DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ctl2 and AT3G15380

DIOPT Version :9

Sequence 1:	NP_651670.1	Gene:	Ctl2 / 43440	FlyBaseID:	FBgn0039637	Length:	796	Species:	Drosophila melanogaster
Sequence 2:	NP_566511.1	Gene:	AT3G15380 / 820777	AraportID:	AT3G15380	Length:	700	Species:	Arabidopsis thaliana

Alignment Length:	799	Identity:	184/799 - (23%)
Similarity:	324/799 - (40%)	Gaps:	202/799 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QRDRSCTDVPCLLLFVLFLGGWAFIAQYAIRNGDLNKLLVPTDSFNRKCGMDSGVLNKKNLFFFD 90
            :.:|.|.|:..|::|:.|.......:.:....|:..:|....|.....||...   ..::|...:
plant    26 KHNRKCRDITFLIIFIAFWVSMIVNSSFGFNQGNPLRLTYGLDYEGNVCGSKH---RHRDLTQLE 87

  Fly    91 LNQCIDPLVPITGCDTPQVCVETCPRETFVWDT-MKDKQSFAEL---HSRLICLSEEHKAQIRTK 151
            |...::|                    ..|::: :||    .||   ::|.|||.:     ....
plant    88 LRYWLNP--------------------NQVYESGLKD----GELKLANARTICLLD-----CPAP 123

  Fly   152 SDIQDAINQNQCARWYIKSAPFLKRCLFEFSQGVCDYIPSFLLNGGRSRRELH------------ 204
            ||  |.:|      |                  |||| |.     |..|.:::
plant   124 SD--DTLN------W------------------VCDY-PD-----GEIRLKMNDWIDRNYDYFEF 156

  Fly   205 MLPGNATTEVQMQADVMYQKMTDAQALVVPQANGKQTPVDEEPIIQCK---RRLNEAVIKEKMM- 265
            :.|....:.:|:|.        ....::.|..|         ....|:   |..|.::...:.|
plant   157 LTPEMRNSSLQLQG--------PCYPVIFPSVN---------VYWSCQYIARASNSSLRHWQQMG 204

  Fly   266 ----QTDTRLAKLVGNMVAHFYNGTNDAQLLGEKIVEDLVNSWSIVLVAC--FCTLVASLIYIAL 324
                |.|..:.|.:...:       |....:.::.|.|:..||. ||:.|  ...|..|:|::.|
plant   205 GVNIQEDMIIDKSIRRSM-------NSRASVLKRYVADIGKSWP-VLIVCGGLVPLFLSIIWLLL 261

  Fly   325 MRWLSAPILWFSI--FGVLIGLLVGIYFSVKQYIHW-----------ENTPTVPVHGLNLHSTVK 376
            :|...|.:.|.::  |.:|: :.|.:::.:|  ..|           |:.|...|:|..| :.|:
plant   262 IRHFVAAMPWITVVLFNMLL-ISVTVFYYLK--AGWIGNDAVTPIIGEHDPYFHVYGREL-THVR 322

  Fly   377 NVLQNQNTWLYLSIFVGVCFVVILLLVIVLRKRIRIAIALTKEGSKAVSSVISTVFFPIFSWILF 441
            .|          :|.:....||.:|..|.:.:||.:|.::.|..:|.:..|.:.:.||...:.:.
plant   323 GV----------AILMTFISVVAILTSIAIIRRILMATSVLKVAAKVIGEVQALIIFPAIPFAML 377

  Fly   442 IAAIAFAIGVGLYLGSIGDPSFRMVRQLTKSGEVTTEDCVCEGPAINYTVGGSCKPEVFQQYCSV 506
            .....|.|...|:|.|              ||:|...:|       |.|   :|        |:.
plant   378 AIFYMFWISAALHLFS--------------SGQVVQNNC-------NNT---NC--------CAY 410

  Fly   507 RLTSFFQNRNPCLNTTCSFDSINNPIEIKWAIFYNVFGFLWLSFFISAFSYMVLASTFARWYWTF 571
            .|.....|.:.|    |.: ||:....|..|||:::||..|.:.|..|.|..|:|.:.|.:||..
plant   411 DLVLKKVNCDRC----CGY-SIHYTPHITIAIFFHLFGCYWATQFFIASSATVIAGSVASYYWAQ 470

  Fly   572 KKR--DVPYFTLTRAFFQTAVYHLGTVAFGSLILAIVRLIRLVLEYIHEKLK-----------KY 623
            .:.  ::|:..:..:..:.|.|:||:||.||||::.|..:|.:||.|..|.|           :.
plant   471 GEASPEIPFLPVFASMKRLARYNLGSVALGSLIVSFVESVRFILEAIRRKTKVSGTIPDHWFWRM 535

  Fly   624 DNAVTRAILCCMRCFFWLLETFLKFLNRNAYIMCAIHGKNFCSSAADSFNLIMRNFLRVVTLDQV 688
            .:..:|.   |::...|.    :|.:|||||||.||.||:||.|:|.:..||:.|.||:..::.:
plant   536 AHYTSRG---CLKSVEWT----IKSVNRNAYIMIAITGKSFCKSSAIATELIISNILRIGKVNVI 593

  Fly   689 TDFLFFLSKLLLTAGAGASTYYFLDNNPSIIRLNYIAVPTTVVVIA---AFLITSVFFGVYSTAV 750
            .|.:.||.||.::..:....:..||::......|.::.|...|:..   .:::.::||.|...::
plant   594 GDVILFLGKLCVSLFSALFGFLMLDSHRYRASHNKVSSPLLPVLACWALGYIVATLFFAVVEMSI 658

  Fly   751 DTLFLCFLEDCERNDGSPE 769
            ||:.|.|.:|.|.|.|:.:
plant   659 DTIILSFCQDSEENQGNAQ 677

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ctl2	NP_651670.1	Choline_transpo	407..761	CDD:282384	101/369 (27%)
AT3G15380	NP_566511.1	Choline_transpo	326..668	CDD:309592	106/385 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	137	1.000	Domainoid score	I1587
eggNOG	1	0.900	-	-		E1_KOG1362
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1549
OMA	1	1.010	-	-		QHG53694
OrthoDB	1	1.010	-	-		D329225at2759
OrthoFinder	1	1.000	-	-		FOG0000381
OrthoInspector	1	1.000	-	-		otm3077
orthoMCL	1	0.900	-	-		OOG6_100798
Panther	1	1.100	-	-	O	PTHR12385
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X515
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840