Protein Alignment alpha-Man-Ib and MNS1

DIOPT Version :9

• Sequence 1: NP_651667.1
• Gene: alpha-Man-Ib / 43436
• FlyBaseID: FBgn0039634
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: NP_012665.3
• Gene: MNS1 / 853595
• SGDID: S000003892
• Length: 549
• Species: Saccharomyces cerevisiae
• Alignment Length: 533
• Identity: 198/533 - (37%)
• Similarity: 280/533 - (52%)
• Gaps: 83/533 - (15%)

  Fly   209 VSFKEHLKKIKPILAKGQHFHGATNERQSAVVAAFKHSWAGYKKYAWGHDNLKPISQYSHEW--- 270
            |.:.||.::..|         || .|.:..:.:.|..||..|.|:.||:|...||...||..
Yeast    22 VPWYEHFERKSP---------GA-GEMRDRIESMFLESWRDYSKHGWGYDVYGPIEHTSHNMPRG 76

  Fly   271 -FGLGLTIVDSLDTMYIM---------GLDDEFKEGRDWVEQSLRFDTKRDVNLFEVTIRVLGGL 325
             ..||..||||:||:.:|         ..:.|.:....|:...|.||...:||:||.|||:||||
Yeast    77 NQPLGWIIVDSVDTLMLMYNSSTLYKSEFEAEIQRSEHWINDVLDFDIDAEVNVFETTIRMLGGL 141

  Fly   326 LSAYHLS------GDTMFLAKAAELGNRLLPAFQS-PSNIPYSDVNLGDLSAHSPKWSPD---SS 380
            |||||||      ..|::|.||.:||:||..||.| .:.||||.:||.  |..:.|...|   ||
Yeast   142 LSAYHLSDVLEVGNKTVYLNKAIDLGDRLALAFLSTQTGIPYSSINLH--SGQAVKNHADGGASS 204

  Fly   381 TSEVTTIQLEFRDLSRSTNISIYEQVAHKVNE---KVHDLEKNH-GLVPIFINANTGTFRNYATI 441
            |:|.||:|:||:.|:..|....|.::..:|.|   |.:||...: |||||:...:||.| ..:||
Yeast   205 TAEFTTLQMEFKYLAYLTGNRTYWELVERVYEPLYKNNDLLNTYDGLVPIYTFPDTGKF-GASTI 268

  Fly   442 SLGARGDSYYEYLLKQWIQTGRKDNDNLILD-YMQAVDGVLTQLMRRT-PREHWVYIGELING-- 502
            ..|:||||:|||||||::.|    ::.|..| |.::::|:...|:.:: |...| ||||...|
Yeast   269 RFGSRGDSFYEYLLKQYLLT----HETLYYDLYRKSMEGMKKHLLAQSKPSSLW-YIGEREQGLH 328

  Fly   503 KDFKPKMDHLTCYLPGTLILGHQNGMP----------------DSHLILARDLLDTCYQTYMMNP 551
            ....||||||.|::.|.|..|...|:.                .|...||:.:.|||||.|..:.
Yeast   329 GQLSPKMDHLVCFMGGLLASGSTEGLSIHEARRRPFFSLSLERKSDWDLAKGITDTCYQMYKQSS 393

  Fly   552 THLAAEISYF--ALTEKDD------QDIYVKPNDAHNLLRPEFVESLYYFYSITGNRTYQDMGWK 608
            :.||.||..|  ...::|.      .|.:|||.|.|||.|||.|||:.:.|.::.:..|::.|.:
Yeast   394 SGLAPEIVVFNDGNIKQDGWWRSSVGDFFVKPLDRHNLQRPETVESIMFMYHLSHDHKYREWGAE 458

  Fly   609 IFQAFETHAKVNAG------YTSMGNVKNTQSTRLRDLMESFWMSETLKYFYLLFSDDRKEIDLE 667
            |..:|..:..|:..      :||:.:. .|..|:..:.|||||::|||||.|:||.|   |.||.
Yeast   459 IATSFFENTCVDCNDPKLRRFTSLSDC-ITLPTKKSNNMESFWLAETLKYLYILFLD---EFDLT 519

  Fly   668 QWVFNSEGHPLPV 680
            :.|||:|.||.||
Yeast   520 KVVFNTEAHPFPV 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ib	NP_651667.1	Glyco_hydro_47	242..680	CDD:279825	189/498 (38%)
MNS1	NP_012665.3	Glyco_hydro_47	45..532	CDD:396217	189/498 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344166
Domainoid	1	1.000	265	1.000	Domainoid score	I293
eggNOG	1	0.900	-	-		E1_KOG2431
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	268	1.000	Inparanoid score	I608
Isobase	1	0.950	-	0	Normalized mean entropy	S1238
OMA	1	1.010	-	-		QHG54359
OrthoFinder	1	1.000	-	-		FOG0002927
OrthoInspector	1	1.000	-	-		otm46690
orthoMCL	1	0.900	-	-		OOG6_100239
Panther	1	1.100	-	-	LDO	PTHR11742
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R728
SonicParanoid	1	1.000	-	-		X2293
TreeFam	1	0.960	-	-
	15	14.740