Protein Alignment Pdhb and pdb1

DIOPT Version :9

• Sequence 1: NP_651668.1
• Gene: Pdhb / 43437
• FlyBaseID: FBgn0039635
• Length: 365
• Species: Drosophila melanogaster
• Sequence 2: NP_596272.1
• Gene: pdb1 / 2540273
• PomBaseID: SPBC30D10.13c
• Length: 366
• Species: Schizosaccharomyces pombe
• Alignment Length: 345
• Identity: 217/345 - (62%)
• Similarity: 268/345 - (77%)
• Gaps: 3/345 - (0%)

  Fly    10 ASSAQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKKYG 74
            :|:..:.:|:|...:  |:||||||||||:::|:.||||||::|||||||:||||:||||..|:|
pombe    21 SSTIAKRYSSSSNGV--KEMTVRDALNSAMEEEMKRDDRVFLIGEEVAQYNGAYKISRGLLDKFG 83

  Fly    75 DKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHIINSAAKTFYMSAGAVNVPIV 139
            .|||||||||||||.|:|.|||.|||||:|||||:||||||||||:||||:|.|||.|....|||
pombe    84 PKRVIDTPITEMGFTGLATGAAFAGLRPICEFMTFNFSMQAIDHIVNSAARTLYMSGGIQACPIV 148

  Fly   140 FRGPNGAASGVAAQHSQCFAAWYAHCPGLKVLSPYDAEDARGLLKSAIRDPDPVVFLENELVYGT 204
            ||||||.|:.|||||||.||.||...|||||:|||.|||||||||:|||||:|||.||||::||.
pombe   149 FRGPNGPAAAVAAQHSQHFAPWYGSIPGLKVVSPYSAEDARGLLKAAIRDPNPVVVLENEILYGK 213

  Fly   205 AFPVADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVETSLLAAAEL-AKKGIEAEVINLRSIR 268
            .||::.....:||::|.|.|||.|||||||:|..|.:|.|:|.||.:| |..|:|||||||||||
pombe   214 TFPISKEALSEDFVLPFGLAKVERPGKDITIVGESISVVTALEAADKLKADYGVEAEVINLRSIR 278

  Fly   269 PLDTATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTFFELDAPVWRCAGVDVPMPYAKT 333
            |||..||.|||:||:.:|||:..:.|||:|:||.|:|||...|..|||||.|.:..||||||:..
pombe   279 PLDINTIAASVKKTNRIVTVDQAYSQHGIGSEIAAQIMESDAFDYLDAPVERVSMADVPMPYSHP 343

  Fly   334 LEAHALPRVQDLVEATLKVL 353
            :||.::|....:|.|..|.|
pombe   344 VEAASVPNADVVVAAAKKCL 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pdhb	NP_651668.1	PLN02683	2..352	CDD:215368	215/342 (63%)
		TPP_PYR_E1-PDHc-beta_like	33..199	CDD:132919	125/165 (76%)
		Transketolase_C	222..340	CDD:280875	70/118 (59%)
pdb1	NP_596272.1	PLN02683	25..364	CDD:215368	216/341 (63%)
		TPP_PYR_E1-PDHc-beta_like	42..208	CDD:132919	125/165 (76%)
		Transketolase_C	231..355	CDD:280875	71/123 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	277	1.000	Domainoid score	I311
eggNOG	1	0.900	-	-		E1_COG0022
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H712
Inparanoid	1	1.050	428	1.000	Inparanoid score	I329
OMA	1	1.010	-	-		QHG53958
OrthoFinder	1	1.000	-	-		FOG0002922
OrthoInspector	1	1.000	-	-		oto100704
orthoMCL	1	0.900	-	-		OOG6_101309
Panther	1	1.100	-	-	LDO	PTHR11624
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R864
SonicParanoid	1	1.000	-	-		X2740
TreeFam	1	0.960	-	-
	14	13.860