Protein Alignment CG14516 and Y53F4B.20

DIOPT Version :9

• Sequence 1: NP_651674.3
• Gene: CG14516 / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: NP_497105.3
• Gene: Y53F4B.20 / 175160
• WormBaseID: WBGene00013166
• Length: 694
• Species: Caenorhabditis elegans
• Alignment Length: 651
• Identity: 142/651 - (21%)
• Similarity: 240/651 - (36%)
• Gaps: 140/651 - (21%)

  Fly   106 PKYDRDVRLPHSIRPLKYNITIE-----------PQLSGNFT---------------FAGSVQIR 144
            |.|..| |||..::||.|::.::           |..:|...               .:.|...|
 Worm    25 PLYSDD-RLPPILKPLSYDLQLQLPLSEVSDPDVPLFTGRCVMHFEINQQIGPESAFISDSTSNR 88

  Fly   145 IRVLEDC--------YNITMHAEEL---NISRSDASVHRVQNNGEPEGDGLRIHKQYLVGAKQFF 198
            .|:..|.        .::.|:..||   |:..:|.|:.            |.:.:..|...:...
 Worm    89 ARIKFDIIMLDHFENVSLVMNGHELEIFNVQLTDDSME------------LSVDQPVLFPGRYTL 141

  Fly   199 VIELYDKLLKDVEYVVHLRFDGIIEDYLQGFYRSSYEVHNETRWVASTQFQATDARRAFPCFDEP 263
            .|.               |:.|:|...:  :||.:.|     ..|..:......|...||.:...
 Worm   142 TIH---------------RYKGLIGSAI--YYRDAGE-----HAVFGSNLFPNRAPAVFPSYLAS 184

  Fly   264 ALKANFTLHIARPRNMTTISNMPIVS-SNDHATMPSYVWDHFAESLPMSTYLVAYAIS------- 320
            ..|..|::.:..|     :..:.:.| ||:.|  |..:    .|:..|:|:....:|:
 Worm   185 TEKVTFSITMVHP-----VGTLALTSGSNEGA--PRKI----DENWQMTTFSTTPSITPSMLCFL 238

  Fly   321 ----DFTHISSG----NFAVWARADAI--KSAEYALSVGPRILTFLQDFFNVTFPLPKIDMIALP 375
                ::|||.|.    |.:|......:  :..::.|....::|..|:|.|:...|:||||:|.:.
 Worm   239 LLPHEYTHIESTYTGVNISVHYNRFRVQKEQTKHLLHTATQVLALLKDIFSSLIPVPKIDIITMN 303

  Fly   376 EFQAGAMENWGLITFRETAMLYDPGVATANNKQRVASVVGHELAHQWFGNLVTPSWWSDIWLNEG 440
            |..:.|.  :|.|...|....   ....||..:.:|:    .||.||.|.....|..|::.|.|.
 Worm   304 EVSSTAC--FGSIVVSEVQFF---SADYANQVKMLAT----WLAKQWIGGYAAISEGSELCLQED 359

  Fly   441 FASYMEYLTADAVAPEWKQLDQFV-VNELQAVFQLDALSTSHKISHEVFNPQEISEIFDRISYAK 504
            ..:::    ||.|...... |:|. :..|..::..:.:.|:........:|.|. |||::.. .|
 Worm   360 LVAFI----ADKVIKRMTN-DEFTRLGHLAKIYLSETIFTAGDTLKLDEHPNEF-EIFEKCG-LK 417

  Fly   505 GSTIIRMMAHFLTNPIFRRGLSKYLQEMAYNSATQDDLWHFLTVEAKSSGLLDDSRSVKEIMDTW 569
            |..    |...:.:.|..:.:...:.||.|||  :...:...|:....:..:|:...|.:::..|
 Worm   418 GVA----MLESIESLIGEKSMISKINEMIYNS--KKGSYSSRTLYGLLNSTVDEDIYVSQLLHYW 476

  Fly   570 TLQTGYPVVKVSRHPNSDVIRLEQVRFVYTNTTREDESL-LWYIPITFTTDSELNFANTRPTTWM 633
            ....|.|.:.|.|..||..|..........|.....|.: ||.:|:.||   |...    |...|
 Worm   477 HEHGGLPYMNVDRLANSIKITQNGSNMTVKNGAGTWERMPLWPLPLKFT---EFKL----PIQIM 534

  Fly   634 PRTKLYELENRELSLAKWFIF-NVQQTGYYRVNYDLENWMAITEHLMDVDNFEDIAPANRAQLID 697
            ....::....|:     ..|| |:..|.|||||||::.|..|...|  .:|........|.||:.
 Worm   535 VSHGIHLSPIRD-----GLIFSNLGFTNYYRVNYDIDTWREIKTVL--TENATSYTLRERFQLVS 592

  Fly   698 D 698
            |
 Worm   593 D 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14516	NP_651674.3	Peptidase_M1	113..505	CDD:279741	89/447 (20%)
		M1_APN_2	121..576	CDD:189008	99/510 (19%)
		ERAP1_C	652..974	CDD:288671	19/48 (40%)
Y53F4B.20	NP_497105.3	GluZincin	39..>300	CDD:301352	55/305 (18%)
		ERAP1_C	552..>593	CDD:288671	16/42 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167075
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840