Protein Alignment Pdhb and BCKDHB

DIOPT Version :9

• Sequence 1: NP_651668.1
• Gene: Pdhb / 43437
• FlyBaseID: FBgn0039635
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_000047.1
• Gene: BCKDHB / 594
• HGNCID: 987
• Length: 392
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 119/342 - (34%)
• Similarity: 178/342 - (52%)
• Gaps: 17/342 - (4%)

  Fly    15 RAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKKYGDKRVI 79
            |.:..:||      |.:..::.||||:.||:|....|.||:|| :.|.::.:.||..|||..||.
Human    63 REYGQTQK------MNLFQSVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVF 120

  Fly    80 DTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHIINSAAKTFYMSAGAVNV-PIVFRGP 143
            :||:.|.|..|..:|.|:.|...:.|....::...|.|.|:|.|||..|.|....|. .:..|.|
Human   121 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSP 185

  Fly   144 NGAASGVAAQHSQCFAAWYAHCPGLKVLSPYDAEDARGLLKSAIRDPDPVVFLENELVYGTAFPV 208
            .|.....|..|||...|::|||||:||:.|.....|:|||.|.|.|.:|.:|.|.:::|..|
Human   186 WGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAA--- 247

  Fly   209 ADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVETSLLAAAELAKK--GIEAEVINLRSIRPLD 271
            |:.|..:.:.:|:.:|:|::.|.|:||||....|.. :...|.:||:  |:..|||:||:|.|.|
Human   248 AEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHV-IREVASMAKEKLGVSCEVIDLRTIIPWD 311

  Fly   272 TATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTFFELDAPVWRCAGVDVPMPYAKTLEA 336
            ..||..||.||..|:.........|..:||.:.:.| :.|..|:||:.|..|.|.|.|:  ..|.
Human   312 VDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQE-ECFLNLEAPISRVCGYDTPFPH--IFEP 373

  Fly   337 HALPRVQDLVEATLKVL 353
            ..:|......:|..|::
Human   374 FYIPDKWKCYDALRKMI 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdhb	NP_651668.1	PLN02683	2..352	CDD:215368	118/339 (35%)
		TPP_PYR_E1-PDHc-beta_like	33..199	CDD:132919	65/166 (39%)
		Transketolase_C	222..340	CDD:280875	42/119 (35%)
BCKDHB	NP_000047.1	PTZ00182	66..390	CDD:185502	118/337 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D314250at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820