Protein Alignment yem and ubn2a

DIOPT Version :9

• Sequence 1: NP_001263054.1
• Gene: yem / 43439
• FlyBaseID: FBgn0005596
• Length: 1101
• Species: Drosophila melanogaster
• Sequence 2: XP_005165772.1
• Gene: ubn2a / 555525
• ZFINID: ZDB-GENE-070112-612
• Length: 1176
• Species: Danio rerio
• Alignment Length: 1234
• Identity: 286/1234 - (23%)
• Similarity: 463/1234 - (37%)
• Gaps: 300/1234 - (24%)

  Fly     4 GGEHKRVTLTSIIQGDAGFSRFGSNILEPDAASAAPD--------NSSKPTTKTAKCIRIKLDLF 60
            |.:::|..|......:..|.|.|...:.....:.|.|        :|.:|..||   :|:.|.|.
Zfish    20 GADNRRRRLEEDGAAEMSFDREGRMKMMGTGVTTAGDRGGLIGKRDSEEPKGKT---VRLNLCLS 81

  Fly    61 ETDSNKYPEFNYSRLLYLEKKKTKKLKQVSTTNGSAS-TDPFADNDDD-----VARIVKELEAKY 119
            |.......|||||.|:..::.|    |....:..|.. .|||  |||:     |..:.|:.|:||
Zfish    82 EPSEQCSAEFNYSELIQSQQPK----KNPPCSKSSLDPNDPF--NDDEKERLQVEALAKKFESKY 140

  Fly   120 GNSYATGRGKSKKDDYRDIGMGYDESDSFIDNTEAYDEIIPEEAETLEGGFYINCGALEFKNLTK 184
            ||: ...|.|.:..|..|||.||||||.||||:|||||::|....|..||||||.|.|:|:
Zfish   141 GNA-GKKRRKDRMQDLIDIGFGYDESDPFIDNSEAYDELVPASLTTKLGGFYINTGTLQFR---- 200

  Fly   185 KSYTTRTDAIIKMPERSRKRMVSSSSESSSSSSGDDDENDDGNNEEDDESDSEDDSEENDESDSE 249
                                       ::|.|.|:|...|:.....|.|.......::.|....|
Zfish   201 ---------------------------AASESEGEDKVKDEKPRIRDGEEPLMKRRKKKDVIGIE 238

  Fly   250 DDSESESLEDEDSAA--------TAKSSSKYKDN-------HQAKRAKVIVTGKSKPSSSSLTSG 299
            :....::...:...|        ..|.....||:       .:..|.|..:. |...|||.|...
Zfish   239 EKKPRKNKVAKQGVAGLSLHRPEKKKRKKLMKDSLCLAAMLRRFTREKEEIR-KQDISSSHLGLT 302

  Fly   300 KKPPTKPITTSSSSNSPRPSTVEISDTEDGQDPIQTQPSSQLQSLPQSQAQAQALKKVVKTTTVK 364
            ..|.:..:..:|..:....:..::|..:...||..   .|.|.|..:|:.|
Zfish   303 SAPNSNNLLQNSHLHIGHANHTDLSLADLTADPAM---MSLLSSANESELQ-------------- 350

  Fly   365 DMLKAKRDSFLKSQSGTAAVKGVGNGELKCVSTDVSSSDSSDMESEHGRADRQAG---------- 419
            |:::                           ..|.||.|::.......|.:.|.|
Zfish   351 DIMR---------------------------DLDFSSLDAAPQTPPSCRENGQVGMGSSLGNKIG 388

  Fly   420 ----QHGKDGQENLRTADTLLPTTLDADIVTAVNSFKEAVKSRDMCGKK--FNLDVKLSPLLLRV 478
                ..|:.|..:..|    ||..|.|.::..:...:.|.:..|..|:|  |.||  ::.:||.:
Zfish   389 VGGLNRGQAGVVSFPT----LPNGLPAPLIKRIEDLRAASRQFDQEGRKKFFTLD--MNNILLDI 447

  Fly   479 YEAVLCTDRNERNMVFSHIEYQLQLPKYYMLRKGKQVRAKEEKRKSTIMLEKLRRAVAVVMPKAV 543
            ...|.....:.|:.|:||:|..:...|..:|::.|::....:.......|.||:.||..|||:.:
Zfish   448 ELQVQEQPDHVRSEVYSHLEAFVPCNKEALLKRLKKLSLNIQDDSLRTPLLKLKLAVCSVMPEQI 512

  Fly   544 ANYETE--LRTFAEQ--------AAADVNSELPPKM---PRKKFQWTSELRHLLYDVYQARWTSY 595
            |.|..:  .:..|:|        .:.|.:.|.|.|.   |||||.|..:||.||.::.:.:.:.|
Zfish   513 ARYNMDCMAKVAAKQQIEDGEKNGSEDDDEEKPGKRVMGPRKKFIWDDKLRTLLCNLVRVKLSCY 577

  Fly   596 AFLAKRKESLEEFINWYLKEKVVELWPPGWMRLDELQREITRYKNAKLKAKEKPKAPPA------ 654
            . |.:...|:|:::..:::.:|..|||.|||:...|.:| :|..:..|....|.:..|.
Zfish   578 Q-LEQCSLSVEDYLKAFMENEVKPLWPKGWMQTRMLFKE-SRAVHGHLTGLGKKRIVPTPKAAKM 640

  Fly   655 -----SASPKP-VGVVSAPEQMPPASSYLKAVEDPRSRGNSDTDSATSASSNSLKRKLKEMPKQT 713
                 :..|.| ||..||...:|.::....:..:|....:|..:...:.|.:|:.:.|..:
Zfish   641 TDMVWTQRPAPGVGSTSASPALPASACRPSSPSEPICLSDSLDEDLAANSLDSISQALALL---- 701

  Fly   714 SKPPKKKVAKQVPLQPQLTPHPQFQLAPAATAAVSIPAISNNNNHLPHLDTLLSMPSTSAQ---- 774
                 ...||      .|||:       ...||.|.|::..:::.:.|..:.||..:.||:
Zfish   702 -----SNAAK------GLTPN-------NGIAASSAPSVPGSSSGVTHYSSPLSHSTLSAKMEPS 748

  Fly   775 AAALNAAAVAAASTVLDLASPSRKIDLNTSNNFYNLITAASL-AASGNPSPHSGDGQAKVIVGAR 838
            ...|...:..:.|..|.::|||..:   ..:||..|....:| ..||.|:..:|......:..|:
Zfish   749 GIPLGNMSSISTSPSLSISSPSSSM---RGDNFGMLKDGGALQRLSGTPTHRAGISGMSTVQSAK 810

  Fly   839 PSPHVINLDDYQCTSDILQTSKQLAATTTVITAISKAAQTTSVARESSSE--SDGVEIVGVFPAS 901
            |.|.       ...|.:|...::...|..|     |..||..:.:..:::  :.|..:|     |
Zfish   811 PRPP-------PTASPLLPPQQRSYGTMGV-----KMVQTPPLVKNCANKPTTGGNTVV-----S 858

  Fly   902 KPQKKV---QSKPKNKTQNRGRSSLGAVGQV--NGS------------LGYSANNMYIYNSPR-- 947
            :|:...   |..|...|.:...:.|..|..:  |.|            ..:|:|:..|..:||
Zfish   859 QPRVNANPSQQSPPPPTTSSPSTLLAQVKTIPHNQSNFITPMQATLTKSSHSSNSPIIKLTPRPP 923

  Fly   948 ------------TLGPVYDLTDPHIMKTMSNLKEMEKQF-----IQAAFSPNSVKGAS------- 988
                        :..|......|.::.|..........|     .|||...::||..|
Zfish   924 VPTPPPSSSPSPSSSPSLTHPRPQLIPTSHQFTPKSPAFRPPFTTQAAGVTSAVKSISGQASYSF 988

  Fly   989 -GGMGSSAP---------STP-TRQXHSGSAAQQPLPAAVTAFYNQEAM----AAAIVLSTMSHA 1038
             ||..|::|         :|| |....:......|.|:|..|.:||...    |:.:..|:.|.
Zfish   989 AGGHKSASPPVGGASITNTTPMTAPLSAACKDGSPSPSAPLANHNQRQRQVGGASQVAKSSTSR- 1052

  Fly  1039 SPRYDLLANGSVSMSAAQVGASANTLPQVFVKPSLPQ--PSAGGDVVTTTGAARPSTQQLPTKF 1100
                                |||.|||...|...|.|  ||:|.:::   |:..||   ||..|
Zfish  1053 --------------------ASAMTLPSPPVSSHLSQGSPSSGSNLL---GSVPPS---LPLGF 1090

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yem	NP_001263054.1	HUN	129..178	CDD:285888	29/48 (60%)
		UBN_AB	443..633	CDD:290782	56/204 (27%)
ubn2a	XP_005165772.1	HUN	149..198	CDD:285888	29/48 (60%)
		UBN_AB	412..614	CDD:290782	56/204 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	80	1.000	Domainoid score	I8531
eggNOG	1	0.900	-	-		E1_KOG4786
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I4079
OMA	1	1.010	-	-		QHG47800
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002638
OrthoInspector	1	1.000	-	-		otm25217
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21669
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4833
SonicParanoid	1	1.000	-	-		X2355
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	11.050