Protein Alignment CG14516 and anpep

DIOPT Version :9

• Sequence 1: NP_651674.3
• Gene: CG14516 / 43444
• FlyBaseID: FBgn0039640
• Length: 999
• Species: Drosophila melanogaster
• Sequence 2: XP_031755081.1
• Gene: anpep / 100492262
• XenbaseID: XB-GENE-981369
• Length: 977
• Species: Xenopus tropicalis
• Alignment Length: 1011
• Identity: 345/1011 - (34%)
• Similarity: 534/1011 - (52%)
• Gaps: 123/1011 - (12%)

  Fly    29 NAATPTTTTTFSKGGRRYSVSLTTAILLASFFICTLLAVGFIVYNFATCAELEPDSDEDVVCTSY 93
            :.|.|..||| |..|...:.:.|||...|:                ||.|:
 Frog    42 DVAKPPETTT-SSSGTSTATTTTTATATAT----------------ATTAQ-------------- 75

  Fly    94 HLRRLKAGHDDTPKYDRDVRLPHSIRPLKYNITIEPQL----SGNFTFAGSVQIRIRVLEDCYN- 153
                   .:|...||    |||.::.|:.|::.::|.|    .|.:.|.|. .....:..|..:
 Frog    76 -------SNDPWNKY----RLPKTLSPVHYDVELQPFLVKNADGLYVFRGK-STAFFICNDATDL 128

  Fly   154 ITMHAEELNISRSDASVHRVQNNGEPEGDG---LRIHKQYLVGAKQFFVIELYDKLLKDVEYVVH 215
            |.:|:.:||.::.::...::|       ||   :.:...:....|||.|::....|:...:|.::
 Frog   129 IIIHSNKLNHTKFNSFDAKLQ-------DGATDVALKSTFFQKDKQFLVVQAAANLVPGKQYGLY 186

  Fly   216 LRFDGIIEDYLQGFYRSSYEVHNETRWVASTQFQATDARRAFPCFDEPALKANFTLHIARPRNMT 280
            ..|.|.:.|.|.|||||.|.....|:.:|:||.||.|||:|||||||||:||.|.:.:...:...
 Frog   187 TEFVGELADDLAGFYRSEYLEDGVTKIIATTQMQAPDARKAFPCFDEPAMKATFNITLKYRQPYK 251

  Fly   281 TISNMPIVSSNDHATM----PSYVWDHFAESLPMSTYLVAYAISDFTHISS-GNFAV-----WAR 335
            .:|||..:   |.:|:    ..:....|.::..||:||||:.:|:|..:.. ||..|     |.|
 Frog   252 AMSNMREI---DRSTVTEDGQQWTVSKFDKTPKMSSYLVAFIVSEFEAVGDPGNATVTGVQIWGR 313

  Fly   336 ADAIK---SAEYALSVGPRILTFLQDFFNVTFPLPKIDMIALPEFQAGAMENWGLITFRETAMLY 397
            ..||:   ..||||||...||.|..:::...:||||.|.:|||:|.|||||||||:|:||||:|:
 Frog   314 KKAIQDENQGEYALSVTKPILDFFAEYYRTPYPLPKSDQVALPDFSAGAMENWGLVTYRETALLF 378

  Fly   398 DPGVATANNKQRVASVVGHELAHQWFGNLVTPSWWSDIWLNEGFASYMEYLTADAVAPEWKQLDQ 462
            |..|::..||:||.:|:.|||||||||||||..||:|:|||||||||:|||.||...|.|...|.
 Frog   379 DDQVSSIGNKERVVTVIAHELAHQWFGNLVTIRWWNDLWLNEGFASYVEYLGADKAEPNWNIKDL 443

  Fly   463 FVVNELQAVFQLDALSTSHKIS---HEVFNPQEISEIFDRISYAKGSTIIRMMAHFLTNPIFRRG 524
            .|:|::..|..:|||::||.::   .||.:|.|||.:||.|:|:||:::|||::.|||.|:|..|
 Frog   444 IVLNDVHRVMAVDALASSHPLTSREDEVNSPSEISALFDSIAYSKGASVIRMLSEFLTEPLFVDG 508

  Fly   525 LSKYLQEMAYNSATQDDLWHFLTVEAKSSGLLDDSRSVKEIMDTWTLQTGYPVVKV--------S 581
            |:.||:...|::....|||..|.....:...:.....:|:|||||.||.|:||||:        .
 Frog   509 LASYLKGFEYSNTVYSDLWTHLQWAVNNQTAVKLPLPIKDIMDTWVLQMGFPVVKIDTATGVVTQ 573

  Fly   582 RH----PNSDVIRLEQVRFVYTNTTREDESLLWYIPITFTTDSELNFANTRPTTWMPRTKLYELE 642
            :|    |:|.|.|...  |.|.          |.:||::...|:      ....|: :.:...:|
 Frog   574 KHFLLDPDSVVTRPSP--FDYK----------WKVPISYKISSK------EDNIWL-QNESETVE 619

  Fly   643 NRELSLAKWFIFNVQQTGYYRVNYDLENWMAITEHLMDVDNFEDIAPANRAQLIDDVMNLARGSY 707
            :.:::...|.:.|:..|||||||||..||..:...|.  .:.:.|...||||:|||..||||...
 Frog   620 DFKITGNDWLLVNLNVTGYYRVNYDDNNWSRLLNQLQ--TSHQAIPVINRAQIIDDAFNLARAKQ 682

  Fly   708 LSYETAMNLTRYLGHELGHVPWKAAISNFIFIDSMFVNSGDYDLLKNYLLKQLKKVYDQVGFKDS 772
            ::...|::.|:|:..:..::||:||:|...:...||..:..:..:|.|:..|:..:::.  ||..
 Frog   683 ITTIQALDTTKYISADREYMPWQAALSGLSYFTQMFDRTEVFGPMKKYMKMQVNPLFEY--FKQE 745

  Fly   773 QDESEDILVKLK----RADILSMACHLGHQECIAEASRHFQNWMQTPNPDSNNPIVPNLRGVVYC 833
            .....:..|.|.    ..:.||.||....::|:..||..|..||.||   ..|.|.||||..|||
 Frog   746 TGNWTNRPVSLTDQYCEINTLSTACSYDIEDCLKFASELFSQWMATP---QQNNIHPNLRTNVYC 807

  Fly   834 SAIQYGTEYEWDFAFERFLKTNVPGEKDLLLNALGCSKEPWLLYRFLRRGISGQHIRKQDLFRVF 898
            :|:..|.|.||:|.::||..|::..|:|.|..||.||||||:|.|||...:....||:||.....
 Frog   808 TAVAQGGEQEWNFVWDRFQLTDIAQEQDKLRAALACSKEPWILNRFLEYSLDPTMIRRQDAVSTI 872

  Fly   899 AAVSTTVVGQNIAFDFLRNNWQEIKTYMGSQMSSIHTLFKFATKGFNSKFQLGEFENFVKD---- 959
            ::|....:||::|:||:|..|:.:.:..|....|...|.:..|:.|:::|:|.:...|..|
 Frog   873 SSVVNNPIGQSLAWDFVRAKWKTLYSMFGESSFSFGNLIERVTRRFSTEFELQQLLQFKADNQNP 937

  Fly   960 AHWDYDRPVQQIVEHIETSVDWMNKNYKSIVRWLEN 995
            ......:.::|.:|..:.:::|:|:|..::.:|.|:
 Frog   938 GFGTASQALEQAIEKTKANINWVNQNKAAVKKWFED 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14516	NP_651674.3	Peptidase_M1	113..505	CDD:279741	167/415 (40%)
		M1_APN_2	121..576	CDD:189008	191/478 (40%)
		ERAP1_C	652..974	CDD:288671	109/329 (33%)
anpep	XP_031755081.1	M1_APN-Q_like	92..555	CDD:341064	188/473 (40%)
		ERAP1_C	628..955	CDD:403137	111/333 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	249	1.000	Domainoid score	I2083
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68163
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X67
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.110