Protein Alignment CG14516 and Y67D8C.9

DIOPT Version :9

• Sequence 1: NP_651674.3
• Gene: CG14516 / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_001122826.1
• Gene: Y67D8C.9 / 177088
• WormBaseID: WBGene00022073
• Length: 1144
• Species: Caenorhabditis elegans
• Alignment Length: 1189
• Identity: 272/1189 - (22%)
• Similarity: 458/1189 - (38%)
• Gaps: 314/1189 - (26%)

  Fly    24 ESRP--MNAATPTTTTTFSKGGRR----YSVSLTTAILLASFFICTLLAV--------------- 67
            |..|  .|.:....|..|.:..||    ::......|||.:.|:..:||.
 Worm    13 EGEPCIRNGSGAAATVHFRQESRRRKSDFARKCIAVILLHAIFLLAILAALIIGHWISEENQKLS 77

  Fly    68 -----------GFIVYNFATCAELEPDSDEDVVCTSYHLRRLKA--------GHDDTPKYDRDVR 113
                       .:::....|.:...|:|      .|:|...|..        ....||.     |
 Worm    78 NRTMLNITLAEAYLLEGIYTTSTATPES------LSHHHTHLLTTSSAALGQSKKKTPP-----R 131

  Fly   114 LPHSIRPL--KYNITIE----PQLSGNF---------------TFAGSVQIRIRVLEDCYNITMH 157
            :...:.||  |.|.||.    |...|.|               |.|..|.:.:.:|...|::.:.
 Worm   132 VVERLIPLEKKRNFTISDVFPPPADGGFGIAEQLHAVRANKLSTDALLVPLPLYILPYHYDLQLD 196

  Fly   158 AEELN---ISRSDASVHRVQNNGEPEGDGLRIH---------KQYLVGAKQFFV----------- 199
            ..:.:   ..|::.|:| :::.|....|.::.|         .:.....|:|:.
 Worm   197 FSQFDTHLFIRANISIH-LESYGNSTEDEIQFHLGPNIKMERMRLRKDGKKFYAKTFKREESKKL 260

  Fly   200 --IELYDKLLKDVEYVVHLRFDGIIEDYLQGFYRSSYEVHNETRWVA---STQFQATDARRAFPC 259
              |.|.|.|.|. :|::.:.::..|.|......|.|.:....:...|   :|:|:.|.||..|||
 Worm   261 GRISLRDPLQKG-KYILEMTYNMTICDEDVDGVRCSLDNQTNSSLKATSFTTKFEPTLARAFFPC 324

  Fly   260 FDEPALKANFTLHIARPRNMTTISNMPIVSSNDHATMPSYVWDH------FAESLPMSTYLVAYA 318
            :|||.:||.|.:.:...:..|.:||||.|.|:||.:     |:.      |..:.||||||:|:|
 Worm   325 WDEPGVKATFNISVRHNKKYTVLSNMPPVESHDHKS-----WEDQFKTTVFQTTPPMSTYLLAFA 384

  Fly   319 ISDFTHISSGN-----FAVWARADAIKSAEYALSVGPRILTFLQDFFNVTFPLPKIDMIALPEFQ 378
            |.:|..:.|..     ..||...:.:.|.::.|...|.|...|:|...:.:||||:|:||...|.
 Worm   385 IGEFVKLESRTERGIPVTVWTYPEDVMSMKFTLEYAPVIFDRLEDALEIPYPLPKVDLIAARNFH 449

  Fly   379 AGAMENWGLITFRETAMLYDPGVA-----TAN---NKQRVASVVGHELAHQWFGNLVTPSWWSDI 435
            .|.||||||:.|...::.|.|.:.     |.:   |:.|:..::.||.||||||||||...||::
 Worm   450 VGGMENWGLVVFEFASIAYTPPITDHVNETVDRMYNEFRIGKLIAHEAAHQWFGNLVTMRDWSEL 514

  Fly   436 WLNEGFASYMEYLTADAVAPEWKQLDQFVVNELQAVFQLDALSTSHKIS--HEVFNPQEISEIFD 498
            :||||||::..|   :.::.|.....||...:..|...|......|::|  .|:....::...|.
 Worm   515 FLNEGFATFYVY---EMMSTERPVTAQFEYYDSLASLILAQSEEDHRLSLVRELATESQVESSFH 576

  Fly   499 RIS-YAKGSTIIRMMAHFLTNPIFRRGLSKYLQEMAYNSATQDDLWHFLTVEAKSSGLLDDSRSV 562
            ..: |.||..:|||:...:::..|:..:.:||::.||.|.::|||:..|...|....   :...:
 Worm   577 PTNLYTKGCVLIRMLRDLVSDFDFKAAVRRYLRKNAYRSVSRDDLFASLPAYADHGA---EQEKL 638

  Fly   563 KEIMDTWTLQTGYPVVKVSRHPNSDVIRLEQVRFVY----------------------------- 598
            ..:::.|.:..|.|.:.:.|:.:::::.:.|.:.|:
 Worm   639 SHVLEGWFVNEGIPEITLIRNYDNEMMTISQRKTVHHEYRSFLKDRKASASVRYRGSRSAEDGST 703

  Fly   599 ---------------------------TNT-------TREDE----------SLLWYIPITF--- 616
                                       |:|       :|.||          ..||.||||:
 Worm   704 LFDDALFDGYIEKKKDRRRKHRPIRRKTSTPPSISPISRRDELRKPRRVGASQDLWTIPITYMFG 768

  Fly   617 ---TTDSEL--NFANTRPTTWMPRTKLYELENRELSLAKWFIFNVQQTGYYRVNYDLENW--MAI 674
               |::.::  .|       |: :.:.....:.|:|..:..:.|.:....|||||||.||  :|.
 Worm   769 SLKTSEGQVIREF-------WL-KNRTVSFGDAEISPNQAVLVNPEWKYPYRVNYDLLNWKLLAR 825

  Fly   675 TEHLMDVDNFEDIAPANRAQLIDDVMNLARGSYLSYETAMNLTRYLGHELGHVPWKAAISNFIF- 738
            |.|    .|..:|...:|.|||.|.     ..:||.....:|..||   ||::..:..:...:|
 Worm   826 TLH----QNHLEINEKSRMQLILDA-----EYFLSNSVNPHLYLYL---LGYLAHETKMEVMLFG 878

  Fly   739 IDSMFVNSGDYDLLKNYLLKQLKK--------VYDQVG--FKDSQDESEDI---LVKLKR-ADIL 789
            ||::      |..:..|...||.|        |..|:.  ..:||.::|..   ||:.:| |.:.
 Worm   879 IDAV------YKFIDVYKATQLNKAILVYFEPVISQMDHLLNESQVDAETASLWLVRPERLAKLY 937

  Fly   790 SMACHLGHQECIAEASRHFQNWMQTPNPDSNNPIVPNLRGVVYCSAIQYGTEYEWD-------FA 847
            .|.|..|...|  :...:.|.|.::|:                          ||.       .|
 Worm   938 QMRCAAGLSSC--KNDYYTQRWSRSPD--------------------------EWTEDVHKQVTA 974

  Fly   848 FERFLKTNVPGE----KDLLLNALGCSKEPWLLYRFLRRGISGQHIRKQDLFRVFAAVSTTVVGQ 908
            ....|.||.|.|    :|||.:.|..|...|.|...|......|.:.::....:.:..:..|...
 Worm   975 VCHQLFTNTPDEVKTVQDLLDSRLQSSGAKWALTVQLAACSHDQKLLRRTARAIVSTKNAVVYAS 1039

  Fly   909 NIAFDFLRNNWQEIKTYMGSQMSSIHTLFKFATKGFNSKFQLGEFENFVKDAHWDYDRPVQQIVE 973
            .:..||..:.....:.|:.::::.:.|..|.|....||...|                |..:|:.
 Worm  1040 ALQSDFSLHYNPTFRKYLWAEIAKMSTFEKTALFSTNSTDIL----------------PASRILL 1088

  Fly   974 HIETSVDWMNKNYKSIVRW 992
            |...::|.:.:....:..|
 Worm  1089 HSVKTIDELQQIRGLLTNW 1107

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14516	NP_651674.3	Peptidase_M1	113..505	CDD:279741	130/462 (28%)
		M1_APN_2	121..576	CDD:189008	146/525 (28%)
		ERAP1_C	652..974	CDD:288671	80/349 (23%)
Y67D8C.9	NP_001122826.1	Peptidase_M1	182..584	CDD:279741	117/411 (28%)
		M1_APN_2	190..652	CDD:189008	134/474 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020