Protein Alignment Ctl2 and slc44a5b

DIOPT Version :10

• Sequence 1: NP_651670.1
• Gene: Ctl2 / 43440
• FlyBaseID: FBgn0039637
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: XP_068079072.1
• Gene: slc44a5b / 558142
• ZFINID: ZDB-GENE-081105-4
• Length: 749
• Species: Danio rerio
• Alignment Length: 812
• Identity: 271/812 - (33%)
• Similarity: 409/812 - (50%)
• Gaps: 114/812 - (14%)

  Fly    12 GEPLRYDRNFTGPRQRDRSCTDVPCLLLFVLFLGGWAFIAQYAIRNGDLNKLLVPTDSFNRKCG- 75
            |||.::|..|.||..: |.||||.|.::||:.:.|:..:...|..:||..|::.||||:.:.||
Zfish    14 GEPHKFDPTFRGPVHK-RGCTDVLCCVIFVIVILGYIVLGTVAWMHGDPRKVVYPTDSYGQFCGQ 77

  Fly    76 MDSGVLNKKNLFFFDLNQCIDPLVPIT-GCDTPQVCVETCPRE--TFV---WDTMKDKQSFAELH 134
            .::...||..||:|::.||.:|.|.|. .|.|.|:||..||..  |::   :...::|.|:
Zfish    78 QETPNANKAILFYFNILQCANPSVLINLQCPTTQLCVSKCPDRFATYIDMQYSYRRNKGSW---- 138

  Fly   135 SRLICLSEEHKAQI------RTKSDIQDAINQNQCARWYIKSAPFLKRCLFEFSQGVCDYIPSFL 193
                    |:..|.      .....|...:....|....:.|.|||:||           .|.|:
Zfish   139 --------EYYKQFCKPGFNNPDKPISQVLRDEDCPSMIVPSRPFLQRC-----------FPDFI 184

  Fly   194 LNGGRSRRELHMLPGNATTEVQMQADVMYQKMTDAQALVVPQANGK-QTPVDEEPIIQCKRRLNE 257
            ...|                          .:|.|........:|| ::.||.....:.:|.:..
Zfish   185 TRNG--------------------------TLTVANQTSFKDGHGKIRSVVDLRDAAKQERTVLS 223

  Fly   258 AVIKEKMMQTDTRLAKLVGNMVAHFYNGTNDAQLLGEKIVEDLVNSWSIVLVACFCTLVASLIYI 322
            ..:......|::.:..|:            ||:.:|.||.||..:||..:|:....:::.||::|
Zfish   224 GKVTAMQQGTESGITSLL------------DAKEVGTKIFEDYASSWFWILIGLVISMLVSLVFI 276

  Fly   323 ALMRWLSAPILWFSIFGVLIGLLVGIYFSVKQYIHWENTP--TVPVHGLNLHSTVKNVLQNQNTW 385
            .|:|:.:..:.|..||||:..:..||:....:|...:..|  .|.:..:...:..:..||...||
Zfish   277 LLLRFTAGVLFWLVIFGVIAAVGYGIWHCYWEYSSLKGKPDSDVTISDIGFQTDFRVYLQLSQTW 341

  Fly   386 LYLSIFVGVCFVVILLLVIVLRKRIRIAIALTKEGSKAVSSVISTVFFPIFSWILFIAAIAFAIG 450
            |.....:.|...:|:|::|.||.|:||||||.||||||:..::||:|:||.:::|....||:...
Zfish   342 LIFMTSLAVIEAIIILVLIFLRNRVRIAIALLKEGSKAIGCIMSTLFYPIITFLLLALCIAYWAV 406

  Fly   451 VGLYLGSIGDPSFRMVRQLTKSGEVTTEDCVCEGPAINYTVGGSCKPEVFQQYCSVRLTSFFQNR 515
            ..::|.|.|:..::::.        |..||       .|| ..:|.||.|.|....:|
Zfish   407 TAVFLASSGEAVYKVMS--------TLPDC-------KYT-NLTCDPETFSQSNVTKL------- 448

  Fly   516 NPCLNTTCSFDSINNPIEIKWAIFY----NVFGFLWLSFFISAFSYMVLASTFARWYWTFKK-RD 575
              |..:.|:|............||.    |:..||||..|..|.....||..||.:||..:| .|
Zfish   449 --CPGSQCTFAFYGGESLYHRYIFVLQLCNLLVFLWLVNFTIALGQCTLAGAFAAYYWALRKPAD 511

  Fly   576 VPYFTLTRAFFQTAVYHLGTVAFGSLILAIVRLIRLVLEYIHEKLKKYDNAVTRAILCCMRCFFW 640
            :|...|..:|.:...||.|::|||:|||:||:.||::|||:..|||...||.||.:|||::|.||
Zfish   512 IPPCPLASSFGRALRYHTGSLAFGALILSIVQFIRIILEYLDHKLKGAHNAFTRFLLCCLKCCFW 576

  Fly   641 LLETFLKFLNRNAYIMCAIHGKNFCSSAADSFNLIMRNFLRVVTLDQVTDFLFFLSKLLLTAGAG 705
            .||.|:||:|||||||.:|:|||||:||.|:|.|:|||.:||..||:|||||.||.|||::...|
Zfish   577 CLEHFIKFMNRNAYIMISIYGKNFCTSARDAFFLLMRNVMRVAVLDKVTDFLLFLGKLLISGSVG 641

  Fly   706 ASTYYFLDNNPSIIR-----LNYIAVPTTVVVIAAFLITSVFFGVYSTAVDTLFLCFLEDCERND 765
            ...::|......:|:     |||..||...|:..:::|...||.||:..|||||||||.|.|:||
Zfish   642 VLAFFFFTRQIPVIQEEVPSLNYYWVPLLTVIFGSYMIAHGFFNVYAMCVDTLFLCFLLDLEKND 706

  Fly   766 GSPEKPFFMSKQLMKILGKKNNLPPRQ-RRGK 796
            ||..:|::|...|..||.|||...|:: :||:
Zfish   707 GSATRPYYMCSSLRAILNKKNQKRPKETKRGR 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl2	NP_651670.1	Choline_transpo	407..762	CDD:461337	152/364 (42%)
slc44a5b	XP_068079072.1	Choline_transpo	348..703	CDD:461337	157/379 (41%)