Protein Alignment dgt6 and Haus6

DIOPT Version :9

• Sequence 1: NP_651671.1
• Gene: dgt6 / 43441
• FlyBaseID: FBgn0039638
• Length: 654
• Species: Drosophila melanogaster
• Sequence 2: NP_775576.2
• Gene: Haus6 / 230376
• MGIID: 1923389
• Length: 933
• Species: Mus musculus
• Alignment Length: 757
• Identity: 169/757 - (22%)
• Similarity: 266/757 - (35%)
• Gaps: 259/757 - (34%)

  Fly    44 DMFLKPNQVAFVHVMHYLFRLLDPAEFKRRF--FWPITDKKSEANFRSSTVEYLKHLNEKHQLHW 106
            :||.|.|:.||..|.::||:.||.|..|..|  .||..|:|.:..||....|:||.::.:....:
Mouse    44 NMFDKLNRDAFHIVSYFLFKTLDEALAKEVFRDCWPPFDQKLDMEFRKHCCEWLKEISAECGSSF 108

  Fly   107 ANIKSYLVVMPGGMRFINFLLEFVGFVIQELIKQREKSLGLEAGTPNVS---------------- 155
            ..:...|::.|||.:||:.:..|..:|..:.||.:..:....|.|.||.
Mouse   109 PQVVGSLLMSPGGPKFIHLMYHFARYVAIKYIKTKSNNSLHFAETFNVKPQDMHKCLARSHVARN 173

  Fly   156 --AKVMARQNAVMKEYASSYVVNL---------------------------EENTALLRDKTQKI 191
              .:::.|::.||::|..:  |||                           :.||   ::|.||:
Mouse   174 RFLQILQREHYVMQKYQEN--VNLSVKQVRNARSECMSLQNQIKRMEPYDEKSNT---QEKIQKV 233

  Fly   192 RRLMADLSADMGVPEEQLADD------GFLDEFE---ATAALGVERVITQPTERKFDLEASLCGL 247
            |.|.|.::..:.|.|::  .|      ||::::.   |..|:.:.|::..      .||..:|.|
Mouse   234 RSLWASVNETLMVVEKE--RDVISSLFGFVNQYALDGAHVAVNIPRLLLD------RLEEQICRL 290

  Fly   248 KEAIDLFQVKQAENNQSKEAVEKALRGMRVLFDCDAVTEGDFYDPLGASKMDALLNGFNRISGTI 312
                   |:                              |:.|:   |.|::.|         ||
Mouse   291 -------QI------------------------------GNVYE---AGKLNLL---------TI 306

  Fly   313 AEQLD------ANDHYNESNAFVTTDLQALRVELSQSEVQLNNLLKKLNEPSK------------ 359
            ...|:      ..:|.....|.:|.:|..|..|......:|:: :|.:....|
Mouse   307 IHLLNEVLKIMKYEHCKAGQAGLTINLHYLEKETKFQRERLSH-MKHMRHKVKETVTAVRQSIAD 370

  Fly   360 -------KDKGSANAS-------GSARVQTLQPATP-RFESV--------ISSKFVSTPP----- 396
                   |.||....|       ..|.|..|.|.:| .|:.|        |..|:.::.|
Mouse   371 KEGKWHMKWKGFLGLSPFRLIKDRPAAVDLLPPMSPLTFDPVSEEVYAKSILFKYPASLPDSHKE 435

  Fly   397 --------IRIDMGGG--GGRNAPVRLALQDDFNGKQFDALSNSLLAPAPPRSARKLKALDQSTG 451
                    ..:|..|.  .|.|:||...||   .....|..|::||...|.......|.|...|.
Mouse   436 PKQESGSRREVDTPGSVCDGANSPVPFPLQ---CAASSDTNSSTLLEKDPNMRTPIEKTLTYKTI 497

  Fly   452 ID-------LNGTLNRSKINDPMQMLRTIHKNTSKVKAAPQANLSSLGSKWKQMQASFGFDEAPV 509
            .|       |:.|...|:        .::.:.|..||.:         ..:::.||.. .||.
Mouse   498 ADSEEEDSPLSDTAKNSQ--------SSVSRGTLPVKRS---------EPFQKEQARL-VDEV-- 542

  Fly   510 PGAAVI---SPQTS-----------PTDPSDPFTPLSGSECTRIERIPRTSENNTSLIAKSAAVI 560
              |.|:   |||.|           .|..|:||       .|| ::||||.||..:.|..|..
Mouse   543 --ARVVLSDSPQLSERKEVELEELIDTLISNPF-------LTR-KQIPRTPENLITDIRSSWR-- 595

  Fly   561 KVLEVSRNVLNLSTSPSGRL-DALVPHTESHQQDVAPRLQLNDRTINDSLQLDPDFNIENDKNAF 624
            |.:|...|     .|..|.| ||......|.......    |.|..:.:: ..|||    |::.|
Mouse   596 KAVETEDN-----RSSDGILVDASAREVSSESSSTLH----NQREFSLAI-FSPDF----DRSYF 646

  Fly   625 NVSHKFDFDQIGG------------EDDLQNISDSVLKDIIF 654
             ...|...||:.|            |...:::||.|.|.:|:
Mouse   647 -PEEKAVSDQLKGLPQKHLVTSQIREPPTEDVSDLVNKKMIW 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dgt6	NP_651671.1	HAUS6_N	21..257	CDD:317106	65/268 (24%)
Haus6	NP_775576.2	HAUS6_N	15..238	CDD:291333	51/198 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850759
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28NJA
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto94858
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR16151
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5331
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.920