Protein Alignment Vha100-1 and LOC1281585

DIOPT Version :10

• Sequence 1: NP_651672.1
• Gene: Vha100-1 / 43442
• FlyBaseID: FBgn0028671
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: XP_321519.1
• Gene: LOC1281585 / 1281585
• VectorBaseID: AGAMI1_004174
• Length: 808
• Species: Anopheles gambiae
• Alignment Length: 853
• Identity: 481/853 - (56%)
• Similarity: 612/853 - (71%)
• Gaps: 48/853 - (5%)

  Fly     1 MGSLFRSEEMALCQLFLQSEAAYACVSELGELGLVQFRDLNPDVNAFQRKFVNEVRRCDEMERKL 65
            ||::||||||::.||.:|.||||..|:||||||:.||||||.|:|.||||:.:|:|||:|||||:
Mosquito     1 MGAMFRSEEMSMVQLLIQPEAAYQSVAELGELGIAQFRDLNTDINMFQRKYTSEIRRCEEMERKI 65

  Fly    66 RYLEKEIKKDGIPMLDTGE-SPEAPQPREMIDLEATFEKLENELREVNQNAEALKRNFLELTELK 129
            .|:.:||.||.:.:.|..| .|..|..||:|||||..||.|||:.|:::|..||.:||:||||||
Mosquito    66 GYIRREIVKDSVAIPDMPEVIPRTPNSREIIDLEAQLEKTENEIVELSENNNALLQNFMELTELK 130

  Fly   130 HILRKTQVFFDESVPTVYKSSGAYSSSKYRRYPQMADNQNEDEQAQLLGEEGVRASQPGQNLKLG 194
            |:|.||||||                         :|..|    .|.|...|..|:..|:  .||
Mosquito   131 HVLEKTQVFF-------------------------SDKSN----VQNLEATGGEAANDGK--PLG 164

  Fly   195 FVAGVILRERLPAFERMLWRACRGNVFLRQAMIETPLEDPTNGDQVHKSVFIIFFQGDQLKTRVK 259
            ||||||.|||:..|||||||..|||:|||||.:|..|.||..||.|||.||:.||||:|||.|||
Mosquito   165 FVAGVISRERIIGFERMLWRVSRGNIFLRQATLEESLVDPKTGDSVHKIVFVAFFQGEQLKARVK 229

  Fly   260 KICEGFRATLYPCPEAPADRREMAMGVMTRIEDLNTVLGQTQDHRHRVLVAAAKNLKNWFVKVRK 324
            |:|.|:.|:|||||....:|.||..||.||||||..|||||||.|.|||:..||.:.||.:.|:|
Mosquito   230 KVCAGYHASLYPCPNEYNEREEMLRGVRTRIEDLKMVLGQTQDQRQRVLLNVAKEVPNWEIIVKK 294

  Fly   325 IKAIYHTLNLFNLDVTQKCLIAECWVPLLDIETIQLALRRGTERSGSSVPPILNRMQTFENPPTY 389
            :||||||||:||:||::|||..|.|||...::.::.||..|:...||:||..||.:.|.|:||||
Mosquito   295 VKAIYHTLNMFNVDVSKKCLFGEAWVPTAGLQDVKTALVNGSAAVGSAVPSFLNIIATDEDPPTY 359

  Fly   390 NRTNKFTKAFQALIDAYGVASYREMNPAPYTIITFPFLFAVMFGDLGHGAIMALFGLWMIRKEKG 454
            |:|||||:.||.||::||:|:|||.|||.|||||||||||:||||||||.|:.|.|:||:..||.
Mosquito   360 NKTNKFTRGFQNLIESYGIATYREANPALYTIITFPFLFAIMFGDLGHGLILFLLGMWMVLWEKT 424

  Fly   455 LAAQKTDNEIWNIFFGGRYIIFLMGVFSMYTGLIYNDIFSKSLNIFGSHWHLSYNKSTVMENKFL 519
            |  .|...|||.:||||||||.|||:||||||.:|||:|||.:|||||.|.::||.||||.||.|
Mosquito   425 L--DKNKEEIWQLFFGGRYIILLMGIFSMYTGFVYNDVFSKGMNIFGSAWSVNYNTSTVMTNKEL 487

  Fly   520 QLSPKGDYEGAPYPFGMDPIWQVAGANKIIFHNAYKMKISIIFGVIHMIFGVVMSWHNHTYFRNR 584
            ||:|..||....|.:|:||:|.:| .|||||.|::|||:||||||:||||||.||..||.:|..|
Mosquito   488 QLNPTTDYSETVYWYGLDPLWMLA-TNKIIFLNSFKMKLSIIFGVVHMIFGVCMSLVNHNHFNRR 551

  Fly   585 ISLLYEFIPQLVFLLLLFFYMVLLMFIKWIKFAATNDKPY-SEACAPSILITFIDMVLFNTPKPP 648
            :::|.|||||::||:|||.||..:||.|||.::|..|:.: ...||||:||.||:|:||.. :.|
Mosquito   552 VNILLEFIPQMMFLVLLFAYMCFMMFFKWIMYSAVTDEDHLKPGCAPSVLIMFINMMLFKN-QEP 615

  Fly   649 PENCETYMFMGQHFIQVLFVLVAVGCIPVMLLAKPLLIMQARKQANVQPIAGATSDAEAGGVSNS 713
            .:.|:.:||.||..:||:|:::.:.|||.:|||||..||..||..:.:      ..:|....|:|
Mosquito   616 LDTCKEFMFEGQDTLQVIFIVLGLICIPWLLLAKPFYIMFKRKGKSTE------HGSEVAHQSSS 674

  Fly   714 GSHGGGGGHEEEEELSEIFIHQSIHTIEYVLGSVSHTASYLRLWALSLAHAQLAEVLWTMVLSIG 778
            .|:     |.::|.:|||||||:||||||:|.::|||||||||||||||||||:|||:.||.:||
Mosquito   675 SSN-----HHDDEPMSEIFIHQAIHTIEYILSTISHTASYLRLWALSLAHAQLSEVLYNMVFTIG 734

  Fly   779 LKQEGPVGGIVLTCVFAFWAILTVGILVLMEGLSAFLHTLRLHWVEFQSKFYKGQGYAFQPFSFD 843
            |:.:..||.|::..||..|::||:||||.||||||||||||||||||.||||:|.||||:||||.
Mosquito   735 LRNDSYVGAIMIWLVFWPWSVLTIGILVGMEGLSAFLHTLRLHWVEFMSKFYEGLGYAFKPFSFK 799

  Fly   844 AIIENGAA 851
            ||:|...|
Mosquito   800 AILEEEEA 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-1	NP_651672.1	V_ATPase_I	27..842	CDD:460232	459/816 (56%)
LOC1281585	XP_321519.1	V_ATPase_I	27..798	CDD:460232	459/816 (56%)