Protein Alignment Vha100-1 and unc-32

DIOPT Version :10

• Sequence 1: NP_651672.1
• Gene: Vha100-1 / 43442
• FlyBaseID: FBgn0028671
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_001023017.1
• Gene: unc-32 / 176257
• WormBaseID: WBGene00006768
• Length: 905
• Species: Caenorhabditis elegans
• Alignment Length: 896
• Identity: 504/896 - (56%)
• Similarity: 635/896 - (70%)
• Gaps: 53/896 - (5%)

  Fly     4 LFRSEEMALCQLFLQSEAAYACVSELGELGLVQFRDLNPDVNAFQRKFVNEVRRCDEMERKLRYL 68
            ::|||:|.|.||:|||:|:|.||:|||||||||||||||||::||||:|||||||||||||||||
 Worm    16 IYRSEQMCLAQLYLQSDASYQCVAELGELGLVQFRDLNPDVSSFQRKYVNEVRRCDEMERKLRYL 80

  Fly    69 EKEIKKDGIPMLDTGESPEAPQPREMIDLEATFEKLENELREVNQNAEALKRNFLELTELKHILR 133
            |:|||||.||||||||:|:||.||||||||||||||||||||||:|.|.||:||.||||||||||
 Worm    81 EREIKKDQIPMLDTGENPDAPLPREMIDLEATFEKLENELREVNKNEETLKKNFSELTELKHILR 145

  Fly   134 KTQVFFDESVPTVYK----SSG--AYSSSKYRRYPQMADNQNEDEQAQLLGEEGVRASQPGQNLK 192
            |||.||:|.....::    .||  ..|:.:....|.:.....:|:.|       .|.|.....|:
 Worm   146 KTQTFFEEVDHDRWRILEGGSGRRGRSTEREETRPLIDIGDMDDDSA-------ARMSAQAAMLR 203

  Fly   193 LGFVAGVILRERLPAFERMLWRACRGNVFLRQAMIETPLEDPTNGDQVHKSVFIIFFQGDQLKTR 257
            ||||||||.|||||||||:||||||||||||.:.|:..|.|...||.|:|.|||||||||.|||:
 Worm   204 LGFVAGVIQRERLPAFERLLWRACRGNVFLRTSEIDDVLNDTVTGDPVNKCVFIIFFQGDHLKTK 268

  Fly   258 VKKICEGFRATLYPCPEAPADRREMAMGVMTRIEDLNTVLGQTQDHRHRVLVAAAKNLKNWFVKV 322
            ||||||||||||||||:.|.:||||::|||||||||.|||||||||||||||||:||::.|..||
 Worm   269 VKKICEGFRATLYPCPDTPQERREMSIGVMTRIEDLKTVLGQTQDHRHRVLVAASKNVRMWLTKV 333

  Fly   323 RKIKAIYHTLNLFNLDVTQKCLIAECWVPLLDIETIQLALRRGTERSGSSVPPILNRMQTFENPP 387
            ||||:|||||||||:||||||||||.|.|:.:::.|::||:|||:.|||.||.|||||:|.|.||
 Worm   334 RKIKSIYHTLNLFNIDVTQKCLIAEVWCPIAELDRIKMALKRGTDESGSQVPSILNRMETNEAPP 398

  Fly   388 TYNRTNKFTKAFQALIDAYGVASYREMNPAPYTIITFPFLFAVMFGDLGHGAIMALFGLWMIRKE 452
            |||:||||||.||.::||||:|:|||:||||||:|:|||||||||||:||||||.|..|:.|.||
 Worm   399 TYNKTNKFTKGFQNIVDAYGIATYREINPAPYTMISFPFLFAVMFGDMGHGAIMLLAALFFILKE 463

  Fly   453 KGLAAQKTDNEIWNIFFGGRYIIFLMGVFSMYTGLIYNDIFSKSLNIFGSHWHLSYNKSTV---- 513
            |.|.|.:..:||:..||||||:|||||.||:|||.:|||:||||:|.|||.|..:..:|.:
 Worm   464 KQLEAARIKDEIFQTFFGGRYVIFLMGAFSIYTGFMYNDVFSKSINTFGSSWQNTIPESVIDYYL 528

  Fly   514 -----MENKFLQLSPKGDYEGAPYPFGMDPIWQVAGANKIIFHNAYKMKISIIFGVIHMIFGVVM 573
                 .|::.: |.|:..::|.|||.|:||:|.:|..||:.|.|:.|||:|::||:..|.|||::
 Worm   529 DDEKRSESQLI-LPPETAFDGNPYPIGVDPVWNLAEGNKLSFLNSMKMKMSVLFGIAQMTFGVLL 592

  Fly   574 SWHNHTYFRNRISLLYEFIPQLVFLLLLFFYMVLLMFIKWIKFAATND-----KPYSEACAPSIL 633
            |:.|..||::.:.:.|.||||::||..:|.|:.:.:..||:.|.|...     |.....||||:|
 Worm   593 SYQNFIYFKSDLDIKYMFIPQMIFLSSIFIYLCIQILSKWLFFGAVGGTVLGYKYPGSNCAPSLL 657

  Fly   634 ITFIDMVLFNTPKP--PPENCETY-------MFMGQHFIQVLFVLVAVGCIPVMLLAKPLLIMQA 689
            |..|:|.:..:...  ..::.|||       .:.||..|:::.|::|:..:|:||.|||..:.:.
 Worm   658 IGLINMFMMKSRNAGFVDDSGETYPQCYLSTWYPGQATIEIILVVLALVQVPIMLFAKPYFLYRR 722

  Fly   690 RKQANVQPIAGATS-------------DAEAGGVSNSGSHGGGGGHEEEE---ELSEIFIHQSIH 738
            .||.:......|.|             |||............|.||...:   |:.::.::|:||
 Worm   723 DKQQSRYSTLTAESNQHQSVRADINQDDAEVVHAPEQTPKPSGHGHGHGDGPLEMGDVMVYQAIH 787

  Fly   739 TIEYVLGSVSHTASYLRLWALSLAHAQLAEVLWTMVLSIGLKQEGPVGGIVLTCVFAFWAILTVG 803
            |||:|||.||||||||||||||||||||::||||||.......:|..|.|....:|..:..|:|.
 Worm   788 TIEFVLGCVSHTASYLRLWALSLAHAQLSDVLWTMVFRNAFVLDGYTGAIATYILFFIFGSLSVF 852

  Fly   804 ILVLMEGLSAFLHTLRLHWVEFQSKFYKGQGYAFQPFSFDAIIENGAAAAE 854
            |||||||||||||.|||||||||||||.|.||.|.||||:.|:.....|.|
 Worm   853 ILVLMEGLSAFLHALRLHWVEFQSKFYGGLGYEFAPFSFEKILAEEREAEE 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-1	NP_651672.1	V_ATPase_I	27..842	CDD:460232	485/859 (56%)
unc-32	NP_001023017.1	V_ATPase_I	39..891	CDD:460232	485/859 (56%)