DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pdhb and MAB1

DIOPT Version :9

Sequence 1:	NP_651668.1	Gene:	Pdhb / 43437	FlyBaseID:	FBgn0039635	Length:	365	Species:	Drosophila melanogaster
Sequence 2:	NP_199898.1	Gene:	MAB1 / 835157	AraportID:	AT5G50850	Length:	363	Species:	Arabidopsis thaliana

Alignment Length:	353	Identity:	236/353 - (66%)
Similarity:	283/353 - (80%)	Gaps:	5/353 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLRTRLIQAASSAQRA----FSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDG 61
            :||.|.|..||:.:|.    .|....|..||:||||||||||:|:|::.|.:||::||||.||.|
plant     4 ILRQRAIDGASTLRRTRFALVSARSYAAGAKEMTVRDALNSAIDEEMSADPKVFVMGEEVGQYQG 68

  Fly    62 AYKVSRGLWKKYGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHIINSAAKT 126
            |||:::||.:|||.:||.||||||.||.||.||||.|||:||.||||:||||||||||||||||:
plant    69 AYKITKGLLEKYGPERVYDTPITEAGFTGIGVGAAYAGLKPVVEFMTFNFSMQAIDHIINSAAKS 133

  Fly   127 FYMSAGAVNVPIVFRGPNGAASGVAAQHSQCFAAWYAHCPGLKVLSPYDAEDARGLLKSAIRDPD 191
            .|||||.:|||||||||||||:||.||||||:|||||..||||||:||.|||||||||:||||||
plant   134 NYMSAGQINVPIVFRGPNGAAAGVGAQHSQCYAAWYASVPGLKVLAPYSAEDARGLLKAAIRDPD 198

  Fly   192 PVVFLENELVYGTAFPVADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVETSLLAAAELAKKG 256
            |||||||||:||.:||:::...|..|.:||||||:.|.|||:|:|..||.|..:|.||.:||::|
plant   199 PVVFLENELLYGESFPISEEALDSSFCLPIGKAKIEREGKDVTIVTFSKMVGFALKAAEKLAEEG 263

  Fly   257 IEAEVINLRSIRPLDTATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTFFELDAPVWRC 321
            |.|||||||||||||.|||.||||||..|||||.|:|||||.|||||.::| ::|..|||||.|.
plant   264 ISAEVINLRSIRPLDRATINASVRKTSRLVTVEEGFPQHGVCAEICASVVE-ESFSYLDAPVERI 327

  Fly   322 AGVDVPMPYAKTLEAHALPRVQDLVEAT 349
            ||.|||||||..||..|||:::|:|.|:
plant   328 AGADVPMPYAANLERLALPQIEDIVRAS 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pdhb	NP_651668.1	PLN02683	2..352	CDD:215368	236/352 (67%)
		TPP_PYR_E1-PDHc-beta_like	33..199	CDD:132919	127/165 (77%)
		Transketolase_C	222..340	CDD:280875	78/117 (67%)
MAB1	NP_199898.1	PLN02683	11..363	CDD:215368	232/346 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	284	1.000	Domainoid score	I384
eggNOG	1	0.900	-	-		E1_COG0022
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H712
Inparanoid	1	1.050	463	1.000	Inparanoid score	I361
OMA	1	1.010	-	-		QHG53958
OrthoDB	1	1.010	-	-		D875272at2759
OrthoFinder	1	1.000	-	-		FOG0002922
OrthoInspector	1	1.000	-	-		oto3335
orthoMCL	1	0.900	-	-		OOG6_101309
Panther	1	1.100	-	-	LDO	PTHR11624
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2740
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840