Protein Alignment Ctl2 and Ctl1

DIOPT Version :10

• Sequence 1: NP_651670.1
• Gene: Ctl2 / 43440
• FlyBaseID: FBgn0039637
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Alignment Length: 796
• Identity: 191/796 - (23%)
• Similarity: 333/796 - (41%)
• Gaps: 197/796 - (24%)

  Fly    25 RQRDRSCTDVPCLLLFVLFLGGWAF---IAQYAIRNGDLNKLLVPTDSFNRKCGMD--------- 77
            |.:.|||||...|.::::|   |.|   ||.::...|:..:::...|||...||:.
  Fly    17 RPKYRSCTDTCWLAIYIIF---WLFLIVIAIFSFVYGNPLRIINGYDSFGNTCGVKYNEKFQGFP 78

  Fly    78 -SGV--LNKKNLFFFDLNQCIDPLVPITGCDTPQVCVETCPRETFVWDTMKDKQSFAELHSRL-- 137
             ||:  |:|..||:||:.:....|         ::||::||.:     ||.......|.:|:.
  Fly    79 LSGMNTLDKPELFYFDVKELKKSL---------KICVKSCPAK-----TMTKGSELLEYYSQTGT 129

  Fly   138 -ICLSEEHKAQIRTKSDIQDAINQNQCARWYIKSAPFLKRCLFEFSQGVCDYIPSFLLNGGRSRR 201
             :|..:.:..|:.|..:  ||           |:..||..|            |||
  Fly   130 QLCKYDYNMQQLTTAGN--DA-----------KTFNFLGPC------------PSF--------- 160

  Fly   202 ELHMLPGNATTEVQMQADVMYQKMTDAQALVVPQANGKQTPVDE-EPII-QCKRRLNEAVIKEKM 264
                                                    ||.| .|:: :|
  Fly   161 ----------------------------------------PVHESSPVLHRC------------- 172

  Fly   265 MQTDTRLAKLVGNMVAHFYNGTNDAQLLGEKIVEDLVNSWSIVLVACFCTLVASLIYIALMRWLS 329
                  :.|..|..|.::|:..|:.. :.::.|.|:.::|.|:.:.|...|:.|:..:.:|.|||
  Fly   173 ------VPKGTGEKVQNYYDMLNNWD-VAQQFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLS 230

  Fly   330 APILWFSIFGVL---IGLLVGIYFSVKQYIHWENTPTVPVHGLNL-HSTVKNVLQNQNTWLYLSI 390
            ..:.|.....|:   :.|.|.::::   |.:..|.     .|:|. :|.::..::||...|.|::
  Fly   231 RIVSWIICVLVIVASVALTVALWYA---YYNIRNK-----SGVNTQYSMLEEFVRNQQAVLTLAV 287

  Fly   391 FVGVCFVVILLLVIVLRKRIRIAIALTKEGSKAVSSVISTVFFPIFSWILFIAAIAFAIGVGLYL 455
            ...:..:::::::..|:.::....||.:|..:.:.::...:..|:.::::.||.::|.:.|.:.|
  Fly   288 LATITMIILIVVIYFLKNKLAGLSALFEEAGQCMMNLPGLLIAPLLAFLVLIAFLSFWVAVIICL 352

  Fly   456 GSIGDPSFRMVRQLTKSGEVTTEDCVCEGP-------AINYTVGGSCKPEVFQQYCSVR-LTSFF 512
            .:...|....:.....|.       ..:.|       ..|.|.....:|....:|.... |.|.|
  Fly   353 ATASSPGQSPIAPFDNSK-------AHQQPLPANALFVSNSTDVNDLRPNARVEYADAGVLRSMF 410

  Fly   513 QNRNPCLNTTCSFDSINNPIEIKWAIFYNVFGFLWLSFFISAFSYMVLASTFARWYWTFKKRDVP 577
                                   |..   |.|.:|...||.|.....||:..|.||:. |....|
  Fly   411 -----------------------WIY---VVGLIWTVEFIFACQQFALAAAVAFWYFQ-KPTSTP 448

  Fly   578 YFTLTRAFFQTAVYHLGTVAFGSLILAIVRLIRLVLEYIHEKLKKYDNAVTRAILCCMRCF---F 639
            .|   .|..:...|||||||.||.::.|.::.||:|.|::.||||.::..:....||::|.   |
  Fly   449 TF---YAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSECAACCLKCCICGF 510

  Fly   640 WLLETFLKFLNRNAYIMCAIHGKNFCSSAADSFNLIMRNFLRVVTLDQVTDFLFFLSKLLLTAGA 704
            ||||.|::|||.|||.:.||...|||.:|..::|.:..|.|:|.|::.|.||:.||.|:::.|.:
  Fly   511 WLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFILFLGKVVVAALS 575

  Fly   705 GASTYYFLDNNPSIIRLNYIAVPTTVVVIAAFLITSVFFGVYSTAVDTLFLCFLEDCERNDGSPE 769
            |......|.:.|.   ||:...|..:::|.:|.|..:...::...|||||||..||...|..|..
  Fly   576 GLIGIVLLKDKPG---LNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCEDKTLNGRSGR 637

  Fly   770 KPFFMSKQLMKILGKK 785
               :....|.|::|::
  Fly   638 ---WAQSNLAKLVGEE 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl2	NP_651670.1	Choline_transpo	407..762	CDD:461337	104/365 (28%)
Ctl1	NP_647884.1	Choline_transpo	287..629	CDD:461337	104/381 (27%)