Protein Alignment Vha100-1 and Vha100-2

DIOPT Version :10

• Sequence 1: NP_651672.1
• Gene: Vha100-1 / 43442
• FlyBaseID: FBgn0028671
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_650722.1
• Gene: Vha100-2 / 42216
• FlyBaseID: FBgn0028670
• Length: 834
• Species: Drosophila melanogaster
• Alignment Length: 861
• Identity: 503/861 - (58%)
• Similarity: 615/861 - (71%)
• Gaps: 46/861 - (5%)

  Fly     1 MGSLFRSEEMALCQLFLQSEAAYACVSELGELGLVQFRDLNPDVNAFQRKFVNEVRRCDEMERKL 65
            ||.:||||||||||:|:|.||||..||||||.|.|||||||.:|||||||||.|||||||:|||:
  Fly     1 MGDMFRSEEMALCQMFIQPEAAYTSVSELGETGCVQFRDLNVNVNAFQRKFVTEVRRCDELERKI 65

  Fly    66 RYLEKEIKKDGIPMLDTGES-PEAPQPREMIDLEATFEKLENELREVNQNAEALKRNFLELTELK 129
            ||:|.|||||||.:.|..:. |.||.|||:|||||..||.|:|:.|:.||...:|.|:||||||:
  Fly    66 RYIETEIKKDGIVLPDIQDDIPRAPNPREIIDLEAHLEKTESEMIELAQNEVNMKSNYLELTELR 130

  Fly   130 HILRKTQVFF-DESVPTVYKSSGAYSSSKYRRYPQMADNQNEDEQAQLLGEEGVRASQPGQNLKL 193
            .:|..||.|| |:.|..:..|:.|           ..||   |..||..|             :|
  Fly   131 KVLENTQGFFSDQEVLNLDSSNRA-----------GGDN---DAAAQHRG-------------RL 168

  Fly   194 GFVAGVILRERLPAFERMLWRACRGNVFLRQAMIETPLEDPTNGDQVHKSVFIIFFQGDQLKTRV 258
            |||||||.|||:.||||||||..||||||:::.::.||.||..|..::|:||:.||||:|||.|:
  Fly   169 GFVAGVINRERVFAFERMLWRISRGNVFLKRSDLDEPLNDPATGHPIYKTVFVAFFQGEQLKNRI 233

  Fly   259 KKICEGFRATLYPCPEAPADRREMAMGVMTRIEDLNTVLGQTQDHRHRVLVAAAKNLKNWFVKVR 323
            ||:|.||.|:|||||.:..:|.||...|.||:|||..||.||:|||.|||...:|||.:|.:.|:
  Fly   234 KKVCTGFHASLYPCPSSHNEREEMVRNVRTRLEDLKLVLSQTEDHRSRVLATVSKNLPSWSIMVK 298

  Fly   324 KIKAIYHTLNLFNLDVTQKCLIAECWVPLLDIETIQLALRRGTERSGSSVPPILNRMQTFENPPT 388
            |:|||||||||||:|||:||||.|||||..|:..:|.||..|:...||::|..||.:.|.|.|||
  Fly   299 KMKAIYHTLNLFNMDVTKKCLIGECWVPTNDLPVVQKALSDGSAAVGSTIPSFLNVIDTNEQPPT 363

  Fly   389 YNRTNKFTKAFQALIDAYGVASYREMNPAPYTIITFPFLFAVMFGDLGHGAIMALFGLWMIRKEK 453
            :|||||||:.||.||||||||||||.|||.||.|||||||||||||||||.|:.|||.||:..|:
  Fly   364 FNRTNKFTRGFQNLIDAYGVASYRECNPALYTCITFPFLFAVMFGDLGHGLILVLFGAWMVLCER 428

  Fly   454 GLAAQKTDNEIWNIFFGGRYIIFLMGVFSMYTGLIYNDIFSKSLNIFGSHWHLSYNKSTVMENKF 518
            .||..:...|||||||||||||.|||:|:|||||:|||:||||:|:|||.|..:||.:||:.|..
  Fly   429 KLARIRNGGEIWNIFFGGRYIILLMGLFAMYTGLVYNDVFSKSMNLFGSRWFNNYNTTTVLTNPN 493

  Fly   519 LQLSPKGDYEGAPYPFGMDPIWQVAGANKIIFHNAYKMKISIIFGVIHMIFGVVMSWHNHTYFRN 583
            |||.|.....|. |||||||:||:|. |||||.|::|||:||||||:||:|||.||..|.|:|:.
  Fly   494 LQLPPNSSAVGV-YPFGMDPVWQLAD-NKIIFLNSFKMKLSIIFGVLHMVFGVCMSVVNFTHFKR 556

  Fly   584 RISLLYEFIPQLVFLLLLFFYMVLLMFIKWIKF-AATNDKPYSEACAPSILITFIDMVLFNTPKP 647
            ..|:..||:||::||||||.|||.:||.||..: |.|:.:|.:..||||:||.||:|:||...:
  Fly   557 YASIFLEFVPQILFLLLLFGYMVFMMFFKWFSYNARTSFQPETPGCAPSVLIMFINMMLFKNTE- 620

  Fly   648 PPENCETYMFMGQHFIQVLFVLVAVGCIPVMLLAKPLLIMQARKQ-----------ANVQPIAGA 701
            ||:.|..:||..|..:|..|||:|:.|||.|||.|||.|...||.           .|::...|.
  Fly   621 PPKGCNEFMFESQPQLQKAFVLIALCCIPWMLLGKPLYIKFTRKNKAHANHNGQLTGNIELAEGE 685

  Fly   702 TSDAEAGGVSNSGSHGGGGGHEEEEELSEIFIHQSIHTIEYVLGSVSHTASYLRLWALSLAHAQL 766
            | ....|...|..:.||..|| ::|.:|||:|||:||||||||.::|||||||||||||||||||
  Fly   686 T-PLPTGFSGNEENAGGAHGH-DDEPMSEIYIHQAIHTIEYVLSTISHTASYLRLWALSLAHAQL 748

  Fly   767 AEVLWTMVLSIGLKQEGPVGGIVLTCVFAFWAILTVGILVLMEGLSAFLHTLRLHWVEFQSKFYK 831
            :||||.||||:|||..|..|.|.|..:|..|.:.|:.||||||||||||||||||||||.||||:
  Fly   749 SEVLWQMVLSLGLKMSGVGGAIGLFIIFGAWCLFTLAILVLMEGLSAFLHTLRLHWVEFMSKFYE 813

  Fly   832 GQGYAFQPFSFDAIIE 847
            |.|||||||||.||::
  Fly   814 GMGYAFQPFSFKAILD 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-1	NP_651672.1	V_ATPase_I	27..842	CDD:460232	480/828 (58%)
Vha100-2	NP_650722.1	V_ATPase_I	27..824	CDD:460232	480/828 (58%)