Protein Alignment yem and HPC2

DIOPT Version :10

• Sequence 1: NP_001263054.1
• Gene: yem / 43439
• FlyBaseID: FBgn0005596
• Length: 1101
• Species: Drosophila melanogaster
• Sequence 2: NP_009774.4
• Gene: HPC2 / 852516
• SGDID: S000000419
• Length: 625
• Species: Saccharomyces cerevisiae
• Alignment Length: 738
• Identity: 143/738 - (19%)
• Similarity: 257/738 - (34%)
• Gaps: 202/738 - (27%)

  Fly   202 RKRMVSSSSESSS---SSSGDDDENDDGNNE---------EDDESDSED--DSEENDESDSEDDS 252
            :|.:|..:|:|.|   .|||......|.|.|         ::..|||||  :...|.:::.:..:
Yeast     3 QKAIVLDNSKSGSKQTKSSGKMQTQTDTNAEVLNTDNSIKKETGSDSEDLFNKFSNKKTNRKIPN 67

  Fly   253 ESESLEDEDSAATAKSSSKYKDNHQAKRAKVIVTGKSKPS----SSSLTSGKKPPTKPI---TTS 310
            .:|.|        ||:.:..|.   |..:.:|::|.|..|    |||.|:....||...   |..
Yeast    68 IAEEL--------AKNRNYVKG---ASPSPIIISGSSSTSPSGPSSSSTNPMGIPTNRFNKNTVE 121

  Fly   311 SSSNSPRP-STVEISDTEDGQDPIQTQPSSQLQSLPQSQAQAQALKKVVKTTTVKDMLKAKRDSF 374
            ...:||.| .|...:|||:.:   |...:...::.|:..:.:.|.|
Yeast   122 LYQHSPSPVMTTNKTDTEEKR---QNNRNMDNKNTPERGSSSFAAK------------------- 164

  Fly   375 LKSQSGTAAVKGVGNGELKCVSTDVSSSDSSDMESEHGRADRQAGQHGKDGQENLRTADTLLPTT 439
                            :|| :|:.::.|.:.|.::.|        .:..:|.:|...|...:|:.
Yeast   165 ----------------QLK-ISSLLTISSNEDSKTLH--------INDTNGNKNSNAASNNIPSA 204

  Fly   440 LDADIVTAVNSFKEAVKSRDMCGKKFNLDVKLSPLLLRVYEAVLCTDRNERNMVFSHIEYQLQLP 504
            . |::.|..||.:..:|.......|     .|:|       .|:...:|....:..........|
Yeast   205 Y-AELHTEGNSIESLIKPPSSPRNK-----SLTP-------KVILPTQNMDGTIAKDPHLGDNTP 256

  Fly   505 KYYMLRKGKQVRAKEEKRKSTI-MLEKLRRAVAVVMPKAVANYETELRTFAEQAAADVNSELPPK 568
            ...:.:....|....|....:: ...|...::...:.||.|...:..|:.:....:|.|.....|
Yeast   257 GILIAKTSSPVNLDVESTAQSLGKFNKSTNSLKAALTKAPAEKVSLKRSISSVTNSDSNISSSKK 321

  Fly   569 MPRKKFQWTSELRHLLYDVYQARWTSYAFLAK---RKESLEEFINWYLKEKVVELWPPGWMRLDE 630
            ...:|.:.:|              ::.|.|.|   .|.|.:...|
Yeast   322 PTSEKAKKSS--------------SASAILPKPTTTKTSKKAASN-------------------- 352

  Fly   631 LQREITRYKNAKLKAKEKPKAPPASASPKPVGVVSAPEQMPPASSYLKAVEDPRSRGNSDTDSAT 695
             ..:.||.|||..|.....|....:.|.     ::..::...:.|.:||.|..:.:|.:.|::..
Yeast   353 -SSDSTRKKNASNKTTSAIKKESNAGSK-----LNTVKKENSSLSSIKATEKEKDKGGNSTEAKN 411

  Fly   696 SASSNSLKRKLKEMPKQTSKPPKKKVAKQVPLQPQLTPHPQFQLAPAATAA------VSIPAISN 754
            |.|:      :::.|  |:|.||:.||     .|.::| |:. |..|.|.|      :.:|....
Yeast   412 STSN------VRKEP--TAKSPKRLVA-----APTVSP-PKI-LQTAETKAKEPSILIDVPLYQA 461

  Fly   755 NNNHLPHLDTLLSMPSTSAQAAALNAAAVAAASTVL-DLASPSRKIDLNTSNNFYNLITAASLAA 818
            :.|  .:||.              |...:...||:: :...|..|......::..||:...|..:
Yeast   462 DTN--DYLDE--------------NGQVIFNLSTLIKEKYHPKSKELAQLKDSKRNLLMQLSDHS 510

  Fly   819 SGN---PSPHSGDGQAKVIVGARPSPHVINLDDYQCTSDILQTSKQLAATTTVITAISKAAQTTS 880
            :|:   .....||              ||.|||   ..|:.:...::...|..:|       ||.
Yeast   511 NGSLEKEKDEEGD--------------VIELDD---DEDMEEDEGEIDTETNTVT-------TTI 551

  Fly   881 VARESSSESDGVEIVGVFPASKP 903
            ..::.|....|..::|.:....|
Yeast   552 SPKKKSHPMKGKNLIGKYDVEDP 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yem	NP_001263054.1	HUN	127..178	CDD:462581
		UBN_AB	436..633	CDD:464081	30/200 (15%)
HPC2	NP_009774.4	HUN	<569..601	CDD:462581	1/6 (17%)