Protein Alignment superdeath and erap1b

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_956500.2
• Gene: erap1b / 393175
• ZFINID: ZDB-GENE-040426-934
• Length: 963
• Species: Danio rerio
• Alignment Length: 958
• Identity: 319/958 - (33%)
• Similarity: 499/958 - (52%)
• Gaps: 127/958 - (13%)

  Fly   112 VRLPHSIRPLKYNITIEPQLSGNFTFAGSVQIRIRVLEDCYNITMHAEELNISRS---DASVHRV 173
            :|||.:|.||.||:.|.|.|: :..|.|||||:|.||:|...|.:|::.|.||.:   ||::.:.
Zfish    45 MRLPDTISPLHYNLLIHPNLT-SLDFTGSVQIQIEVLQDTKTIILHSKNLQISSARLLDANIAQQ 108

  Fly   174 QNNGEPEGDGLRIHKQYLVGAKQFF--VIELYDKLL--KDVEYVVHLRFDGIIEDYLQGFYRSSY 234
            |        .|:: .:|     .:|  :..:.||.|  :...|.|.|.|...:.:...|||:|:|
Zfish   109 Q--------PLKV-LEY-----PYFQQIALVSDKALLKRGHVYSVELHFAANLSESFHGFYKSTY 159

  Fly   235 EV-HNETRWVASTQFQATDARRAFPCFDEPALKANFTLHIARPRNMTTISNMPIVSSNDHATMPS 298
            .. ..:.|.||||||:||.||.|||||||||.||||::.|.|......:||||.:.:.:  ....
Zfish   160 RTSKGDVRVVASTQFEATSARAAFPCFDEPAFKANFSVQIRREAKHIALSNMPKLRTLE--LKNG 222

  Fly   299 YVWDHFAESLPMSTYLVAYAISDFTHISSGN-----FAVWARADAIKSAEYALSVGPRILTFLQD 358
            ...|.|..|:.||||||||.:|||..||..:     .:|:|..:.|..||:||....::|.|..|
Zfish   223 LFEDQFDVSVKMSTYLVAYIVSDFLSISKTSQHGVQISVYAVPEKIDQAEFALDAAVKLLDFYDD 287

  Fly   359 FFNVTFPLPK--------------------IDMIALPEFQAGAMENWGLITFRETAMLYDPGVAT 403
            :|::.:||||                    :|:.|:|:||:||||||||.|:||:|:|:||..::
Zfish   288 YFDIPYPLPKQEKPTIKHAKEEFSVYIICFVDLAAIPDFQSGAMENWGLTTYRESALLFDPHKSS 352

  Fly   404 ANNKQRVASVVGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADAVAPEWKQLDQFVVNEL 468
            |::|..:..::.|||||||||||||..||:|:|||||||.:||:::.:...||.:..|.|:....
Zfish   353 ASDKLGITMIIAHELAHQWFGNLVTMQWWNDLWLNEGFAKFMEFVSVNITNPELQVEDYFLGKCF 417

  Fly   469 QAVFQLDALSTSHKISHEVFNPQEISEIFDRISYAKGSTIIRMMAHFLTNPIFRRGLSKYLQEMA 533
            :|: ::|:||:||.:|..|.||.:|.|:||.:||.||:.|:.|:..|||..||:.|:.|||:..:
Zfish   418 EAM-EVDSLSSSHPVSTPVENPAQIQEMFDDVSYDKGACILNMLREFLTPKIFKLGIVKYLKHYS 481

  Fly   534 YNSATQDDLWHFLTVEAKSSGL------------------------LDDSRSVKEIMDTWTLQTG 574
            |.:....:||..||....|.||                        .:|...||.:|:|||||.|
Zfish   482 YQNTVNSNLWESLTNVCDSDGLDEGRLKGDESCRHSASNTGASKWHSEDELDVKAMMETWTLQEG 546

  Fly   575 YPVVKVSRHPNSDVIRLEQVRFVYTNTTREDESLLWYIPITF-TTDSELNFANTRPTTWMPRTK- 637
            :|::.::  .....:||.|.|::.::...:..|.||.:|:|: |:||      |....::.:||
Zfish   547 FPLITIA--VKGREVRLSQERYLKSDDLSQTSSFLWQVPLTYITSDS------TTVHRFLLKTKT 603

  Fly   638 --LYELENRELSLAKWFIFNVQQTGYYRVNYDLENW---MAITEHLMDVDNFEDIAPANRAQLID 697
              ||..|.     ..|..|||..:|||.|:|:...|   :.:.:|     |...::..:||.||:
Zfish   604 DVLYLPEE-----VDWIKFNVDMSGYYIVHYEGSGWDDLITLLKH-----NHTALSSNDRASLIN 658

  Fly   698 DVMNLARGSYLSYETAMNLTRYLGHELGHVPWKAAISNFIFIDSMFVNSGDYDL---LKNYLLKQ 759
            :...|.....|..:.|::||.||..|...:|.....:..:.:..:.......:|   :|.|:|:.
Zfish   659 NAFQLVSVGKLPLDKALDLTLYLSKETEIMPVTQGFNELVPLYKLMEKRDMVELENQMKGYILQL 723

  Fly   760 LKKVYDQVGFKDSQDESEDILVKLKRADILSMACHLGHQECIAEASRHFQNWMQTPNPDSNNPIV 824
            .:|:.:|..:.|....||.:|    |:.:|...|..||..|::.|::.|..|..:   |.|..:.
Zfish   724 FQKLIEQQLWTDEGSVSERML----RSYLLLFGCVRGHPPCVSNATQLFNLWRDS---DGNMSLP 781

  Fly   825 PNLRGVVYCSAIQYGTEYEWDFAFERFLKTNVPGEKDLLLNALGCS----KEPWLLYRFLRRGIS 885
            .::...|:  ::...||..|||.||::.::.....|..:..||..|    |..|:    :.:.:.
Zfish   782 NDVTMAVF--SVGARTEDGWDFLFEKYKESMYVSMKSRIKQALMTSPLDHKLKWM----MEQSLE 840

  Fly   886 GQHIRKQDLFRVFAAVSTTVVGQNIAFDFLRNNWQEI--KTYMGSQMSSIHTLFKFATKGFNSKF 948
            |:.|:.|||..|..:||........|:|||:.||..:  |..:||.  ||..:....|..::::.
Zfish   841 GELIKTQDLPYVVTSVSRNPKAYKHAWDFLQANWDSLIKKFDLGSH--SIAHMVVGVTNQYSTRE 903

  Fly   949 QLGEFENFVKDAHWDYD---RPVQQIVEHIETSVDWMNKNYKSIVRWL 993
            .|.|..||......:..   |.:||.||:||.::.||:||...:..||
Zfish   904 MLAEVRNFFSLLQPETGAELRCIQQAVENIEENIRWMDKNLPLLKAWL 951

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	194/506 (38%)
		ERAP1_C	651..976	CDD:463368	89/339 (26%)
erap1b	NP_956500.2	M1_APN-Q_like	54..543	CDD:341064	194/506 (38%)
		ERAP1_C	614..934	CDD:463368	89/339 (26%)