Protein Alignment CG14516 and mnp-1

DIOPT Version :9

• Sequence 1: NP_651674.3
• Gene: CG14516 / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_497878.1
• Gene: mnp-1 / 175564
• WormBaseID: WBGene00007139
• Length: 781
• Species: Caenorhabditis elegans
• Alignment Length: 831
• Identity: 160/831 - (19%)
• Similarity: 305/831 - (36%)
• Gaps: 224/831 - (26%)

  Fly    29 NAATPTTTTT------------FSKGGRRYSVSLTTAILLASFFICTLLAVGFIVYNFATCAEL- 80
            :|.||:||||            |.:..:....|.:|.....:....|......||......:.|
 Worm    75 SATTPSTTTTRIEETTTTTSGAFDESVKNSEASTSTIPTTEAVPTTTATDAPEIVMPVDVASILK 139

  Fly    81 EPDSDEDVVCTSYHLRRLKAGHDDTPKYDRDVRLPHSIRPLKY--NITI----EPQLSGNFTFAG 139
            :...|.::|.....::.|..  ..||........|...:|:.|  ||||    :|.|.|:.....
 Worm   140 DKTKDFEIVEKCAEIQALPV--SCTPSQSPLTSDPSKFQPIHYVLNITIRDVRKPVLEGHMQLFA 202

  Fly   140 SVQIRIRVLEDCYNITMHAEELNISRSDASVHRVQNNGEPEGDGL---RIHKQYLVGAKQFFVIE 201
            |.:.:::.      |::|:.:::...:...:|.|..|   .|:.:   |:|:           |:
 Worm   203 STKDQVQA------ISLHSVKIHNLENRDRIHVVNCN---TGETICVSRVHQ-----------ID 247

  Fly   202 --LYDKLLKDVEYVVHLRFDGIIEDYLQGFYRSSYEVH-----NETRW----VASTQFQATDARR 255
              ::.:|.:.:...|:||.|      :.||..:....|     ...:|    :..:.|:.|.||.
 Worm   248 DLIHLELAQSISSGVNLRVD------IDGFISADSGPHVFKQIPTAKWRVPQMIGSVFEPTSARH 306

  Fly   256 AFPCFDEPALKANFTLHIARPRNMTTISNM---PIVSSND----HATMP------SYVWDHFAES 307
            .||.||....|:.|.|.:....:|:.|:|.   |.||::.    ..|:|      |:|  .|.::
 Worm   307 VFPSFDLHNQKSTFNLCLNHGPSMSAIANSLINPNVSTSGISCFEKTVPLIAQQLSFV--AFEKT 369

  Fly   308 LPM----STYLVAY--AISDFTHISSGNFAVWARADAIKSAEYALSVGPRILTFLQDFFNVTFPL 366
            .|:    :|...||  .|....::::.||         |..|:..|...:::..:..:...::||
 Worm   370 NPLFYNTTTMDGAYLPEIDMIFNLNAKNF---------KQYEWIHSEVSKVMALMSKWSGFSYPL 425

  Fly   367 PKIDMIALPEFQAG--AMENWGLITFRETAMLYDPGVATANNKQRVASVVGHELAHQWFGNLVTP 429
            .:::::..| .|||  |:   |:||....|:.|..  .|:.::..:..|:|     ||...:||.
 Worm   426 TRLEIVVAP-VQAGHSAL---GVITLPAQAIAYQK--HTSTHETLIKEVIG-----QWMEGVVTT 479

  Fly   430 SWWSDIWLNEGFASYMEYLTADAVAPEWKQLDQFVVNELQAVFQLDALSTSHKISHEVFNPQEIS 494
               ......:...:|:          |||      :||     :|..:..:.|:......|:.::
 Worm   480 ---EHTCFEKALIAYV----------EWK------INE-----ELQIVKKTRKMEVSKIRPRNLN 520

  Fly   495 EIFDRISYAKGSTIIRMMAHFLTNPIFRRGLSKYLQEMAYNSATQDDLWHFLTV----------E 549
            |..|.:...:.   |:..:..|.:|.|        .|:.|   |.|:.:...||          .
 Worm   521 ETADSVRVLRQ---IKSQSSNLCSPRF--------VEVFY---TLDETYGQETVIGMIRVIFDKF 571

  Fly   550 AKSSGLLDDSRSVKEIMDTWTLQTGYPVVKVSRH----PNSDVIRLEQVRFVYTNTTREDESL-- 608
            |.|:..:.|..|..|     |...|.|......|    |:|.:.| ..:|.|.::.:.|...|
 Worm   572 AFSTATISDWASAAE-----TATGGRPEAGALIHQWYRPSSTISR-PVLRAVVSSNSVEFNQLTE 630

  Fly   609 -LWYIPITFTTDSELNFANTRPTTWMPRTKLYELENRELSL----AKWFIFNVQQTGYYRVNYDL 668
             .|.:|:..:..:              .|:|..:..::.::    :.:.:.:..:..:..|.||.
 Worm   631 ETWTVPLEISGSA--------------GTQLAVISEKKQAIPFVSSDYVVVDAGRKSHAFVVYDA 681

  Fly   669 ENWMAITEHLMDV--------DNFEDIAPANRAQLIDDVMN--LARGSYLSYETAMNLTRYLGHE 723
            :.::.:.....|.        ..|.|:..|..|.::....|  :|:
 Worm   682 DTYLRLIRCFGDSRCPSKEIGGIFSDLGAALLANILPKPENQDVAK------------------- 727

  Fly   724 LGHVPWKAAISNFIFIDSMFVNSGDYDLLKNYLLKQLKKVYDQVGFKDSQD 774
                 ||   |.|.|:....:..|.......:.:::::|    ..:.|.||
 Worm   728 -----WK---SVFKFMAQQNIVEGTAACCVEHAIREMRK----CSYWDIQD 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14516	NP_651674.3	Peptidase_M1	113..505	CDD:279741	91/432 (21%)
		M1_APN_2	121..576	CDD:189008	106/505 (21%)
		ERAP1_C	652..974	CDD:288671	20/133 (15%)
mnp-1	NP_497878.1	Peptidase_M1	172..556	CDD:279741	99/469 (21%)
		GluZincin	<294..>480	CDD:301352	51/210 (24%)
		GluZincin	<547..602	CDD:301352	14/62 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910