Protein Alignment Vha100-1 and Atp6v0a2

DIOPT Version :9

• Sequence 1: NP_651672.1
• Gene: Vha100-1 / 43442
• FlyBaseID: FBgn0028671
• Length: 855
• Species: Drosophila melanogaster
• Sequence 2: NP_446227.2
• Gene: Atp6v0a2 / 116455
• RGDID: 621006
• Length: 856
• Species: Rattus norvegicus
• Alignment Length: 886
• Identity: 400/886 - (45%)
• Similarity: 563/886 - (63%)
• Gaps: 82/886 - (9%)

  Fly     1 MGSLFRSEEMALCQLFLQSEAAYACVSELGELGLVQFRDLNPDVNAFQRKFVNEVRRCDEMERKL 65
            ||||||||.|.|.||||||..||.|:|.|||.|||||||||.:|::||||||.||:||:|:||.|
  Rat     1 MGSLFRSESMCLAQLFLQSGTAYECLSALGEKGLVQFRDLNQNVSSFQRKFVGEVKRCEELERIL 65

  Fly    66 RYLEKEIKKDGIPMLDTGESPEAPQPREMIDLEATFEKLENELREVNQNAEALKRNFLELTELKH 130
            .||.:||.:..||:.:...||.||..:.:::::...:|||.|||||.:|.|.|::|.|||.|..|
  Rat    66 VYLVQEITRADIPLPEGEASPPAPPVKHVLEMQEQLQKLEVELREVTKNKEKLRKNLLELVEYTH 130

  Fly   131 ILRKTQVFFDESV---PTVYKSSGAYSSSKYRRYPQM-ADNQNEDEQAQLLGEEGVRASQPGQNL 191
            :||.|:.|...:|   ||            |..:|.: :|:..:....|.||            .
  Rat   131 MLRVTKTFLKRNVEFEPT------------YEEFPALESDSLLDYSCMQRLG------------A 171

  Fly   192 KLGFVAGVILRERLPAFERMLWRACRGNVFLRQAMIETPLEDPTNGDQVHKSVFIIFFQGDQLKT 256
            |||||:|:|.:.::.||||||||||:|...:..|.::..||||..|:.:...||:|.|.|:|:..
  Rat   172 KLGFVSGLIQQGKVEAFERMLWRACKGYTIVTYAELDEALEDPETGEVIKWYVFLISFWGEQIGH 236

  Fly   257 RVKKICEGFRATLYPCPEAPADRREMAMGVMTRIEDLNTVLGQTQDHRHRVLVAAAKNLKNWFVK 321
            :|||||:.:...:||.|....:|||:..|:.|||:||.|||.:|:|:..:||..||:::.:..::
  Rat   237 KVKKICDCYHCHIYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVCSRVIQ 301

  Fly   322 VRKIKAIYHTLNLFNLDVTQKCLIAECWVPLLDIETIQLALRRGTERSGSSVPPILNRMQTFENP 386
            |||:|||||.||:.:.|||.||||||.|.|.:|:..::.||..|:..||:::|..:|.:.|.|.|
  Rat   302 VRKMKAIYHMLNMCSFDVTNKCLIAEVWCPEVDLPGLRRALEEGSRESGATIPSFMNTIPTKETP 366

  Fly   387 PTYNRTNKFTKAFQALIDAYGVASYREMNPAPYTIITFPFLFAVMFGDLGHGAIMALFGLWMIRK 451
            ||..||||||:.||.::|||||.||||:|||.:|||||||||.|||||||||.:|.||.|.::..
  Rat   367 PTLIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITFPFLFGVMFGDLGHGFVMFLFALLLVLN 431

  Fly   452 EKGLAAQKTDNEIWNIFFGGRYIIFLMGVFSMYTGLIYNDIFSKSLNIFGSHWHLS--------- 507
            |......:: .||..:||.||||:.|||:||:||||||||.||||||:|||.|::|
  Rat   432 ENHPRLSQS-QEILRMFFDGRYILLLMGLFSVYTGLIYNDCFSKSLNLFGSGWNVSAMYSSSHSP 495

  Fly   508 --------YNKSTVMENKFLQLSPK--GDYEGAPYPFGMDPIWQVAGANKIIFHNAYKMKISIIF 562
                    :|.||:..::.|||.|.  |.:.| |||||:||||.:| .|::.|.|::|||:|:|.
  Rat   496 EEQRKMVLWNDSTIRHSRTLQLDPNIPGVFRG-PYPFGIDPIWNLA-TNRLTFLNSFKMKMSVIL 558

  Fly   563 GVIHMIFGVVMSWHNHTYFRNRISLLYEFIPQLVFLLLLFFYMVLLMFIKWIKFAATNDKPYSEA 627
            |:.||.|||::...||.:||.:.::....:|:::|:|.:|.|::.::..||:.::|...:.
  Rat   559 GIFHMTFGVILGIFNHLHFRKKFNIYLVSVPEILFMLCIFGYLIFMIIYKWLAYSAETSRE---- 619

  Fly   628 CAPSILITFIDMVLFNTPKPPPENCETY-MFMGQHFIQVLFVLVAVGCIPVMLLAKPLLIM---- 687
             ||||||.||:|.||       .:.||: ::.||..:|.:.:.:.|..:||:.|.|||.::
  Rat   620 -APSILIEFINMFLF-------PSSETHGLYPGQAHVQKVLLALTVLAVPVLFLGKPLFLLWLHN 676

  Fly   688 -------------QARKQANVQPIAGATSDAEAGGVSNSGSHGGGGGHEEEEELSEIFIHQSIHT 739
                         ..||.:..:.....:.|.|.|  :|....|......||....||.:.|:||:
  Rat   677 GRSCFGVSRSGYTLVRKDSEEEVSLLGSQDIEEG--NNRMEEGCREMTCEEFNFGEILMTQAIHS 739

  Fly   740 IEYVLGSVSHTASYLRLWALSLAHAQLAEVLWTMVLSIGLKQEGPVGGIVLTCVFAFWAILTVGI 804
            |||.||.:|:|||||||||||||||||::|||.|::.:||:.:...|.::|..|..|:|:|||.|
  Rat   740 IEYCLGCISNTASYLRLWALSLAHAQLSDVLWAMLMRVGLRVDNTYGVLLLLPVMTFFAVLTVFI 804

  Fly   805 LVLMEGLSAFLHTLRLHWVEFQSKFYKGQGYAFQPFSFDAI 845
            |::|||||||||.:||||||||:|||.|.|..|.||||..:
  Rat   805 LLVMEGLSAFLHAIRLHWVEFQNKFYVGAGTKFVPFSFSLL 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha100-1	NP_651672.1	NtpI	27..842	CDD:224188	379/855 (44%)
		V_ATPase_I	28..842	CDD:279793	378/854 (44%)
Atp6v0a2	NP_446227.2	NtpI	5..839	CDD:224188	392/874 (45%)
		V_ATPase_I	28..839	CDD:279793	376/851 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D164762at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010