Protein Alignment CG14516 and CG4467

DIOPT Version :9

• Sequence 1: NP_651674.3
• Gene: CG14516 / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Alignment Length: 1179
• Identity: 277/1179 - (23%)
• Similarity: 471/1179 - (39%)
• Gaps: 276/1179 - (23%)

  Fly    22 NMESRPMNAAT------------------------PTTTTTF---SKGGR--RYSVSLTT---AI 54
            ||..|....||                        .|...||   |.|||  |..|::.:   |:
  Fly    10 NMSKRDYKVATTDGIELEPLGGEKCDKDKDKDKEKQTNGVTFGGESSGGRQTRTGVAVCSQRRAL 74

  Fly    55 LLASFFICTLLAVGFIV-----YNFATCAE-----LEPDSDEDVVCTSYHLRRLKAGHDDTPKYD 109
            |:|...:.:||....|:     .|..:|..     .|.|.:.:    :.....:....:..|..:
  Fly    75 LVAGIVLGSLLLTAIIIAYAGPQNDCSCGSKTVSGYETDEENN----TQPFNPIATNGEPFPWLE 135

  Fly   110 RDVRLPHSIRPLKYNITIEPQLSGNFTFAGSVQIRIRVLEDCYNITMHAEELNISRSDASVHRVQ 174
            :  .||.|:|||:|.:||.|.|: .....|.|.|.:.|.::...|.:|.::||::..     .:.
  Fly   136 K--MLPTSVRPLRYMVTIHPNLT-TLDVKGQVTIDLHVEKETNFIVLHIQDLNVTEK-----AIV 192

  Fly   175 NNGEPEGDGLRIHKQYLVGAKQFFVIELYDKLLKDVEYVVHLRFDGIIEDYLQGFYRSSYEVHNE 239
            ..| |:|..|:|.|......:|...||:.::|.|...|.::||:...:....:|||...||..|.
  Fly   193 TPG-PKGYALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQYESSNG 256

  Fly   240 T-RWVASTQFQATDARRAFPCFDEPALKANFTLHIARPRNMTTISNMPIVSSNDHATMPSYVW-- 301
            . |.:|:|.|:...|||||||||||.::|.|.:.:.|.|....:||..:.::.|   :..|:.
  Fly   257 VERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTTED---VGFYMGTG 318

  Fly   302 ---DHFAESLPMSTYLVAYAISDF----------------------------------------- 322
               |.|.|:.|:....||:.:|||
  Fly   319 LLRDDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGKN 383

  Fly   323 ---------THI----------------------------------------SSG-------NFA 331
                     ||.                                        |:|       ::.
  Fly   384 PPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRAPSYT 448

  Fly   332 VWARADAIKSAEYALSVGPRILTFLQDFFNVTFPLPKIDMIALPEFQAGAMENWGLITFRETAML 396
            .:|..|.:..:.:.|.....:|.:||.:.::::||.|:|.:|||......:.:.||:|.: |:.|
  Fly   449 FYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLK-TSFL 512

  Fly   397 YDPGVATANNKQRVASVVGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADAVAP---EWK 458
            .||...|:...|..|..:...:..|:||.:.:.....|:||.||.   ::||...|:||   .|.
  Fly   513 TDPSSITSEQYQFSALRIAEAMVRQFFGGITSRKVLKDVWLWEGL---IQYLGIHALAPLQETWP 574

  Fly   459 QLDQFVVNELQAVFQLDAL--------STSHKISHEVFNPQEISEIFDRISYAKGSTIIRMMAHF 515
            ..:.:::....|...:||:        .|||..::|.|..|:.:.||..:..|.|
  Fly   575 LREMYLLKMATAALDIDAIQGWDSIMNGTSHDGNNEEFFVQKTAAIFSMLHTAIG---------- 629

  Fly   516 LTNPIFRRGLSKYLQEMAYNSATQDDLWHFLTVEAKSSGLLDDSRSVKEIMDTWTLQTGYPVVKV 580
              ...||..|..:|:...:.:|...|||...|.:|      :.|:::|::|..||.|.|:|::.|
  Fly   630 --EDRFRGCLGSFLKVNRFRTAEPTDLWTICTKKA------NGSKNIKDMMTLWTHQPGFPLLTV 686

  Fly   581 SRHPNSDVIRLEQVRF----------------VYTNTT-------------------REDESLLW 610
            ::..||  |.:.|..|                .|..||                   :....:.|
  Fly   687 TKMGNS--ISISQRPFRPAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQGSKHKVAPHMKW 749

  Fly   611 YIPITFTTDSELNFANTRPTTWMPRTKLYELENRELSL-----AKWFIFNVQQTGYYRVNYDLEN 670
            ..|:|:.||  :|  |...|.||        :|.:::.     .||...|..|.|||||.|:.:|
  Fly   750 IFPVTYVTD--IN--NVSETLWM--------QNVDVTFNVPENVKWIKVNAIQNGYYRVVYNDDN 802

  Fly   671 WMAITEHLMDVDNFEDIAPANRAQLIDDVMNLARGSYLSYETAMNLTRYLGHELGHVPWKAAISN 735
            |.::.|.|  ..|.......:|..::.|...|...:.|..|..||:.:||..|..:.|...|:.:
  Fly   803 WASLIEEL--AANPNRFTSEDRLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMALALRH 865

  Fly   736 FIFIDSMFVNSGDYDLLKNYLLKQLKKVYDQVGFKDSQDESEDILVKLKRADILSMACHLGHQEC 800
            ......:...|..:.:|..::..::..|.::||:.|    ..|:..:|.|.::|..:......:.
  Fly   866 LEKWRRILKYSECFLMLSEFIKMKISTVMEKVGWSD----DGDVATRLLRPEVLLASVLWEDIDS 926

  Fly   801 IAEASRHFQNWMQTPNPDSNNPIVPNLRGVVYCSAIQYGTEYEWDFAFERFL------KTNVPGE 859
            |.:|......::..    :...|.||||.|||..:|..|....|...:|||:      :|.|  |
  Fly   927 ITKAKNMLNQYLYY----NGTAIPPNLREVVYTGSILSGEYIYWQHCWERFVNLQRTSETFV--E 985

  Fly   860 KDLLLNALGCSKEPWLLYRFLRRGISGQHIR---KQDLFRVFAAVSTTVVGQNIAFDFLRNNWQE 921
            :..||.|||.:|:.||..|.|      .|:.   .:::.:|..|::.|..|..:|..||:..|.|
  Fly   986 RMQLLRALGRTKDAWLQNRLL------SHVTMLPTEEVVQVLKAIAGTPTGGAMACRFLQAKWFE 1044

  Fly   922 IKTYMGSQMSSIHTLFKFATKGFNSKFQLGEFENFVKDAHWDYDRPV-QQIVEHIETSVDWMNKN 985
            ::..:|....|...:....|:...:||...|.::.|......:...| ...:..:.::|:|:.::
  Fly  1045 LEKRLGPGTISFAKVISAITQYGATKFDYDELKSLVHRFGRGHGMSVLNMTLSSVASNVEWVARS 1109

  Fly   986 YKSIVRWLE 994
            ..|:.:|:|
  Fly  1110 QTSLYKWVE 1118

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14516	NP_651674.3	Peptidase_M1	113..505	CDD:279741	124/505 (25%)
		M1_APN_2	121..576	CDD:189008	137/568 (24%)
		ERAP1_C	652..974	CDD:288671	82/331 (25%)
CG4467	NP_001036747.1	Peptidase_M1	138..593	CDD:279741	114/468 (24%)
		GluZincin	145..682	CDD:301352	137/568 (24%)
		ERAP1_C	784..1078	CDD:288671	80/311 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920