Protein Alignment Ctl2 and slc44a2

DIOPT Version :10

• Sequence 1: NP_651670.1
• Gene: Ctl2 / 43440
• FlyBaseID: FBgn0039637
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: XP_005165806.2
• Gene: slc44a2 / 324345
• ZFINID: ZDB-GENE-030131-3065
• Length: 847
• Species: Danio rerio
• Alignment Length: 799
• Identity: 281/799 - (35%)
• Similarity: 404/799 - (50%)
• Gaps: 123/799 - (15%)

  Fly     9 NKYGEPLRYDRNFTGPRQRDRSCTDVPCLLLFVLFLGGWAFIAQYAIRNGDLNKLLVPTDSFNRK 73
            :|||||.::|..|.||.. :|.|||:.|.:||:|.|.|:..:...|...||..|::.||||..:.
Zfish    10 SKYGEPRKFDPTFKGPIY-NRGCTDILCCILFILALLGYFAVGILAWSQGDPRKVIYPTDSTGQF 73

  Fly    74 CGMDSGVLNKKN-LFFFDLNQCIDPLVPIT-GCDTPQVCVETCPRE--TFV--WDTMKDKQSFAE 132
            ||.....|.||. ||:|::.:|..|||.:. .|.|.|:|||.||.:  |.|  ..:..||..:.:
Zfish    74 CGQAGTPLEKKPLLFYFNIMKCASPLVLLEFQCPTTQICVEKCPDKFMTLVNALKSQSDKTYYTQ 138

  Fly   133 LHSRLICLSEEHKAQIRTKSDIQDAINQNQCARWYIKSAPFLKRCLFEFSQGVCDYIPSF-LLNG 196
                 .|     |..:....:....:::..|......|..|.:|||           |:. .:.|
Zfish   139 -----FC-----KEGVDMTKNAPQILSEGLCPSILFPSKNFTRRCL-----------PALETMKG 182

  Fly   197 GRSRRELHMLPGNATTEVQMQADVMYQKMTDAQALVVPQANGKQTPVDEEPIIQCKRRLNEAVIK 261
            |                                  ||...|..|..||:..:|.....||.|
Zfish   183 G----------------------------------VVVIGNETQFTVDQGEVINATDLLNAA--- 210

  Fly   262 EKMMQTDTRLAKLVGNMVAHFYNGTNDAQLLGEKIVEDLVNSWSIVLVACFCTLVASLIYIALMR 326
            :|            .|:|.       :|:.:..:|.||...||..:|:.....::.|||:|.|:|
Zfish   211 KK------------SNVVV-------EARAVAMRIFEDYTQSWHWILLGLVIAMLISLIFILLLR 256

  Fly   327 WLSAPILWFSIFGVLIGLLVGIYFSVKQY--IHWENTPTVPVHGLNLHSTVKNVLQNQNTWLYLS 389
            :|:..::|..|..|:|.:..||:....||  :..:....|.:..|.|.:.....||.|.|||...
Zfish   257 FLAGVMVWVMIIMVIIVIGYGIFHCYMQYASLKGQAGSDVTIKDLGLQTDFSVYLQIQQTWLAFM 321

  Fly   390 IFVGVCFVVILLLVIVLRKRIRIAIALTKEGSKAVSSVISTVFFPIFSWILFIAAIAFAIGVGLY 454
            |.:.:...|||||:|.||||:.|||||.||.|||:..|:|::|:|:.::.|....||:.....::
Zfish   322 IILCIVEAVILLLLIFLRKRLLIAIALIKEASKAIGHVMSSLFYPLLTYALMSLVIAYWAITAVF 386

  Fly   455 LGSIGDPSFRMVRQLTKSGEVTTEDCVCEGPAINYTVGGSCKPEVFQQYCSVRLTSFFQNRNPCL 519
            |.:..:|.:::         ..|.:|       :|: ..:|.|..|.   :..:|:      .|.
Zfish   387 LSTSNEPIYKV---------FNTSNC-------SYS-RATCNPATFN---TSNVTT------ECP 425

  Fly   520 NTTCSFDSI-NNPIEIKWAI---FYNVFGFLWLSFFISAFSYMVLASTFARWYWTFKK-RDVPYF 579
            :..|.|... ...:..||.|   |||:|.|.|...|:.|...:.||..||.:||.||| .|:|.|
Zfish   426 DAECLFAFYGGETLYHKWLIVFQFYNLFLFFWCVNFVIALGQVTLAGAFASYYWAFKKPDDMPAF 490

  Fly   580 TLTRAFFQTAVYHLGTVAFGSLILAIVRLIRLVLEYIHEKLKKYDNAVTRAILCCMRCFFWLLET 644
            .:..:..:...||.||:||||||||||::||:||||:.:|||...|...:.:|.|::|.||.||.
Zfish   491 PIFNSLGRALRYHTGTLAFGSLILAIVQVIRVVLEYLDQKLKGAQNKFAKFLLSCLKCCFWCLEK 555

  Fly   645 FLKFLNRNAYIMCAIHGKNFCSSAADSFNLIMRNFLRVVTLDQVTDFLFFLSKLLLTAGAGASTY 709
            |:||:|||||||.||:|||||:||.|:|.|:|||.:||..||:|||||.||.|||:....|..::
Zfish   556 FIKFINRNAYIMVAIYGKNFCTSARDAFFLLMRNIVRVAVLDKVTDFLLFLGKLLIVGIVGICSF 620

  Fly   710 YFLDNNPSIIR-----LNYIAVPTTVVVIAAFLITSVFFGVYSTAVDTLFLCFLEDCERNDGSPE 769
            :|......|.:     |||..||...||..|:||...||.||:..||||||||.||.||||||.:
Zfish   621 FFFTGKIKIAQDVTPALNYYWVPILTVVFGAYLIAHGFFSVYAMCVDTLFLCFCEDLERNDGSSD 685

  Fly   770 KPFFMSKQLMKILGKKNNL 788
            ||||||.:|.:||..:.::
Zfish   686 KPFFMSPELHQILSIEKSI 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl2	NP_651670.1	Choline_transpo	407..762	CDD:461337	152/364 (42%)
slc44a2	XP_005165806.2	Choline_transpo	322..678	CDD:461337	160/381 (42%)
		PTZ00341	<636..>814	CDD:173534	39/69 (57%)