Protein Alignment Ctl2 and PNS1

DIOPT Version :10

• Sequence 1: NP_651670.1
• Gene: Ctl2 / 43440
• FlyBaseID: FBgn0039637
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: NP_014804.3
• Gene: PNS1 / 854332
• SGDID: S000005687
• Length: 539
• Species: Saccharomyces cerevisiae
• Alignment Length: 517
• Identity: 98/517 - (18%)
• Similarity: 185/517 - (35%)
• Gaps: 148/517 - (28%)

  Fly   283 YNGTNDAQLLGEKIVEDLVNSWSIVLVACFCTLVASLIYIALMRWLSAPILWFSIFGVLIGLLVG 347
            |:|.|...|        ..|:..:::..|...||.|::.:.|.|......::   .|::|.|:..
Yeast   117 YDGVNTGTL--------NTNAAILLVFVCIIALVFSVLGLTLCRIFPKQFIY---CGMVINLVAS 170

  Fly   348 I-----YFSVKQYIHWENTPTVPVHGLNLHSTVKNVLQNQNTWLYLSIFVGVCFVVILLLVI--- 404
            :     |.|::   :|.                                .|:.|:|...:..
Yeast   171 LGTAIMYMSLR---YWS--------------------------------AGIVFLVFTFMTAWCY 200

  Fly   405 -VLRKRIRIAIALTKEGSKAVSSVISTVFFPIFSWILFIAAIAF---AIGVGLYLGSIGDPSFRM 465
             .:|.||.:::|:.|....|:.. ...:||..|...|..:|..|   |:.|..|:..  ||:
Yeast   201 WGMRSRIPLSVAVLKVVVDAMKK-CPQIFFVSFVGALVASAFGFLFSAVIVATYIKY--DPN--- 259

  Fly   466 VRQLTKSGEVTTEDCVCEGPAINYTVGGSCKPEVFQQYCSVRLTSFFQNRNPCLNTTCSFDSINN 530
                :.:|.       |:      ..||||.   ..:...|.:..||          |.:
Yeast   260 ----SSNGG-------CD------VSGGSCS---HSKLIGVLVVVFF----------CGY----- 289

  Fly   531 PIEIKWAIFYNVFGFLWLSFFISAFSYMVLASTFARWYWTFKK-RDVPYFTLTRAFFQTAVYHLG 594
                            ::|..|....:.|::..|..||:..|. :.:|.:....|..:...|..|
Yeast   290 ----------------YISEVIRNVIHCVISGVFGSWYYMSKSDQGMPRWPAFGALKRAMTYSFG 338

  Fly   595 TVAFGSLILAIVRLIRLVLEYI-HEKLKKYDNAVTRAILCCMRCFFWLLETFLKFL----NRNAY 654
            ::.||||::|::.|:|.:|:.| |:........:  ||......|.|:: .|||:|    |..||
Yeast   339 SICFGSLLVALIDLLRQILQMIRHDVTSSGGGQI--AIQILFMVFDWII-GFLKWLAEYFNHYAY 400

  Fly   655 IMCAIHGKNFCSSAADSFNLIMRNFLRVVTLDQVTDFLFFLSKLLLTAGAGASTYYFL------- 712
            ...|::||.:..:|.:::.::....:..:..|.:.:....|..:..:......|:.:|
Yeast   401 SFIALYGKPYLRAAKETWYMLREKGMDALINDNLINIALGLFSMFASYMTALFTFLYLRFTSPQY 465

  Fly   713 DNNPS----------IIRLNYIAVPTTVV--VIAAFLIT-----SVFFGVYSTAVDTLFLCF 757
            ::|.:          :|.|....:.|..:  ..|.|.:.     .||...|....|.:|..:
Yeast   466 NSNGAYNGALMAFSFVIALQICNIATEAIRSGTATFFVALGNDPEVFHHSYPHRFDEIFRAY 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl2	NP_651670.1	Choline_transpo	407..762	CDD:461337	78/384 (20%)
PNS1	NP_014804.3	Choline_transpo	187..510	CDD:461337	75/382 (20%)