Protein Alignment Ctl2 and Ctl1

DIOPT Version :10

• Sequence 1: NP_651670.1
• Gene: Ctl2 / 43440
• FlyBaseID: FBgn0039637
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: XP_316311.5
• Gene: Ctl1 / 1276904
• VectorBaseID: AGAMI1_007636
• Length: 690
• Species: Anopheles gambiae
• Alignment Length: 788
• Identity: 192/788 - (24%)
• Similarity: 334/788 - (42%)
• Gaps: 185/788 - (23%)

  Fly    29 RSCTDVPCLLLFVLFLGGWAFIAQYAIRNGDLNKLLVPTDSFNRKCGMDS------------GVL 81
            ||.||:..|:|:|:|......||.::...|:..:::...|||...||:.|            ...
Mosquito    18 RSPTDIFWLVLYVVFWIALIVIAVFSFIYGNPLRIINGYDSFGNTCGVRSNDKFSNFPLSGMNTE 82

  Fly    82 NKKNLFFFDLNQCIDPLVPITGCDTPQVCVETCPRETFVWDTMKDKQSFAELH------SRLICL 140
            :|..|||.|:.:....|         ::||:.||:        ::..:.|||:      ...:|.
Mosquito    83 DKPYLFFLDIKELRHTL---------KICVKECPQ--------RELLNAAELYRYYEDRKTKLCR 130

  Fly   141 SEEHKAQIRTKSDIQDAINQNQCARWYIKSAPFLKRCLFEFSQGVCDYIPSFLLNGGRSRRELH- 204
            .:.:.:.::|    |:|   ||.|::            |:|: |.|...|.:     :|...||
Mosquito   131 YDFNMSMLQT----QEA---NQGAKY------------FDFN-GPCPPFPVY-----QSAPVLHR 170

  Fly   205 MLPGNATTEVQMQADVMYQKMTDAQALVVPQANGKQTPVDEEPIIQCKRRLNEAVIKEKMMQTDT 269
            .:|......:| |...||..:...:|.
Mosquito   171 CIPTGVNAPLQ-QVKKMYALINSWEAT-------------------------------------- 196

  Fly   270 RLAKLVGNMVAHFYNGTNDAQLLGEKIVEDLVNSWSIVLVACFCTLVASLIYIALMRWLSAPILW 334
                                    :::..||..:|..:::.|..:||.|::.|||:.||:..:.|
Mosquito   197 ------------------------QQVFSDLYKAWPTIVLICALSLVFSIVMIALLHWLATIVSW 237

  Fly   335 FSIFGVLI------GLLVGIYFSVKQYIHWENTPTVPVHGLNLH---STVKNVLQNQNTWLYLSI 390
            .....|::      |:|...|:..|             |.|:..   |.::.:::|:.| :|:..
Mosquito   238 LICIIVVVASVGITGVLWWSYYKAK-------------HTLDTDQQLSYLEELVRNEAT-IYVLA 288

  Fly   391 FVGVCFVVILLLVI-VLRKRIRIAIALTKEGSKAVSSVISTVFFPIFSWILFIAAIAFAIGVGLY 454
            ....|.::|||:|| .||:::....||.:|..|.:..:......|:.:::.....:||.:.|.:.
Mosquito   289 IAATCIMIILLVVIYYLREKLTGLAALFEEAGKCMLQLPGLAGPPLLAFLALSIFLAFWVVVVVC 353

  Fly   455 LGSIGDPSFRMVRQLTKSGEVTTEDCVCEGPAINYTVGGSCKPEVFQQYCSVRLTSFFQNRNPCL 519
            |.:...|.   |:.|....::.....:...|.:        |||:    .....|||...:
Mosquito   354 LATANYPG---VKPLLPLAQLEDSASIANDPKL--------KPEL----AGKNDTSFKSFK---- 399

  Fly   520 NTTCSFDSINNPIEIKWAIFYNVFGFLWLSFFISAFSYMVLASTFARWYWTFKKRDVPYFTLTRA 584
              ...:..:|   .::..::..:.|.:|.|.||.|...:.:|...|.||:. |..|.|   :..|
Mosquito   400 --LVEYHDVN---VLRHMLWIYIIGLIWTSEFIFACQQLAIAGAVAFWYFR-KPTDSP---VLLA 455

  Fly   585 FFQTAVYHLGTVAFGSLILAIVRLIRLVLEYIHEKLKKYDNAVTRAILCCMR---CFFWLLETFL 646
            ..:...||||:||.||||:.|.::.||:|.|::.|||::....:....||:|   |.|||||.|:
Mosquito   456 IAKLVKYHLGSVAKGSLIITIFKIPRLILTYLYAKLKRHQQEGSECASCCLRCCICSFWLLEKFI 520

  Fly   647 KFLNRNAYIMCAIHGKNFCSSAADSFNLIMRNFLRVVTLDQVTDFLFFLSKLLLTAGAGASTYYF 711
            ::||.|||.:.||.|.|||.:|..::|.::.|.|:|.|::.:.||:.||.||.:.:..|..:...
Mosquito   521 RYLNHNAYTVIAIEGVNFCPAAKIAWNALVTNALQVATINGIGDFVLFLGKLAVASICGLISILL 585

  Fly   712 LDNNPSIIRLNYIAVPTTVVVIAAFLITSVFFGVYSTAVDTLFLCFLEDCERNDGSPEKPFFMSK 776
            |.:||.   |::...|..::.:.||.|..:...:|...|||||||..||...|..|..   :...
Mosquito   586 LRDNPD---LHFYMAPVIIITVFAFFIAHIILSLYEMVVDTLFLCVCEDRTINGNSGR---WKES 644

  Fly   777 QLMKILGK 784
            .|.::||:
Mosquito   645 NLARLLGE 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl2	NP_651670.1	Choline_transpo	407..762	CDD:461337	105/357 (29%)
Ctl1	XP_316311.5	None