DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment alpha-Man-Ib and MNS2

DIOPT Version :9

Sequence 1:	NP_651667.1	Gene:	alpha-Man-Ib / 43436	FlyBaseID:	FBgn0039634	Length:	685	Species:	Drosophila melanogaster
Sequence 2:	NP_566675.1	Gene:	MNS2 / 821668	AraportID:	AT3G21160	Length:	572	Species:	Arabidopsis thaliana

Alignment Length:	462	Identity:	201/462 - (43%)
Similarity:	290/462 - (62%)	Gaps:	36/462 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   234 ERQSAVVAAFKHSWAGYKKYAWGHDNLKPISQYSHEWF-GLGLTIVDSLDTMYIMGLDDEFKEGR 297
            :|...|..|..|:|:.|:|||||.|.|:|.::...:.| |||.|::|:|||:||||||::|::.|
plant    97 QRMQRVKEAMVHAWSSYEKYAWGQDELQPQTKDGVDSFGGLGATMIDALDTLYIMGLDEQFQKAR 161

  Fly   298 DWVEQSLRFDTKRDVNLFEVTIRVLGGLLSAYHLSGDTMFLAKAAELGNRLLPAFQSPSNIPYSD 362
            :||..||.||.....::||.||||:|||||||.||||.:||.||.::.:|||||:.:.|.|||:.
plant   162 EWVASSLDFDKDYAASMFETTIRVVGGLLSAYDLSGDKIFLEKAMDIADRLLPAWDTQSGIPYNI 226

  Fly   363 VNLGDLSAHSPKWS-PDSSTSEVTTIQLEFRDLSRSTNISIYEQVAHKVNEKVHDLEKN---HGL 423
            :||...:||:|.|: .||..::..|.||||..||:.|....|:|   ||.:.:..|.||   .||
plant   227 INLKHGNAHNPTWAGGDSILADSGTEQLEFIALSQRTGDPKYQQ---KVEKVISVLNKNFPADGL 288

  Fly   424 VPIFINANTGTFRNYATISLGARGDSYYEYLLKQWIQTGRKDNDNLILDYM----QAVDGVLTQL 484
            :||:||.:|.. .:.:||:.||.|||:||||||.|: .|.|  .:.:..|.    ::::|:|:.:
plant   289 LPIYINPDTAN-PSQSTITFGAMGDSFYEYLLKVWV-FGNK--TSAVKHYRDMWEKSMNGLLSLV 349

  Fly   485 MRRTPREHWVYIGELINGKDFKPKMDHLTCYLPGTLILGHQNGMPD-----SHLILARDLLDTCY 544
            .:.||.. :.||.|. :|.....|||.|.|:.||.|.|| .:|..|     ..|.||.:|..|||
plant   350 KKSTPLS-FTYICEK-SGNSLIDKMDELACFAPGMLALG-ASGYSDPAEGKKFLTLAEELAWTCY 411

  Fly   545 QTYMMNPTHLAAEISYFALTEKDDQDIYVKPNDAHNLLRPEFVESLYYFYSITGNRTYQDMGWKI 609
            ..|...||.||.| :||..:..|     :....:.|:||||.||||:|.:.:|||:|||:.||.|
plant   412 NFYQSTPTKLAGE-NYFFNSGSD-----MSVGTSWNILRPETVESLFYLWRLTGNKTYQEWGWNI 470

  Fly   610 FQAFETHAKVNAGYTSMGNVKNTQSTRLRD-LMESFWMSETLKYFYLLFSDDRKEIDLEQWVFNS 673
            |:|||.::::.:||..:.:|    :|.::| .|:||:::|||||.||||| ....|.|::||||:
plant   471 FEAFEKNSRIESGYVGLKDV----NTGVKDNKMQSFFLAETLKYLYLLFS-PTTVIPLDEWVFNT 530

  Fly   674 EGHPLPV 680
            |.|||.:
plant   531 EAHPLKI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ib	NP_651667.1	Glyco_hydro_47	242..680	CDD:279825	199/452 (44%)
MNS2	NP_566675.1	Glyco_hydro_47	105..537	CDD:279825	199/452 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54359
OrthoDB	1	1.010	-	-		D693882at2759
OrthoFinder	1	1.000	-	-		FOG0002927
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100239
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830