Protein Alignment Ctl2 and Slc44a1

DIOPT Version :10

• Sequence 1: NP_651670.1
• Gene: Ctl2 / 43440
• FlyBaseID: FBgn0039637
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: XP_006537594.1
• Gene: Slc44a1 / 100434
• MGIID: 2140592
• Length: 718
• Species: Mus musculus
• Alignment Length: 796
• Identity: 213/796 - (26%)
• Similarity: 338/796 - (42%)
• Gaps: 207/796 - (26%)

  Fly    28 DRSCTDVPCLLLFVLFLGGWAFIAQYAIRNGDLNKLLVPTDSFNRKCGM---------DSGV--L 81
            ||||||:|.|||||||..|..||..:::..|...:|:...||:...||.         :||:  .
Mouse    22 DRSCTDIPWLLLFVLFCIGMGFICGFSVATGAAARLVSGYDSYGNICGQRNAKLEAIPNSGLDHT 86

  Fly    82 NKKNLFFFD------LNQCIDPLVPITGCDTPQVCVETCPRETFVWDTMKDKQSFAELHSRLICL 140
            ::|.:||.|      :|:.|..:.         :||..|||:..  .|:.|.|.|||::...:|
Mouse    87 HRKYVFFLDPCNLDLINRKIKSIA---------LCVAACPRQEL--KTLSDVQKFAEINGSALC- 139

  Fly   141 SEEHKAQIRTKSDIQDAINQNQCARWYIKSAPFLKRCLFEFSQGVCDYIPSFLLNGGRSRRELHM 205
                                    .:.||.:.:   .|...|.|.|..:|
Mouse   140 ------------------------SYNIKPSEY---TLTSKSSGFCPKLP--------------- 162

  Fly   206 LPGNATTEVQMQADVMYQKMTDAQALVVPQANGKQTPVDEEPIIQCKRRLNEAVIKEKMMQTDTR 270
            :|.:|.                     :|..: :..||:    |.|..:..||:|
Mouse   163 VPASAP---------------------IPFFH-RCAPVN----ISCYAKFAEALI---------- 191

  Fly   271 LAKLVGNMVAHFYNGTNDAQLLGEKIVEDLVNSWSIVLVACFCTLVASLIYIALMRWLSAPILWF 335
             ..:..|.|.|             :::..::.|..|:|..|..:||.|:|.:.::|::|..::|.
Mouse   192 -TFVSDNSVLH-------------RLISGVMTSKEIILGLCLLSLVLSMILMVIIRYISRVLVWI 242

  Fly   336 SIFGVLIGLLVGIYFSVKQYIHWENTPTVPVHGLNLHSTVKNVLQ----NQNTWLYLSIFVGVCF 396
            ....|::|.|.|.......|.....:|.        .:.:...||    |....|..:|...|..
Mouse   243 LTVLVILGSLGGTGVLWWLYAKQRRSPK--------EAVIPEQLQIAEDNLRALLIYAISATVFT 299

  Fly   397 VVILLLVIVLRKRIRIAIALTKEGSKAVSSVISTVFFPIFSWILFIAAIAFAIGVGLYLGSIGDP 461
            |::.|:::|:|||:.:.|||.....|....:...||.|.:::...:...|:.|...|:||:.|.
Mouse   300 VILFLIMLVMRKRVALTIALFHVAGKVFIHLPLLVFQPFWTFFALVLFWAYWIMTLLFLGTTGS- 363

  Fly   462 SFRMVRQLTKSGEVTTEDCVCEGPAINYTVGGSCKPEVFQQYCSVRLTSFFQNRNPCLNTTCSFD 526
                                    |:....|       |.:|
Mouse   364 ------------------------AVQNEQG-------FVEY----------------------- 374

  Fly   527 SINNPIEIKWAIFYNVFGFLWLSFFISAFSYMVLASTFARWYWTFKKRDVPYFTLTRAFFQTAVY 591
            .|:.|::..|  :|:|.|.:|:|.||.|...|.:|.....:|:|..||::|:..:..:..:...|
Mouse   375 KISGPLQYMW--WYHVVGLIWISEFILACQQMTVAGAVVTYYFTRDKRNLPFTPILASVNRLIRY 437

  Fly   592 HLGTVAFGSLILAIVRLIRLVLEYIHEKLKKYDNAVTRAILCCMRCFFWLLETFLKFLNRNAYIM 656
            ||||||.||.|:.:|::.|:||.|||.:||..:||..|.:|....|..|.||..|.:||:|||..
Mouse   438 HLGTVAKGSFIITLVKIPRMVLMYIHSQLKGKENACARCMLKSCICCLWCLEKCLSYLNQNAYTA 502

  Fly   657 CAIHGKNFCSSAADSFNLIMRNFLRVVTLDQVTDFLFFLSKLLLTAGAGASTYYFLDNNPSIIRL 721
            .||:..|||:||.|:|.:::.|.|||..::.|.||:.||.|:|:....|.:         .|:.|
Mouse   503 TAINSTNFCTSAKDAFVILVENALRVAAINTVGDFMLFLGKVLIVCSTGLA---------GIMLL 558

  Fly   722 NY------IAVPTTVVVIAAFLITSVFFGVYSTAVDTLFLCFLEDCERNDGSPEKPFFMSKQLMK 780
            ||      ..:|..:|.:.|||:...|..:|...||.|||||..|.:.|||||.:.|:|.|.||:
Mouse   559 NYQQDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGREFYMDKVLME 623

  Fly   781 ILGKKNNLPPRQRRGK 796
            .:  :|:....:..||
Mouse   624 FV--ENSRKAMKEAGK 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl2	NP_651670.1	Choline_transpo	407..762	CDD:461337	111/360 (31%)
Slc44a1	XP_006537594.1	Choline_transpo	293..603	CDD:461337	115/375 (31%)