Protein Alignment CG14516 and T12E12.6

DIOPT Version :9

• Sequence 1: NP_651674.3
• Gene: CG14516 / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_500831.2
• Gene: T12E12.6 / 188454
• WormBaseID: WBGene00020465
• Length: 641
• Species: Caenorhabditis elegans
• Alignment Length: 608
• Identity: 162/608 - (26%)
• Similarity: 264/608 - (43%)
• Gaps: 105/608 - (17%)

  Fly   115 PHSIRPLKYNITIEPQLSGNFTFAGSVQIRIRVLEDCYNITMHAEELNISRSDASVHRVQNNGEP 179
            ||:|.||.|::..:..:.....|.||:.:...:.....|||:.|.:|:..| :.|:.|..:..||
 Worm    19 PHNIIPLSYDLLFKLPIHEFNGFTGSMVLHFNLSSLSDNITLDAVDLHSFR-NISLIRSADLTEP 82

  Fly   180 EGDGLRIHKQYLVGAKQFFVIEL-YDKLLKDVEYVVHLRFDGIIEDYLQGFYRSSYEVHNETR-- 241
            ....::|.|:         .:|| ::|.|...:|::      .|.:| .|...:|.|...|.|
 Worm    83 TLKSIKILKE---------KVELKFEKSLFPGQYLL------TIGEY-NGRIGNSSEALFERRNP 131

  Fly   242 WVASTQFQATDARRAFPCFDEPALKANFTLHIARPRNMTTISNMPIVSSNDHATMPSYVWDHFAE 306
            .:.:|..|...|||.|||.|.||:||.|.|.|..|.:  |::....::.:.|.....:....|..
 Worm   132 LLYTTHLQPNHARRLFPCIDHPAVKALFRLSIVHPTD--TVAQSNTIAMDVHVENRKWQRTIFQA 194

  Fly   307 SLPMSTYLVAYAISDFTHIS---SGNFAVWARAD------AIKSAEYALSVGPRILTFLQDFFNV 362
            :..:..||||:::...:::.   ..:|.|..|.:      .::..:.||:    ....|....:|
 Worm   195 TPLLPAYLVAFSVMPDSNLQLSRQTSFGVTVRVNGESRGLVLRVLDCALA----SFEILAGLIDV 255

  Fly   363 TFPLPKIDMIALPEFQAGAMENWGLITFRETAMLYDPGVATANNKQRVASVVGHELAHQWFGNLV 427
            ..||.|||.|.:||:. |.|||||.||..||       :||:.:...:..::.||:||.|.||..
 Worm   256 PLPLNKIDFILVPEYD-GGMENWGHITVSET-------LATSGDDAHLIYLIAHEIAHHWIGNRA 312

  Fly   428 TPSWWSDIWLNEGFASYM-----EYLTADAVAPEWKQLDQFVVNELQAVFQLDALSTSHKISHEV 487
            |...|:.|.|.|....:|     :.|..|.:..:..||.|:|  |:|.|  .|.||..|.:
 Worm   313 TIDSWNWICLQEDLTDWMALKAVKALLTDEIRLQRFQLAQYV--EIQLV--EDFLSPGHSL---- 369

  Fly   488 FNPQEIS-EIFDRISYAKGSTIIRMMAHFLTNPIFRRGLSKYL--QEMAYNSATQDDLWHFLTVE 549
            :.|.:|: |:.:|..|.||..::..: ..:....|...:.|.|  ....||..|....:..:.|
 Worm   370 YMPSKINQELINRHCYLKGVVLLDTL-ESVVGEQFMYSVIKSLVGSHSTYNLTTFTSYFDQIRV- 432

  Fly   550 AKSSGLLDDSRSVKEIMDTWTLQTGYPVVKVSRH-PNSDVIRLEQVRFVYTNTTREDESLLWYIP 613
                   |.:.:|.:|.:.|....|||.:.|..: |:|   ||:|:           ...||.:.
 Worm   433 -------DRNATVGQIYEYWYTTGGYPSILVENNGPSS---RLQQL-----------SRPLWPLK 476

  Fly   614 ITFTTDSELNFANTRPTTWMPRTKLYELENRELSLAKWFIFNVQQTGYYRVNYDLENWMAITEHL 678
            :|.|.        ..|......:.::..||..|      :.|:..|.:.|||||...|.||.:::
 Worm   477 MTSTL--------AIPQFVFSESIVFASENAPL------LVNLNFTSFMRVNYDSLTWTAIFKYM 527

  Fly   679 MDVDNFED---IAPANRAQLIDD 698
                 ||:   .:...||||:.|
 Worm   528 -----FEEPELFSAVGRAQLVSD 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14516	NP_651674.3	Peptidase_M1	113..505	CDD:279741	115/407 (28%)
		M1_APN_2	121..576	CDD:189008	125/474 (26%)
		ERAP1_C	652..974	CDD:288671	17/50 (34%)
T12E12.6	NP_500831.2	GluZincin	25..402	CDD:387391	113/416 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920