Protein Alignment superdeath and LOC1275101

DIOPT Version :10

• Sequence 1: NP_651674.3
• Gene: superdeath / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: XP_314331.5
• Gene: LOC1275101 / 1275101
• VectorBaseID: AGAMI1_000111
• Length: 915
• Species: Anopheles gambiae
• Alignment Length: 933
• Identity: 257/933 - (27%)
• Similarity: 427/933 - (45%)
• Gaps: 123/933 - (13%)

  Fly   113 RLPHSIRPLKYNITIEPQLSGN-FTFAGSVQIRIRVLEDCYNITMHAEELNISRSDASVHRVQNN 176
            |||::..|..|.:.::..:... |.:.|:|||||.|||....|.:|:     |||:.:..:::|
Mosquito    40 RLPNTTVPTHYTLRLDTDIHREIFDYTGNVQIRINVLEATDQIVLHS-----SRSEITHVQLRN- 98

  Fly   177 GEPEGDGLRIH-KQYLVGA-KQFFVIELYDKLLKDV-EYVVHLRF-DGIIEDYLQGFYRSSYEVH 237
                |.||.:. |.:.... |:|.|:.:...|..:. .|.:.:.| :.|..:...|||||||:..
Mosquito    99 ----GVGLSVPVKNFEFDEDKEFLVVNVGTTLQPNTGTYTLEIDFTNSIARNDQAGFYRSSYDDE 159

  Fly   238 NET-RWVASTQFQATDARRAFPCFDEPALKANFTLHIARPRNMTTISNMPI-----------VSS 290
            |.. |::..|||::.|||.:|||:|||.:|..:.:.|....:....||.|:           :|:
Mosquito   160 NGVRRYLGLTQFESVDARTSFPCYDEPGIKTTYDILIVCGIDYHARSNAPLRGIQLLEGGKKLST 224

  Fly   291 NDHATMPSYVWDHFAESLPMSTYLVAYAISDFTH----ISSGNFAV--WARADAIKSAEYALSVG 349
                         ||.:..|.|||||:.:|||.:    ::....|:  |::..::....|::...
Mosquito   225 -------------FATTPRMQTYLVAWLVSDFKYEREVLTDPQLAIASWSKPSSVHLLSYSVDAS 276

  Fly   350 PRILTFLQDFFNVTFPLPKIDMIAL--PEFQAGAMENWGLITFRETAMLYDPGVATANNKQR--- 409
            .|.:..::::|:..:.:.|||.:|:  .::.|||||||||:|::|:|:.|.|    .:.:||
Mosquito   277 KRFMRAMEEYFDQLYSMSKIDNVAIKDEDYAAGAMENWGLVTYKESAISYGP----EDGEQRQVG 337

  Fly   410 VASVVGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADAVAPEWKQLDQFVVNELQAVFQL 474
            |.::||||..||:||||:.|.|||.:|||||||...:|.......||.:..::||....|...:.
Mosquito   338 VVTIVGHEFTHQFFGNLLAPKWWSYLWLNEGFARLYQYYLGAISHPELQLRERFVTGPFQTALRA 402

  Fly   475 DALSTSHKISHEVFNPQEISEIFDRISYAKGSTIIRMMAHFLTNPIFRRGLSKYLQEMAYNSATQ 539
            |...|...:::.......||.:||.|:|.|.:.::|||.:.|....|::||..|||:.......:
Mosquito   403 DNSLTVRPMTYYTETRPSISRLFDSIAYDKSACVLRMMNYALGERTFQKGLRYYLQQNKERGVVE 467

  Fly   540 D-DLWHFLTVEAKSSGLLDDSRSVKEIMDTWTLQTGYPVVKVSRHPNSDVIRLEQVRFVYTNTTR 603
            : :|:..|...||...:|..|.|:.||..:|:.|.|.|:|||.|..|..:  ..|.|::......
Mosquito   468 ESNLFDSLEQAAKEDAVLPISLSIHEIFGSWSHQPGVPLVKVRRDGNEYL--FTQERYIANTPPE 530

  Fly   604 EDESLLWYIPITFTTDSELNFANTRPTTWMP---RTKLYELENRELSLAKWFIFNVQQTGYYRVN 665
            |.....|:|||:|:|.|. |.....|..|||   ....|.:|..:..:..   ||...||||||.
Mosquito   531 EPFENSWWIPISFSTPSN-NAFEKLPAFWMPPNVSEVAYTIETVQDEVVS---FNPHSTGYYRVE 591

  Fly   666 YDLENWMAITEHL-MDVDNFEDIAPANRAQLIDDVMNLARGSYLSYETAMNLTRYLGHELGHVPW 729
            |:......:.|.: .|...||   ||.||:||||.:|:|:....:|:..:.|..||..|..:|||
Mosquito   592 YEESMLRELIERINKDHTGFE---PATRARLIDDTLNIAQSRGGNYDVVLQLLNYLQRETDYVPW 653

  Fly   730 KAAISNFIFIDSMF-VNSGDYDLLKNYLLKQLKKVYDQVGFKDSQDESEDILVKLKRADILSMAC 793
            ..|..|...:.||. .|.....||:.::.|....:.::.|......||..  |...|...:.:||
Mosquito   654 AVAYENLRHMQSMLRTNEAVSQLLERFIEKIASPLLERYGVDHRTGESAS--VGELRTIAIDLAC 716

  Fly   794 HLGHQECIAEASRHFQNWMQTPNPDSNNPIVPNLRGVVYCSAIQYGTEYEWDFAFERFLKT---- 854
            . |.|.|..:|    |:.:::.....:..:..|   .:.|..:|.....:......:|.:.
Mosquito   717 S-GSQSCKDDA----QSAVRSLASKKHYTMEDN---ALLCHGLQQSNAEQRKSLQAQFSQVLSDK 773

  Fly   855 --NVPGEKDLLLNALGCSKEPWLLYRFLRRGISGQHIRKQDLFRVFAAVSTT---------VVGQ 908
              :.|..|..||.:|.|              :.|...:.|...:...|:|.:         :|..
Mosquito   774 NLDNPSAKQFLLQSLSC--------------LGGDMTKVQSFAKYLLALSESDRTKALHRLLVEL 824

  Fly   909 NIAFDFLRNNWQEIKTYMGSQMSSIHTLFKFATKGFNSKFQLGEFENFVKDAHW------DYDRP 967
            |:..       .||...:.|::|...:...:...|....|::..:.....|...      .||..
Mosquito   825 NVPL-------AEIVQSLQSELSQRRSNSVYYKHGPKLIFEIARYVTDPADVQLLSSVASSYDSW 882

  Fly   968 V-QQIVEHIETSVDWMNKNYKSI 989
            | .:|.:.:..:::|:.:|.:.:
Mosquito   883 VASEIEQQVNANLNWVEQNVEPL 905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
superdeath	NP_651674.3	M1_APN-Q_like	121..571	CDD:341064	148/478 (31%)
		ERAP1_C	651..976	CDD:463368	78/348 (22%)
LOC1275101	XP_314331.5	None