Protein Alignment Ctl2 and Slc44a5

DIOPT Version :10

• Sequence 1: NP_651670.1
• Gene: Ctl2 / 43440
• FlyBaseID: FBgn0039637
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: XP_006501551.1
• Gene: Slc44a5 / 242259
• MGIID: 3035141
• Length: 720
• Species: Mus musculus
• Alignment Length: 815
• Identity: 260/815 - (31%)
• Similarity: 394/815 - (48%)
• Gaps: 131/815 - (16%)

  Fly     1 MTESVELMNKYGEPLRYDRNFTGPRQRDRSCTDVPCLLLFVLFLGGWAFIAQYAIRNGDLNKLLV 65
            :|||.:  ...|:|.|||.:|.||..: |:||||.|.|:|:||:.|:..:...|..:||..|:..
Mouse    13 ITESED--QDVGDPRRYDPDFQGPTAK-RTCTDVLCCLIFLLFILGYVLLGLLAWAHGDPRKMAY 74

  Fly    66 PTDSFNRKCGMDSGV--LNKKNLFFFDLNQCIDPLVPI-TGCDTPQVCVETCPRETFVWDTM--- 124
            ||||....|| ..|.  .||..||:|::.:|..|.:.: ..|.|.|:||..||.....:..|
Mouse    75 PTDSQGHFCG-QKGTPNENKTVLFYFNIFRCTSPSMMLRLQCSTTQICVSRCPERFLTYLDMQFL 138

  Fly   125 -KDKQSFAELHSRLICLSEEHKAQIRTKSDIQDAINQNQCARWYIKSAPFLKRCLFEFSQGVCDY 188
             |:.:::.|.: |..|     ||:.:....::|.:....|......|.|||:||:.:.|
Mouse   139 NKEDKNYWEYY-RQFC-----KAKAKPVETLRDLLISGDCPLAVYPSRPFLQRCIPDLS------ 191

  Fly   189 IPSFLLNGGRSRRELHMLPGNATTEVQMQADVMYQKMTDAQALVVPQANGKQTPVDEEPIIQCKR 253
                .|||       ...||:.            .|..|...
Mouse   192 ----ALNG-------TWTPGSR------------MKFEDGSG----------------------- 210

  Fly   254 RLNEAVIKEKMMQTDTRLAKLVGNMVAHFYNGTND---AQLLGEKIVEDLVNSWSIVLVACFCTL 315
                        ||.|.|.      .....||.:|   |:.:|.|::||...||..:|:.....:
Mouse   211 ------------QTRTMLE------FREAANGISDLINARTIGLKLLEDYATSWKWILIGLTVAM 257

  Fly   316 VASLIYIALMRWLSAPILWFSIFGVLIGLLVGIYFSVKQYIHWENTP--TVPVHGLNLHSTVKNV 378
            ..|..::.|:|:.:..:.||.|||||..:..||::...:|...:..|  |..::|..:...|...
Mouse   258 ALSWTFLILLRFTAGFLFWFFIFGVLGIIGYGIWYCFLEYSSIQQRPQSTFWMYGFGIQRRVNMF 322

  Fly   379 LQNQNTWLYLSIFVGVCFVVILLLVIVLRKRIRIAIALTKEGSKAVSSVISTVFFPIFSWILFIA 443
            ...:.||..:.|.:....::|::::|.||.||::||.|.:|||||:|.:.|.:.:|:.::||...
Mouse   323 FHLKETWFSMMIILSAIEIIIIIVLIFLRTRIQVAIILLQEGSKAISYLPSALIYPVLTFILLSI 387

  Fly   444 AIAFAIGVGLYLGSIGDPSFRMVRQLTKSGEVTTEDCVCEGPAINYT------VGGSCKPEVFQQ 502
            .|::.....::|.:.|.|.|::   :..:|:...||..|:.....||      .|.||.
Mouse   388 CISYWAVTAVFLATSGVPIFKV---MVPAGQCIYEDETCDPEIFPYTNIPKDCPGASCN------ 443

  Fly   503 YCSVRLTSFFQNRNPCLNTTCSFDSINNPIEIKWAIFYNVFGFLWLSFFISAFSYMVLASTFARW 567
                  .:|:..|:...|...:|.            .||:|.||||..|:.|.....||..||.:
Mouse   444 ------FAFYGGRSMYHNYILTFQ------------VYNLFAFLWLINFVIALGQCALAGAFASY 490

  Fly   568 YWTFKK-RDVPYFTLTRAFFQTAVYHLGTVAFGSLILAIVRLIRLVLEYIHEKLKKYDNAVTRAI 631
            ||..|| .|:|.:.|..||.:...||.|::||||||||.|::.::::||:..:|||..|:..:.:
Mouse   491 YWAMKKPDDIPPYPLFTAFGRAVRYHTGSLAFGSLILASVQMFKVIVEYLDRRLKKAQNSAAQFL 555

  Fly   632 LCCMRCFFWLLETFLKFLNRNAYIMCAIHGKNFCSSAADSFNLIMRNFLRVVTLDQVTDFLFFLS 696
            .||::|.||.||..:||||||||||.|::|||||.|..|:|.|:|||.|:|...|:||.|:..|.
Mouse   556 HCCLQCCFWCLEKMVKFLNRNAYIMIALYGKNFCESTRDAFYLLMRNILKVTVTDEVTYFVLLLG 620

  Fly   697 KLLLTAGAGASTYYFLDNNPSII-----RLNYIAVPTTVVVIAAFLITSVFFGVYSTAVDTLFLC 756
            |:|::...|...:........||     .|||..||...:|..:::|...||.|||..|:|:|:|
Mouse   621 KVLVSGIVGVLAFLLFTERLQIIVDGPTTLNYYWVPFLTLVFGSYMIAHGFFSVYSMCVETIFIC 685

  Fly   757 FLEDCERNDGSPEKPFFMSKQLMKILGKKNNLPPR 791
            |.||.||||||.|||:|::..|..||.||...|.|
Mouse   686 FCEDLERNDGSAEKPYFVTPSLHSILTKKRPGPQR 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl2	NP_651670.1	Choline_transpo	407..762	CDD:461337	135/366 (37%)
Slc44a5	XP_006501551.1	Choline_transpo	351..691	CDD:461337	135/366 (37%)