:|.|.:|
Zfish    69 LVLDGIDQMWLPVHRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYDIPPPPMDPEHDFY 133

  Fly   135 ENIVKDPRYAEGPKPEEFPQFESLKLTIERTLPYWNDVIIPQMKEGKRILIAAHGNSLRGIVKHL 199
            ..|.||.||.:..: ::.|..||||.||.|.||:||:.|:||:|||||:||||||||||||||||
Zfish   134 TAISKDRRYGDLTE-DQLPSCESLKDTIARALPFWNEEIVPQIKEGKRVLIAAHGNSLRGIVKHL 197

  Fly   200 DNLSEDAIMALNLPTGIPFVYELDENFKPVVSMQFLGDEETVKKAIEAVAAQGKAK 255
            :.:||:|||.||||||||.:||||:|.|||..||||||||||:||:||||||||||
Zfish   198 EGMSEEAIMELNLPTGIPILYELDKNLKPVKPMQFLGDEETVRKAMEAVAAQGKAK 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pglym78	NP_001034075.1	HP	5..255	CDD:299704	166/249 (67%)
pgam1b	NP_958457.2	gpmA	4..253	CDD:184516	166/249 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595445
Domainoid	1	1.000	183	1.000	Domainoid score	I3361
eggNOG	1	0.900	-	-		E1_COG0588
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37647
Inparanoid	1	1.050	354	1.000	Inparanoid score	I2211
OMA	1	1.010	-	-		QHG61896
OrthoDB	1	1.010	-	-		D496634at33208
OrthoFinder	1	1.000	-	-		FOG0000615
OrthoInspector	1	1.000	-	-		mtm6585
orthoMCL	1	0.900	-	-		OOG6_101500
Panther	1	1.100	-	-	LDO	PTHR11931
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R933
SonicParanoid	1	1.000	-	-		X392
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800