Protein Alignment Ctl2 and slc44a1b

DIOPT Version :10

• Sequence 1: NP_651670.1
• Gene: Ctl2 / 43440
• FlyBaseID: FBgn0039637
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: XP_021336769.1
• Gene: slc44a1b / 503933
• ZFINID: ZDB-GENE-050309-63
• Length: 752
• Species: Danio rerio
• Alignment Length: 813
• Identity: 201/813 - (24%)
• Similarity: 327/813 - (40%)
• Gaps: 229/813 - (28%)

  Fly    28 DRSCTDVPCLLLFVLFLGGWAFIAQYAIRNGDLNKLLVPTDSFNRKCGMD---------SGVLNK 83
            ||||||:|..|||.|||.|...|..:.|..|...:|:...||:...||..         ||:.:.
Zfish    31 DRSCTDLPWFLLFTLFLVGMCGICGFTIATGGAARLVFGYDSYGNTCGQRNEPIEGVRLSGLDHT 95

  Fly    84 KNLFFFDLNQCIDPLVPITGCDTPQVCVETCPRETFVWDTMKDKQSFAELHSRLICLSEEHKAQI 148
            ...|.|.|:.|...::. ....:..:||..||.|..:  |..|.:.||.::...:|..|
Zfish    96 DRKFVFFLDPCNIDIIQ-RKIKSMALCVSQCPTEELL--TYYDLKRFAMMNGSELCSYE------ 151

  Fly   149 RTKSDIQDAINQNQCARWYIKSAPFLKRCLFEFSQGVCDYIPSFLLNGGRSRRELHMLPGNATTE 213
                                                                     |||:....
Zfish   152 ---------------------------------------------------------LPGHKYPS 159

  Fly   214 VQMQADVMYQKMTDAQALVVPQANGKQTPVDEEPIIQCKRRLNEAVIKEKMMQTDTRLAKLVGNM 278
            :..:.| ...|:...::..:|..| :.||||    |.|..:..|||:  ..:..::.|.:|:..:
Zfish   160 LPERFD-KCPKLPVPESKALPVFN-RCTPVD----ISCYAKFAEAVV--TFVSDNSMLNRLIAGV 216

  Fly   279 VAHFYNGTNDAQLLGEKIVEDLVNSWSIVLVACFCTLVASLIYIALMRWLSAPILWFSIFGVLIG 343
            .|                      |..|::..|...||.|:|.:.::|::||.::|.....|::|
Zfish   217 AA----------------------SKEIIVGLCLLALVLSMILMVIIRYISAVLVWILTALVVLG 259

  Fly   344 LLVGIYFSVKQYIHWENTPTVPVHGLNLHSTVKNVLQN---------------QNTWLY---LSI 390
            .|.|.......||.:..|         ::.|:...|..               |...:|   .::
Zfish   260 SLGGTSVLWWLYIDYRMT---------MNETMTKDLTETEEPNGGMKPTKDHAQGLLIYAVSATV 315

  Fly   391 FVGVCFVVILLLVIVLRKRIRIAIALTKEGSK--------AVSSVISTVFFPIFSWILFIAAIAF 447
            |.|    ::|||::.:|||:.:.|||.....|        |:....:.:...:| |:.:|..:
Zfish   316 FTG----ILLLLMLFMRKRVALTIALFHVAGKVFIHLPLLALQPFCTFLALSLF-WVYWIMVL-- 373

  Fly   448 AIGVGLYLGSIGDPSFRMVRQLTKSGEVTTEDCVCEGPAINYTVGGSCKPEVFQQYCSVRLTSFF 512
                 |:||:.|:|.             ..||.    ..:.:.:.|:
Zfish   374 -----LFLGTTGNPE-------------KNEDT----GLVEFRLSGA------------------ 398

  Fly   513 QNRNPCLNTTCSFDSINNPIEIKWAIFYNVFGFLWLSFFISAFSYMVLASTFARWYWTFKKRDVP 577
                                 :::..:|:..|.:|:|.||.|...|.:|.....:|:|..|..:|
Zfish   399 ---------------------LQYMTWYHAVGLIWISEFILACQQMTVAGAVVTYYFTRDKTKLP 442

  Fly   578 YFTLTRAFFQTAVYHLGTVAFGSLILAIVRLIRLVLEYIHEKLKKYDNAVTRAILCCMRCFFWLL 642
            ...:..:..:...|||||||.||.|:.:|::.||:|.|||.:||..:||..|.:|....|..|.|
Zfish   443 VTPILSSVLRLVRYHLGTVAKGSFIITLVKIPRLILMYIHNQLKGKENACARCMLKACICCLWCL 507

  Fly   643 ETFLKFLNRNAYIMCAIHGKNFCSSAADSFNLIMRNFLRVVTLDQVTDFLFFLSKLLL---TAGA 704
            |..|.:||:|||...||:..:||:||.|:|.:::.|.|||.|::.|.||:.||.|:|:   ||.|
Zfish   508 EKCLNYLNQNAYAATAINSTSFCTSARDAFMILVENALRVATINTVGDFVLFLGKVLIVTCTAFA 572

  Fly   705 GASTYYFLDNNPSIIRLNY------IAVPTTVVVIAAFLITSVFFGVYSTAVDTLFLCFLEDCER 763
            |            ::.|||      ..:|..:|.:.|||:...|..::...||.|||||..|.:.
Zfish   573 G------------VLALNYQRDYTEWVLPLIIVCLFAFLVAHCFLSIFEIVVDVLFLCFAIDTKY 625

  Fly   764 NDGSPEKPFFMSKQLMKILGKKNNLPPRQRRGK 796
            |:|:|.:.|:|.|.||:.:.........:.||:
Zfish   626 NNGTPGREFYMDKALMEFVENSRRSMAMEERGR 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl2	NP_651670.1	Choline_transpo	407..762	CDD:461337	106/371 (29%)
slc44a1b	XP_021336769.1	Choline_transpo	311..622	CDD:461337	110/390 (28%)