Protein Alignment yem and Ubn2

DIOPT Version :10

• Sequence 1: NP_001263054.1
• Gene: yem / 43439
• FlyBaseID: FBgn0005596
• Length: 1101
• Species: Drosophila melanogaster
• Sequence 2: NP_796159.3
• Gene: Ubn2 / 320538
• MGIID: 2444236
• Length: 1314
• Species: Mus musculus
• Alignment Length: 1171
• Identity: 270/1171 - (23%)
• Similarity: 438/1171 - (37%)
• Gaps: 293/1171 - (25%)

  Fly    32 PDAASAAPDNSSKPTTKTAKCIRIKLDLFETDSNKYPEFNYSRLLYLEKKKTKKLKQVSTTNGSA 96
            |..:::..:...:|..:|   :|::|.|.:.......||:|..||...::: |||..
Mouse    95 PRESASRAEPPPRPPKET---VRLELVLKDPTDESCVEFSYPELLLCGEQR-KKLVH-------- 147

  Fly    97 STDPFADND---DDVARIVKELEAKYGNSYATGRGKSKKDDYRDIGMGYDESDSFIDNTEAYDEI 158
            :.|||.|..   .:|..:.|:.|.|||.. |....|.:..|..|||.||||:|.||||:|||||:
Mouse   148 TEDPFTDEHKERQEVEMLAKKFEMKYGGK-ARKHRKDRLQDLIDIGFGYDETDPFIDNSEAYDEL 211

  Fly   159 IPEEAETLEGGFYINCGALEFKNLTKKSYTTRTDAIIKMPERSRKRMVSSSSESSSSSSGDDDEN 223
            :|....|..||||||.|.|:|:..:
Mouse   212 VPASLTTKYGGFYINTGTLQFRQAS---------------------------------------- 236

  Fly   224 DDGNNEEDDESDSEDDSEENDESDSEDDSESESLEDEDSAATAKSSSK-------------YKDN 275
               :.||||.:|::...........|||.|.:..:.::.....|...|             :|..
Mouse   237 ---DTEEDDFTDNQKHKPPKVPKIKEDDIEVKKRKRKEEGEKEKKPRKKVPKQLGVVALNSHKSE 298

  Fly   276 HQAKRAK-----VIVTGKSKPSSSSLTSGKKPPTKPITTSSSSNSPRPSTVEISDTED------- 328
            .:.||.|     ..:..|.:....:|.. :..|..|:|.|||| .|:|..|..:..:|
Mouse   299 KKKKRYKDSLSLAAMIRKFQKEKDALKK-ESTPKVPVTPSSSS-LPKPPCVTTALGDDIPDLGLN 361

  Fly   329 GQDP-----IQTQPSSQLQSLPQSQAQAQALKKVVKTTTVKDMLKAKRDSFLKSQSGTAAVKGVG 388
            ..||     :.|......|       :|:...:::.......:|.|..|....|:||
Mouse   362 SADPDLPIFVSTNEHELFQ-------EAENALEMLDDFDFDRLLDATSDGSPLSESG-------- 411

  Fly   389 NGELKCVSTDVSSSDSSDMESEHGRADRQAGQHGKDGQENLRTADTLLPTTLDADIVTAVNSFKE 453
                                .|:|..     .|.....:.:......||..|...:...:...:.
Mouse   412 --------------------GENGNT-----THPTFPSQVVPKVVPTLPEGLPVLLEKRIEDLRV 451

  Fly   454 AVKSRDMCGKK--FNLDV------------KLSPLLLRVYEAVLCTDRNERNMVFSHIEYQLQLP 504
            |.|..|..|:|  |..|:            :|.|::              |:.|:||:|..:...
Mouse   452 AAKLFDEEGRKKFFTQDMNNILLDIELQLQELGPVI--------------RSGVYSHLEAFVPCN 502

  Fly   505 KYYMLRKGKQVRAKEEKRKSTIMLEKLRRAVAVVMPKAVANYETELRTFAEQAAA---------- 559
            |..::::.|::....:..:....|:||:.||:.|||:.:..|:.:.:..::...|
Mouse   503 KETLVKRLKKLHLNVQDDRLREPLQKLKLAVSNVMPEQLFKYQEDCQARSQAKCAKLQADEEREK 567

  Fly   560 ----DVNSELPPKM---PRKKFQWTSELRHLLYDVYQARWTSYAFLAKRKESLEEFINWYLKEKV 617
                |.:.|.|.|.   |||||.|...:|.||.::.:.:...|.....:.:|.|:::..:::.:|
Mouse   568 NGSDDDDDEKPGKRVIGPRKKFHWDDTIRTLLCNLVEIKLGCYELEPNKSQSAEDYLKSFMETEV 632

  Fly   618 VELWPPGWMRLDELQREITRYKNAKLKAKEKPKAPPASASPKPVGVVSAPEQMPPASSYLKAVED 682
            ..|||.|||:...|.:|.....|....|..|.|..|||   ||.....:|::.|.|.:.:.|
Mouse   633 KPLWPKGWMQARMLFKESRSVHNHLTSAPAKKKVIPAS---KPKVKECSPKKDPKAPASVVA--- 691

  Fly   683 PRSRGNSDTDSATS--ASSNSLKRKLKEMPKQTSKPPKKKVAKQVPLQPQLT-PHPQFQLAPAAT 744
              |.|...|.|:||  ||::|           :|.|.::.:.....|...|: |.....|...|.
Mouse   692 --SGGGPSTSSSTSIVASASS-----------SSAPAQETICLDDSLDEDLSFPSASLDLVSEAL 743

  Fly   745 AAVSIPAISNNNNHLPHLDTLLSMPSTSAQAAALNAAAVAAASTVLDLASPSRKIDLNTSNNFYN 809
            |.:      ||.|..|.:.:.|::|:|..: ..|....:|:..:.|.||:| :|:|...:.:..:
Mouse   744 AVI------NNGNKGPSVGSRLNVPTTKPR-PGLREEKLASIMSKLPLATP-KKLDSTQTAHSSS 800

  Fly   810 LITAASLAASGNPSP-------HSGDGQAKVIVGARPSPHVINLDDY--QCTSDILQTSKQLAAT 865
            ||     |....|.|       |:|.... :|.|:......::|:..  :.....||.|.|:.|:
Mouse   801 LI-----AGHTGPVPKKPQDLAHTGISSG-LIAGSSIQNPKVSLEPLPARLLQQGLQRSSQIHAS 859

  Fly   866 TTVITAISKA---------AQTTSVARESSS--------ESDGVEIVGVFPASKPQKKVQSKPKN 913
            ::..|.:|.:         |..||.|:::||        :...|:...|.|......|.|:.|..
Mouse   860 SSSQTHVSSSQAQAAASSHALGTSEAQDASSLTQVTKVHQHSAVQQNYVSPLQATISKSQTNPVV 924

  Fly   914 KTQNRGRSSLGAVGQVNGSLGYSANNMYIYNSP-RTLGPVYDLTDPHIM--------KTMSN--L 967
            |..|..:.|      .:..|..:::...:|..| .|..|......||.:        .|.||  .
Mouse   925 KLSNNPQLS------CSSQLLKTSDKPLMYRLPLSTPSPGNGSQGPHPLVSRTAPSTTTSSNYLA 983

  Fly   968 KEMEKQFIQAAF-SPNSVKGASGGMGSSAPSTPTRQXHSGSAAQQPLPAAVTAFYNQEAMAAAIV 1031
            |.|..|.....| ||.|:..:.....|..|:|          :.:|||
Mouse   984 KAMVSQISTQGFKSPFSMAASPKLAASPKPAT----------SPKPLP----------------- 1021

  Fly  1032 LSTMSHASPRYDLLANGSVSMSAAQVGASANTLPQVFVKPSLPQPSAGGDVVTTTGAARPSTQQL 1096
             |.....||:..|.|..|:  |..|:..| |..|:..|.||...|:      |....:..||...
Mouse  1022 -SPKPSVSPKPSLSAKPSI--STKQISKS-NPAPKPAVCPSSSSPN------TLVAQSSHSTSNN 1076

  Fly  1097 P 1097
            |
Mouse  1077 P 1077

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yem	NP_001263054.1	HUN	127..178	CDD:462581	28/50 (56%)
		UBN_AB	436..633	CDD:464081	53/227 (23%)
Ubn2	NP_796159.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..113		3/20 (15%)
		HUN	180..231	CDD:462581	28/50 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	236..288		11/94 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	322..345		9/24 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	400..424		8/56 (14%)
		UBN_AB	434..648	CDD:464081	53/227 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	559..584		4/24 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	657..709		20/59 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	785..818		9/38 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	849..893		13/43 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	948..975		6/26 (23%)
		Herpes_BLLF1	<954..>1218	CDD:282904	39/161 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1003..1185		25/112 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1288..1314