DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14511 and SLC35B4

DIOPT Version :9

Sequence 1:	NP_651675.1	Gene:	CG14511 / 43445	FlyBaseID:	FBgn0039641	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_116215.1	Gene:	SLC35B4 / 84912	HGNCID:	20584	Length:	331	Species:	Homo sapiens

Alignment Length:	317	Identity:	161/317 - (50%)
Similarity:	219/317 - (69%)	Gaps:	8/317 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IRAISAICGVFLGCCSGVVFLELLVKLDPGAGNLITGAQFAFIALEGFIFTSKFGLAQRVISLRD 69
            :|...|:..||.||||.|:|||||.:..||.||::|.|||.|||:|||:|.:..|.....|.:|.
Human     1 MRPALAVGLVFAGCCSNVIFLELLARKHPGCGNIVTFAQFLFIAVEGFLFEADLGRKPPAIPIRY 65

  Fly    70 YALLVAMFFLTSVCNNYVFKFKVPMTLHMIIRGGSLISNMCLCTLILKRSYRLSQYISVLMISVG 134
            ||::|.|||..||.|||.....:.|.||||.|.||||:||.|..:|||:.|.:.:|.|:.::|||
Human    66 YAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSIFKYTSIALVSVG 130

  Fly   135 IFVCTYFSSPDLVGKMENLDSGAEADTF----WWLLGVALLVLALFVSSYMGITQELLYRRHGKC 195
            ||:||:.|:..:..:    .|.:|.|.|    |||||:..|..||.:|:.|||.||.||:|.||.
Human   131 IFICTFMSAKQVTSQ----SSLSENDGFQAFVWWLLGIGALTFALLMSARMGIFQETLYKRFGKH 191

  Fly   196 AREALYYTHLLPLPAFLLMHDDIRTHWLLAFTGESYQLPLLGVAVPLILLYLLGNVLAQHLCISS 260
            ::|||:|.|.||||.|:.:..||..|.:|....|.|::|::||.:|::..|||.|::.|::||..
Human   192 SKEALFYNHALPLPGFVFLASDIYDHAVLFNKSELYEIPVIGVTLPIMWFYLLMNIITQYVCIRG 256

  Fly   261 VYTLTTECSSLTVTLILTLRKFISLVFSIVYFRNPFTWWHWLGTALVFVGTLMFANV 317
            |:.|||||:||||||::|||||:||:|||:||:||||.||||||..||:||||:..|
Human   257 VFILTTECASLTVTLVVTLRKFVSLIFSILYFQNPFTLWHWLGTLFVFIGTLMYTEV 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14511	NP_651675.1	UAA	6..318	CDD:285625	161/316 (51%)
SLC35B4	NP_116215.1	UAA	2..314	CDD:312076	161/316 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151754
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1583
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54056
OrthoDB	1	1.010	-	-		D1209974at2759
OrthoFinder	1	1.000	-	-		FOG0004206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10778
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2952
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.820