Protein Alignment Vha100-1 and Vha100-3

DIOPT Version :9

• Sequence 1: NP_651672.1
• Gene: Vha100-1 / 43442
• FlyBaseID: FBgn0028671
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_725837.1
• Gene: Vha100-3 / 246543
• FlyBaseID: FBgn0028669
• Length: 904
• Species: Drosophila melanogaster
• Alignment Length: 928
• Identity: 342/928 - (36%)
• Similarity: 484/928 - (52%)
• Gaps: 131/928 - (14%)

  Fly     3 SLFRSEEMALCQLFLQSEAAYACVSELGELGLVQFRDLNPDVNAFQRKFVNEVRRCDEMERKLRY 67
            |.||||:|.||||.|.:|.|:.|:.|:|..|.|||.::..:.......:..:|.:|.|:.|.:..
  Fly    13 SFFRSEDMDLCQLLLHTENAFDCLIEVGHHGAVQFNNVYDEDRLLNNLYSKKVTQCYELLRIVDS 77

  Fly    68 LEKEIKKDGIPMLDTGESPEAPQPREMIDLEATFEKLENELREVNQNAEALKRNFLELTE----- 127
            |...|.:     |...|.......||....|....|..:.|:.::..|.|:..::..|..
  Fly    78 LHTYIVQ-----LHVNEIFYPDVDRENRLKEKDLAKYSDSLKRIHVEASAVTEHYYRLDSRRNRM 137

  Fly   128 LKH--ILRK----------TQVFFDES-----VPTVYKSSGAYSSSKYRRYPQMADNQNEDEQAQ 175
            ::|  .|.|          :::.:.||     |.....:||||.:
  Fly   138 MEHSFALNKANKYMVSDMGSELLYSESTVIGLVQDATTTSGAYPA-------------------- 182

  Fly   176 LLGEEGVRASQPGQNLKLGFVAGVILRERLPAFERMLWRACRGNVFLRQAMIETPLEDPTNG--- 237
                            .|.::.|.|..::..:||.:|:|.|..|:.:|.:.:.:|:.:...|
  Fly   183 ----------------HLNYMIGCIRADKFYSFELLLYRLCSFNLIIRFSEMPSPVYEYHYGYKP 231

  Fly   238 DQVHKSVFIIFFQGDQLKTRVKKICEGFRATLYPCPEAPADRREMAMGVMTRIEDLNTVLGQTQD 302
            ::|.|...::......:..:|.|||..:...:|.||.:.:.|.:....:...|.::..||.:.:.
  Fly   232 ERVRKFAILMMASSTMIWPKVLKICAHYHVNIYDCPSSASQREDKVKELSQEIVNVEKVLKEAEL 296

  Fly   303 HRHRVLVAAAKNLKNWFVKVRKIKAIYHTLNLFNL----DVTQKCLIAECWVPLLDIETIQLALR 363
            .|.::|..|.::|....|.:||...:|..:|...|    :| .:.|:||.::|..|:..:::.||
  Fly   297 MRRQILEVAGRDLFIIRVNLRKALKVYDLMNRLRLVGGVEV-PRYLLAEVYIPSSDVPEVEVILR 360

  Fly   364 RGTERSG------SSVPPILNRMQTFEN--------------------------------PPTYN 390
            ..:..||      ||....:|.|:|..|                                ||||.
  Fly   361 NASRISGGADNIDSSDEDEMNDMKTMPNTTPYPIEADFQPLEDMSAGAILLKKNRLVNHMPPTYF 425

  Fly   391 RTNKFTKAFQALIDAYGVASYREMNPAPYTIITFPFLFAVMFGDLGHGAIMALFGLWMIRK---- 451
            |.||||:.||.||||||:|.|:|:||||||||||||||||||||||||.::.||...||.|
  Fly   426 RLNKFTRGFQNLIDAYGMADYKELNPAPYTIITFPFLFAVMFGDLGHGILLILFSSLMIWKHREI 490

  Fly   452 EKGLAAQKTDNEIWNIFFGGRYIIFLMGVFSMYTGLIYNDIFSKSLNIFGSHWHLSYNKSTVMEN 516
            ||......::|||.||.:.|||||.||||||:|.||:||.:.:|..|:|||.|...||::||.:.
  Fly   491 EKYQINATSENEILNILYAGRYIILLMGVFSVYMGLVYNIVMAKGFNLFGSSWSCRYNETTVYDP 555

  Fly   517 KF---LQLSPKGDYEGAPYPFGMDPIWQVAGANKIIFHNAYKMKISIIFGVIHMIFGVVMSWHNH 578
            .|   |..|....|.|.|||.||||:|.|.|.:.|...|:.|||::|:.|:..|:||:.::..|.
  Fly   556 AFHVTLDSSHPHFYSGHPYPLGMDPVWAVCGQDSITTTNSLKMKMAIVLGISQMMFGLGLAAANC 620

  Fly   579 TYFRNRISLLYEFIPQLVFLLLLFFYMVLLMFIKWIKFAATNDKPYSEACAPSILITFIDMVLFN 643
            .....:..|:...|||::|:|.||.|:|.|:|.||:.:......||:.|||||:|||||:|:|..
  Fly   621 VLMNRKADLILVVIPQMIFMLCLFGYLVFLIFYKWMSYGGHKPAPYNAACAPSVLITFINMMLMK 685

  Fly   644 TPKPPPENCETYMFMGQHFIQVLFVLVAVGCIPVMLLAKPLLIMQAR-----------KQANVQP 697
             .:.|.|||..||:..:..|:...|.:|...||::|..||:.:|:.|           |:...|.
  Fly   686 -KEDPVENCLDYMYPNERMIEFALVGIAFCTIPILLAGKPIYLMRRRRKMQQERERDFKRMRRQT 749

  Fly   698 IAGATSDAEAGGVSNS-GSHGGGGGHEEEEELSEIFIHQSIHTIEYVLGSVSHTASYLRLWALSL 761
            ||...|........|| .|......:|||.|:|||:||..|||||.|||||||||||||||||||
  Fly   750 IAEMRSTMRYTDDDNSETSRQKSVDNEEEHEMSEIWIHSGIHTIETVLGSVSHTASYLRLWALSL 814

  Fly   762 AHAQLAEVLWTMVLSIGLKQEGPV--GGIVLTCVFAFWAILTVGILVLMEGLSAFLHTLRLHWVE 824
            ||.||::|||.|||:.|.....|:  |..||...|..||||||.|||:|||||||||||||||||
  Fly   815 AHDQLSDVLWHMVLTKGFANTLPLYYGVPVLMATFFAWAILTVAILVMMEGLSAFLHTLRLHWVE 879

  Fly   825 FQSKFYKGQGYAFQPFSF 842
            |||||:.|.|.:|:.|:|
  Fly   880 FQSKFFGGAGESFKAFNF 897

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-1	NP_651672.1	NtpI	27..842	CDD:224188	327/902 (36%)
		V_ATPase_I	28..842	CDD:279793	327/901 (36%)
Vha100-3	NP_725837.1	V_ATPase_I	38..897	CDD:279793	327/901 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451294
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1269
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S598
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D164762at33208
OrthoFinder	1	1.000	-	-		FOG0000328
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100301
Panther	1	1.100	-	-	P	PTHR11629
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.700