Protein Alignment superdeath and Erap1

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_109636.1
• Gene: Erap1 / 80898
• MGIID: 1933403
• Length: 930
• Species: Mus musculus
• Alignment Length: 952
• Identity: 329/952 - (34%)
• Similarity: 515/952 - (54%)
• Gaps: 91/952 - (9%)

  Fly    90 CTSYHLRRLKAGHDDTPKYDRDVRLPHSIRPLKYNITIEPQLSGNFTFAGSVQIRIRVLEDCYNI 154
            |.:..:..|||.:.|:..:: ::|||..:.|:.|::.|...|| ..||.|..::.|........|
Mouse    20 CQNSDIESLKASNGDSFPWN-NMRLPEYMTPIHYDLMIHANLS-TLTFWGKTEVEIIASRPTSTI 82

  Fly   155 TMHAEELNISRSDASVHRVQNNGEP-EGDGLRI-----HKQYLVGAKQFFVIELYDKLLKDVEYV 213
            .||:..|.||:  |::.|  ..||. ..:.|::     |:|..:.|.|        .||....|.
Mouse    83 IMHSHHLQISK--ATLRR--GAGEMLSEEPLKVLEYPAHEQVALLAAQ--------PLLAGSLYT 135

  Fly   214 VHLRFDGIIEDYLQGFYRSSYEV-HNETRWVASTQFQATDARRAFPCFDEPALKANFTLHIAR-P 276
            |.:.:...:.:...|||:|:|.. ..|.|.:|:|||:.|.||.||||||||||||:|::.|.| |
Mouse   136 VIIDYAANLSESFHGFYKSTYRTQEGEMRILAATQFEPTAARMAFPCFDEPALKASFSIKIKRDP 200

  Fly   277 RNMTTISNMPIVSSNDHATMPSYVWDHFAESLPMSTYLVAYAISDFTHIS----SG-NFAVWARA 336
            |:: .|||||:|.|.:.|  ...:.|||..::.|||||||:.||||..:|    || ..:|:|..
Mouse   201 RHL-AISNMPLVKSVNVA--EGLIEDHFDITVKMSTYLVAFIISDFKSVSKMTKSGVKVSVYAVP 262

  Fly   337 DAIKSAEYALSVGPRILTFLQDFFNVTFPLPKIDMIALPEFQAGAMENWGLITFRETAMLYDPGV 401
            |.|..|:|||.....:|.|.:|:||:.:||||.|:.|:|:||:||||||||.|:||:::|||...
Mouse   263 DKINQADYALDAAVTLLEFYEDYFNIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESSLLYDKEK 327

  Fly   402 ATANNKQRVASVVGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADAVAPEWKQLDQFVVN 466
            ::|::|..:..:|.|||||||||||||..||:|:|||||||.:||:::.....||.|..|.|...
Mouse   328 SSASSKLGITMIVSHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVTVTHPELKVEDYFFGK 392

  Fly   467 ELQAVFQLDALSTSHKISHEVFNPQEISEIFDRISYAKGSTIIRMMAHFLTNPIFRRGLSKYLQE 531
            ...|: ::|||::||.:|..|.||.:|.|:||.:||.||:.|:.|:..:|:...|:||:.:|||:
Mouse   393 CFNAM-EVDALNSSHPVSTPVENPAQIREMFDDVSYEKGACILNMLRDYLSADTFKRGIVQYLQK 456

  Fly   532 MAYNSATQDDLWHFLTVEAKSSG--LLDD--SRS---------------VKEIMDTWTLQTGYPV 577
            .:|.:...:|||:.:.....:.|  .:|.  |||               ||.:|:|||||.|:|:
Mouse   457 YSYKNTKNEDLWNSMMHICPTDGTQTMDGFCSRSQHSSSTSHWRQEVVDVKTMMNTWTLQKGFPL 521

  Fly   578 VKVSRHPNSDVIRLEQVRFVYTNTTREDESLLWYIPITFTT---DSELNFANTRPTTWMPRTKLY 639
            :.::....:  :.::|..::..:....:...||::|:||.|   ||...|        :.:||..
Mouse   522 ITITVSGRN--VHMKQEHYMKGSERFPETGYLWHVPLTFITSKSDSVQRF--------LLKTKTD 576

  Fly   640 ELENRELSLAKWFIFNVQQTGYYRVNYDLENWMAITEHLMDVDNFEDIAPANRAQLIDDVMNLAR 704
            .|...|  ..:|..|||...|||.|:|..:.|.:::..|.:...  .|:..:||.||::...|..
Mouse   577 VLILPE--AVQWIKFNVGMNGYYIVHYADDGWASLSGLLKEAHT--TISSNDRASLINNAFQLVS 637

  Fly   705 GSYLSYETAMNLTRYLGHELGHVPWKAAISNFIFIDSMFVNSGDYDLL------KNYLLKQLKKV 763
            ...||.|.|::||.||.:|...:|...|::..|   .|:......|::      |::|||.||.:
Mouse   638 IEKLSIEKALDLTLYLKNETEIMPIFQALNELI---PMYKLMEKRDMIEVETQFKDFLLKLLKDL 699

  Fly   764 YDQVGFKDSQDESEDILVKLKRADILSMACHLGHQECIAEASRHFQNWMQTPNPDSNNPIVPNLR 828
            .|:..:.|....||.:|    |:.:|.:||...:|.|:..|.|:|:.| ::.|.:.:.||...|
Mouse   700 IDKQTWTDEGSVSERML----RSQLLLLACVRNYQPCVQRAERYFREW-KSSNGNMSIPIDVTL- 758

  Fly   829 GVVYCSAIQYGTEYEWDFAFERFLKTNVPGEKDLLLNALGCSKEPWLLYRFLRRGISGQHIRKQD 893
             .|:....| .|| .|||.:.::..:....||..:..:|..||:|..|...|.:...|:.|:.|:
Mouse   759 -AVFAVGAQ-NTE-GWDFLYSKYQSSLSSTEKSQIEFSLCTSKDPEKLQWLLDQSFKGEIIKTQE 820

  Fly   894 LFRVFAAVSTTVVGQNIAFDFLRNNWQEI--KTYMGSQMSSIHTLFKFATKGFNSKFQLGEFENF 956
            ...:...:....||..:|:.|||.||.::  |..:||  |||..:....|..|:::.:|.|.:.|
Mouse   821 FPHILTLIGRNPVGYPLAWKFLRENWNKLVQKFELGS--SSIAHMVMGTTDQFSTRARLEEVKGF 883

  Fly   957 VKD--AHWDYDRPVQQIVEHIETSVDWMNKNYKSIVRWLENE 996
            ...  .:....|.|||.:|.||.::.||:||:..|..||:.|
Mouse   884 FSSLKENGSQLRCVQQTIETIEENIRWMDKNFDKIRLWLQKE 925

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	193/481 (40%)
		ERAP1_C	651..976	CDD:463368	98/334 (29%)
Erap1	NP_109636.1	M1_APN-Q_like	50..515	CDD:341064	193/481 (40%)
		ERAP1_C	586..905	CDD:463368	98/334 (29%)