Protein Alignment Ctl2 and slc44a2

DIOPT Version :10

• Sequence 1: NP_651670.1
• Gene: Ctl2 / 43440
• FlyBaseID: FBgn0039637
• Length: 796
• Species: Drosophila melanogaster
• Sequence 2: XP_031755250.1
• Gene: slc44a2 / 100379903
• XenbaseID: XB-GENE-957797
• Length: 715
• Species: Xenopus tropicalis
• Alignment Length: 795
• Identity: 272/795 - (34%)
• Similarity: 410/795 - (51%)
• Gaps: 122/795 - (15%)

  Fly    11 YGEPLRYDRNFTGPRQRDRSCTDVPCLLLFVLFLGGWAFIAQYAIRNGDLNKLLVPTDSFNRKCG 75
            ||||.:||.||.|| ..:|.|||:.|.:|.||.:..:..:...|...||..|::.||||..:.||
 Frog    13 YGEPKKYDPNFKGP-IHNRGCTDILCCILIVLGIIAYVAVGIVAWTYGDPRKVIYPTDSKGQFCG 76

  Fly    76 MDSGVLNKKN--LFFFDLNQCIDPLVPIT-GCDTPQVCVETCPRETFVW-DTMKDKQSFAELHSR 136
             .:|..|:|.  ||:|::.:|..|||.:. .|.|||:|||.||.:...: ..:..:|:|.  :.:
 Frog    77 -QAGTPNEKKPFLFYFNIMKCASPLVLLQFQCPTPQICVEKCPDKFLTYLSVVTTQQNFD--YYK 138

  Fly   137 LICLSEEHKAQIRTKSDIQDAINQNQCARWYIKSAPFLKRCLFEFS--QGVCDYIPSFLLNGGRS 199
            ..|   ::.....:||.: :.:....|......|.||.:||....|  :||
 Frog   139 QFC---QYGFNNFSKSPV-EVLRDRDCPAMITPSKPFTRRCFPAISTQKGV-------------- 185

  Fly   200 RRELHMLPGNATTEVQMQADVMYQKMTDAQALVVPQANGKQTPVDEEPIIQCKRRLNEAVIKEKM 264
                 ::.||:||......|                   ||..|.:  :::..::.|..:
 Frog   186 -----VMVGNSTTFDDGTGD-------------------KQRNVTD--LVEGAKKANVVL----- 219

  Fly   265 MQTDTRLAKLVGNMVAHFYNGTNDAQLLGEKIVEDLVNSWSIVLVACFCTLVASLIYIALMRWLS 329
                                   :|:.:..||.||...||..:::.....:|.|||::.|:|:|:
 Frog   220 -----------------------EARQVAMKIFEDYTVSWYWIIIGLLIAMVISLIFVVLLRFLA 261

  Fly   330 APILWFSIFGVLIGLLVGIYFSVKQY--IHWENTPTVPVHGLNLHSTVKNVLQNQNTWLYLSIFV 392
            ..::|..|..|:..:..||:....:|  :..|....|.:..:...:.::..|..:.|||...|.:
 Frog   262 GIMVWVMIVLVIAVMGYGIFHCYMEYARLKGEAGSDVTLKDIGFQTDIRVYLHLRQTWLAFMIIL 326

  Fly   393 GVCFVVILLLVIVLRKRIRIAIALTKEGSKAVSSVISTVFFPIFSWILFIAAIAFAIGVGLYLGS 457
            .:..|:::||:|.|||||.|||||.||.|:||.||:|::.||:|:::|....||:.....::|.:
 Frog   327 CILEVIVILLLIFLRKRILIAIALIKEASRAVGSVMSSLVFPLFTFLLVCLCIAYWAITAVFLST 391

  Fly   458 IGDPSFRMVRQLTKSGEVTTEDCVCEGPAINYTVGGSCKPEVFQQYCSVRLTSFFQNRNPCLNTT 522
            ..:..:::..:..           |:      ..|.:|.||.|......||         |.:.|
 Frog   392 SNEAVYKVFNETQ-----------CD------FSGKTCDPETFNTTNVTRL---------CPDAT 430

  Fly   523 CSF-----DSINNPIEIKWAIFYNVFGFLWLSFFISAFSYMVLASTFARWYWTFKK-RDVPYFTL 581
            |.|     ::..:...|.:.| ||.|.||||:.|:.|...:.||..||.:||.||| .|:|.|.:
 Frog   431 CQFAFYGGETYYHKYLIVFQI-YNAFMFLWLANFVIALGQVTLAGAFASYYWAFKKPDDMPAFPI 494

  Fly   582 TRAFFQTAVYHLGTVAFGSLILAIVRLIRLVLEYIHEKLKKYDNAVTRAILCCMRCFFWLLETFL 646
            ..:..:...||.|::||||||||||:|||::|||:..|||..||...|.:|||::|.||.||.|:
 Frog   495 FSSLGRALRYHTGSLAFGSLILAIVQLIRILLEYLDHKLKGADNKCARFLLCCLKCCFWCLEKFI 559

  Fly   647 KFLNRNAYIMCAIHGKNFCSSAADSFNLIMRNFLRVVTLDQVTDFLFFLSKLLLTAGAGASTYYF 711
            ||||||||||.||:|.|||:||.::|.|:|||.:||..||:|||||.||.|||:....|...::|
 Frog   560 KFLNRNAYIMIAIYGTNFCTSARNAFFLLMRNIVRVAVLDKVTDFLLFLGKLLVVGCVGILAFFF 624

  Fly   712 LDNNPSIIR-----LNYIAVPTTVVVIAAFLITSVFFGVYSTAVDTLFLCFLEDCERNDGSPEKP 771
            ......|::     |||..||...|::.::||...||.||...||||||||.||.||||||.|:|
 Frog   625 FSRRIQIVQDTAPTLNYYWVPILTVILGSYLIAHGFFSVYGMCVDTLFLCFCEDLERNDGSLERP 689

  Fly   772 FFMSKQLMKILGKKN 786
            ::||.:|.:||.||:
 Frog   690 YYMSPELSQILLKKD 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl2	NP_651670.1	Choline_transpo	407..762	CDD:461337	155/365 (42%)
slc44a2	XP_031755250.1	Choline_transpo	324..680	CDD:461337	161/382 (42%)