Protein Alignment Vha100-1 and Vha100-4

DIOPT Version :10

• Sequence 1: NP_651672.1
• Gene: Vha100-1 / 43442
• FlyBaseID: FBgn0028671
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_650720.1
• Gene: Vha100-4 / 42214
• FlyBaseID: FBgn0038613
• Length: 844
• Species: Drosophila melanogaster
• Alignment Length: 856
• Identity: 450/856 - (52%)
• Similarity: 585/856 - (68%)
• Gaps: 44/856 - (5%)

  Fly     3 SLFRSEEMALCQLFLQSEAAYACVSELGELGLVQFRDLNPDVNAFQRKFVNEVRRCDEMERKLRY 67
            |:||||.|:|.|::||.||||..::.|||:|.|||||||..:||.||||:.|||||||:||::||
  Fly    15 SIFRSEVMSLVQMYLQPEAAYDTIAALGEVGCVQFRDLNAKINAQQRKFIGEVRRCDELERRIRY 79

  Fly    68 LEKEIKKDGIPMLD-TGESPEAPQPREMIDLEATFEKLENELREVNQNAEALKRNFLELTELKHI 131
            :..|:.|:|..:|| ..:.|.||||||:||||...||.|.|:.|:..|...|:.::|||:|:..:
  Fly    80 VTAELNKEGHKVLDLMDDFPPAPQPREIIDLELHLEKTETEILELAANNVNLQTSYLELSEMIQV 144

  Fly   132 LRKTQVFFDESVPTVYKSSGAYSSSKYRRYPQMADNQNEDEQAQLLGEEGVRASQPGQNLKLGFV 196
            |.:|..||.:.                       ::.|.|     |.:.|........|..||||
  Fly   145 LERTDQFFSDQ-----------------------ESHNFD-----LNKMGTHRDPEKSNGHLGFV 181

  Fly   197 AGVILRERLPAFERMLWRACRGNVFLRQAMIETPLEDPTNGDQVHKSVFIIFFQGDQLKTRVKKI 261
            ||||.|||..||||||||..|||||:|:..::..|.||..|:.:|||||::|||||||:.|::|:
  Fly   182 AGVISREREYAFERMLWRISRGNVFVRRCDVDVALTDPKTGNVLHKSVFVVFFQGDQLQARIRKV 246

  Fly   262 CEGFRATLYPCPEAPADRREMAMGVMTRIEDLNTVLGQTQDHRHRVLVAAAKNLKNWFVKVRKIK 326
            |.||.|.:||||.:.::|:||...|.||:|||..::.||.|||..||.||.|.|..|...|:|:|
  Fly   247 CTGFHAHMYPCPSSHSERQEMVKNVRTRLEDLQVIINQTSDHRTCVLQAALKQLPTWSAMVKKMK 311

  Fly   327 AIYHTLNLFNLDVTQKCLIAECWVPLLDIETIQLALRRGTERSGSSVPPILNRMQTFENPPTYNR 391
            .|||||||||:|:..||||.|.|||..::|.:::||..|:...||:||..:|.:.|.:.|||:.|
  Fly   312 GIYHTLNLFNVDLGSKCLIGEGWVPKRELELVEVALAAGSASVGSTVPSFINVLDTKKEPPTHFR 376

  Fly   392 TNKFTKAFQALIDAYGVASYREMNPAPYTIITFPFLFAVMFGDLGHGAIMALFGLWMIRKEKGLA 456
            |||||:.||.||||||:|.|||:||..||.|||||||||||||:|||.|:.|.||||:..||.|
  Fly   377 TNKFTRGFQNLIDAYGIAGYREVNPGLYTCITFPFLFAVMFGDMGHGTILFLLGLWMVIDEKRL- 440

  Fly   457 AQKTDNEIWNIFFGGRYIIFLMGVFSMYTGLIYNDIFSKSLNIFGSHWHLSYNKSTVMENKFLQL 521
            ::|...|||||||.|||||.|||:|:||||..||||||||:|:||:.|...||::||:.|..|||
  Fly   441 SKKRGGEIWNIFFAGRYIIMLMGLFAMYTGFHYNDIFSKSINVFGTRWVNVYNRTTVLTNPTLQL 505

  Fly   522 SPKGDYEGAPYPFGMDPIWQVAGANKIIFHNAYKMKISIIFGVIHMIFGVVMSWHNHTYFRNRIS 586
            :|.....|. ||.|:|||||.| :|||||.|.||||:||||||:||:|||.||..|..:|:....
  Fly   506 NPSVATRGV-YPMGIDPIWQSA-SNKIIFLNTYKMKLSIIFGVLHMVFGVCMSVENFVFFKKYAY 568

  Fly   587 LLYEFIPQLVFLLLLFFYMVLLMFIKWIKFAATND-KPYSEACAPSILITFIDMVLFNTPKPPPE 650
            ::.:|:||::||||:|.||..:||.||:|::.|.| :..:..||||:||.|||||||.|....|
  Fly   569 IILQFVPQVLFLLLMFGYMCFMMFYKWVKYSPTTDVEADTPGCAPSVLIMFIDMVLFKTETALP- 632

  Fly   651 NCETYMFMGQHFIQVLFVLVAVGCIPVMLLAKPLLIMQARKQANVQPIAGATSDAEAGGVSN--- 712
            .|:..||..|..::::|::||:.|||.:||.|||.|...|:.....|:.......|...|:.
  Fly   633 GCDVNMFPIQKNLEMIFLVVALLCIPWILLGKPLYIKYQRRNRPAGPVEEVDEIVEKIEVTTGKE 697

  Fly   713 ------SGSHGGGGGHEEEEE-LSEIFIHQSIHTIEYVLGSVSHTASYLRLWALSLAHAQLAEVL 770
                  :.:|..||..||::| :|||:|||:||||||:|.::|||||||||||||||||||:|||
  Fly   698 IIITEVAEAHESGGHSEEDDEPMSEIWIHQAIHTIEYILSTISHTASYLRLWALSLAHAQLSEVL 762

  Fly   771 WTMVLSIGLKQEGPVGGIVLTCVFAFWAILTVGILVLMEGLSAFLHTLRLHWVEFQSKFYKGQGY 835
            |||||::||:..|.||.|.|..:||.|...|:.|:|:||||||||||||||||||.||||.|.||
  Fly   763 WTMVLAMGLQMNGYVGAIGLFFIFAVWEFFTIAIMVMMEGLSAFLHTLRLHWVEFMSKFYVGNGY 827

  Fly   836 AFQPFSFDAII 846
            .|.||||..|:
  Fly   828 PFTPFSFKDIL 838

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-1	NP_651672.1	V_ATPase_I	27..842	CDD:460232	433/826 (52%)
Vha100-4	NP_650720.1	V_ATPase_I	39..834	CDD:460232	433/826 (52%)