Protein Alignment superdeath and AC3.5

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_001256214.1
• Gene: AC3.5 / 179447
• WormBaseID: WBGene00007071
• Length: 1090
• Species: Caenorhabditis elegans
• Alignment Length: 1092
• Identity: 232/1092 - (21%)
• Similarity: 445/1092 - (40%)
• Gaps: 162/1092 - (14%)

  Fly    15 IPLHENL---NMESRPMNAATPTTTTTFS------KGGRRYSVSLTTAILLASFFICTLLAVGFI 70
            |||.|..   .::::|.. |.|.......      |..:|.:.|..:||.|      .||||..|
 Worm    34 IPLSEKAAKEPLQTQPQE-APPAPKPKVQKQKPPVKPKKRIACSPGSAICL------FLLAVAAI 91

  Fly    71 VY-----NFATCAELE----PDSDEDVVCTSYHLRRLKAGHDDTPKYDRD------------VRL 114
            ::     ::.|....|    ..::|.:.......|..|...|...:.|.|            :.|
 Worm    92 IFAAFLGHYLTKQNYEMMQFKSANESMTTCKNFTRSHKKHQDIVNEEDADENASIKQPTKEELAL 156

  Fly   115 PHSIRPLKYNITIEPQLSGNFTFAGSVQIRIRVLEDCYNITMHAEELNISRSDASVHRVQNNGE- 178
            |.:::|:.|::::.|::.||.|. |...:::.:.|....|.::|:::..:|   ::.::|.:.|
 Worm   157 PKNVQPVWYDVSLSPKVGGNGTM-GLAHVKLNIEEPTNKIVLNAKDIEFTR---NLEKIQLSKEV 217

  Fly   179 ------------------PEGDG----------------LRIHKQYLVGAK----------QFFV 199
                              |||.|                ..:......|.|          :...
 Worm   218 TKRAKKSVDSGTNSTSEMPEGSGEEAMATTATTTTTESTTPVSSFVDTGIKVTNIEFDENLEKVT 282

  Fly   200 IELYDKLLKDVEYVVHLRF------DGIIEDYLQGFYRSSYEVHNETRWVASTQFQATDARRAFP 258
            :.|..:|.|....|:.:.|      :..:::|.   |::|   ..:.:.:.:||...:..|..||
 Worm   283 LTLDQELKKGSTVVLKIPFTSKVSNNNGLKEYK---YKNS---EGKEQSMFTTQPSYSYLRHVFP 341

  Fly   259 CFDEPALKANFTLHIARPRNMTTISNMPIVSSNDHATMPSYVWDHFAESLPMSTYLVAYAISDFT 323
            .||:.|.||...:.:...:....::|..:.:.:|.....|.:     ..:....:::...::...
 Worm   342 SFDQEAFKAPAAITLMHSKGSIVVANTGVKTKDDGDAQTSTL-----NKVLDPDFVIGDLVASEV 401

  Fly   324 HISSG-NFAVWARADAIKSAEYALSVGPRILTFLQDFFNVTFPLPKIDMIALPEFQAGAMENWGL 387
            :.:|| ...:|.|.:...|.|.:|....:.:..::...........:|::|:|.||.|...:...
 Worm   402 NTTSGITIRIWTRPEVKHSTEQSLDYANQAIDAMEHILQSRLESKSLDIVAVPGFQTGNRVSPSF 466

  Fly   388 ITFRETAMLYDPGVATANNKQRVASVVGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADA 452
            |...|..:||:......|.|.|:|.::.:.:|.||||.:..|..:...||||....::|....:.
 Worm   467 IVLPEEDILYNEQSNDINQKTRIARMISNRIAAQWFGGITNPEEFGTFWLNEALPRFLEVEALEK 531

  Fly   453 VAPEWKQLDQFVVNELQAVFQLDALSTSHKIS-HEVFNPQEISEIFDRISYAKGSTIIRMMAHFL 516
            :..  ...|.....|::.:.:.||.:||..:. ..||:..:|:||.......||:.::||:...:
 Worm   532 ILD--INSDDLWTYEMEKILERDATATSQPLRVKNVFSSADIAEIDHEFIGKKGAAVLRMIQKSV 594

  Fly   517 TNPIFRRGLSKYLQEMAYNSA--TQDDLWHFL--TVEAKSSGLLDDSRSVKEIMDTWTLQTGYPV 577
            ...:|.:.:..::.  :|.||  ..|.||...  .:..|..|..::...|.:.::||..|.|:|:
 Worm   595 GVNVFNKAIRSFVS--SYRSAYPYDDGLWKSFEKALGGKLKGWNNEPLDVAKFVNTWVDQIGFPL 657

  Fly   578 VKVSRHPNSDVIRLEQVRFVYTNTTREDESLL-------WYIPITFTTDSELNFANTRPTTWMPR 635
            |.|.: .:.:.:.|.|.||...:.|:|.....       |.:|:...:...:.     ..:|
 Worm   658 VSVEK-LDDETVELSQERFKNDHKTKEQFKFRNAKYWFNWEVPLFLKSSGPVG-----NVSW--- 713

  Fly   636 TKLYELENRELSLAKWFIFNVQQTGYYRVNYDLENWMAITEHLMDVDNFEDIAPANRAQLIDDVM 700
              |:|.....|:.:.....|....|.|||||:.:.|..|.:.|  ..:...::...||:||.||.
 Worm   714 --LHEAFRLPLNTSDSIYLNTDSNGVYRVNYEEKRWNDIAKQL--EKSHGKLSERTRARLISDVF 774

  Fly   701 NLARGSYLSYETAMNLTRYLGHELGHVPWKAAISNFIFIDSMFVNSGDYDLLKNYLLKQLKKVYD 765
            .||....|.:|||:|:|.||..|...|||..|...|..:......:...|.|.:::.:::.|.::
 Worm   775 ALANSGALPFETALNVTSYLPMETATVPWLIATRIFKKLTERLEGAPIQDKLNSFIYQKIHKKFE 839

  Fly   766 QVGFKDSQDESEDILVKLKRADILSMACHLGHQECIAEASRHFQNWMQTP-----NPDSNNPIVP 825
            ::.....:..|..:..:| .|::|.:...:..::...:.:..|......|     |..|:...||
 Worm   840 EISSSPGEASSNYLKNRL-YANLLDLMAIVKPEKSNEKLNELFVEGFLAPCQFSGNFSSDCSEVP 903

  Fly   826 -NLRGVVYCSAIQYGTEYEWDFAFE---RFLKTNVPG-EKDLLLNALGCSKEPWLLYRFLRRGIS 885
             :||..|||:.:::|.    |..||   ...:..|.| |||||.|:|.|.::|    |.|||.|.
 Worm   904 GDLREKVYCNGVEFGN----DTVFETVRELAEKEVDGAEKDLLQNSLACFRDP----RALRRLIL 960

  Fly   886 GQHIRKQDLFRVFAAVSTTVVGQNIAFDFLRNNWQEI--KTYMGSQMSSIHTLFKFATKG--FNS 946
            ........:..:...:::..||:.||.:::.:||..:  |.:....    .||...|..|  .::
 Worm   961 DNLNSTSTVTLLLRKMNSRPVGKEIATNWIIDNWSTVLKKKFKNDP----ETLNAIADAGIILDN 1021

  Fly   947 KFQLGEFENFVKDAHWDYD--RPVQQIVEHIETSVDWMNKNYKSIVRWLENE 996
            :.:....|.|::..|....  ..:.:.:|...|.:.|..:....:..:|:.:
 Worm  1022 EREKSMIETFMEHHHKSTHGIESLDKKIEEATTDIYWRKQKINELNDYLDGK 1073

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	98/506 (19%)
		ERAP1_C	651..976	CDD:463368	85/340 (25%)
AC3.5	NP_001256214.1	GluZincin	165..651	CDD:472708	98/504 (19%)
		beta-trefoil_FSCN-like	<685..741	CDD:483951	10/65 (15%)
		ERAP1_C	728..1056	CDD:463368	86/342 (25%)