Protein Alignment alpha-Man-Ib and man1b1b

DIOPT Version :9

• Sequence 1: NP_651667.1
• Gene: alpha-Man-Ib / 43436
• FlyBaseID: FBgn0039634
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: NP_001093449.1
• Gene: man1b1b / 556237
• ZFINID: ZDB-GENE-070705-482
• Length: 632
• Species: Danio rerio
• Alignment Length: 721
• Identity: 299/721 - (41%)
• Similarity: 404/721 - (56%)
• Gaps: 146/721 - (20%)

  Fly     7 ITLTL-PPGSAATTDERGRKSLRRAWNQLPRCQRNLIILGITGFCVTVLLC-------------- 56
            ::||| ..||.:.:.:..|:|..|.|.||.|.||:||:|.:    :.:|:|
Zfish    10 VSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTL----MLLLVCGIATSPTLIGHWRG 70

  Fly    57 LSGDQLLAASLKDVDTKAEVAAYQMPLPNPHHHPGVDKDVPKDTAAVPVPADKRAP--RVEAVSD 119
            ::||.:..:.:  ||.|.|   |:..||.|   |...||.           |:|..  ..:.:..
Zfish    71 MNGDDVKNSFV--VDLKNE---YRSILPEP---PSERKDF-----------DRRGAFGLEKLLQG 116

  Fly   120 KFNELVAYGEANSAENVARLPETVAAEGLPQASAMAVALPPPDSNKEQDIGGIDILNNVEEPVAQ 184
            |.|.....|:.|.                                      |:|:.|
Zfish   117 KVNVSGVLGDQNH--------------------------------------GLDLKN-------- 135

  Fly   185 DPAEPLSEGEQLEQAIKNPLTLGGVSFKEHLKKIKPILAKGQHFHGATNE--------------- 234
              |:..|||:                        |||::    :.||..|
Zfish   136 --ADKGSEGQ------------------------KPIIS----WRGAVIEEEQASDTDTKDTENQ 170

  Fly   235 -----------RQSAVVAAFKHSWAGYKKYAWGHDNLKPISQYSHEWFGLGLTIVDSLDTMYIMG 288
                       |..||..||:|:|.|||.:|||||.|||||:...||||||||::|:||||:|:|
Zfish   171 GDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILG 235

  Fly   289 LDDEFKEGRDWVEQSLRFDTKRDVNLFEVTIRVLGGLLSAYHLSGDTMFLAKAAELGNRLLPAFQ 353
            |.:||.|.|:||.:.|.||...||||||.|||:||||||.|||:||.:||.||.|:|.||:|||.
Zfish   236 LQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFS 300

  Fly   354 SPSNIPYSDVNLGDLSAHSPKWSPDSSTSEVTTIQLEFRDLSRSTNISIYEQVAHKVNEKVHDLE 418
            :||.|||||||:|..:||.|:|:.||:.:|||:||||||:|||.|....|:....:|.::||.|:
Zfish   301 TPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLD 365

  Fly   419 -KNHGLVPIFINANTGTFRNYATISLGARGDSYYEYLLKQWIQTGRKDNDNLILDYMQAVDGVLT 482
             |..||||:|||.|.|.|.:....:||||.|||||||||||||.||.:.: |:.||:|||:||..
Zfish   366 GKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQE-LLEDYLQAVEGVKK 429

  Fly   483 QLMRRTPREHWVYIGELINGKDFKPKMDHLTCYLPGTLILGHQNGMPDSHLILARDLLDTCYQTY 547
            .|::::......::|||.:| .|.||||||.|:|||||.||...|:|..|:.||:.|::||||.|
Zfish   430 NLLKKSTPLGLTFVGELSHG-HFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMY 493

  Fly   548 MMNPTHLAAEISYFALTEKDDQDIYVKPNDAHNLLRPEFVESLYYFYSITGNRTYQDMGWKIFQA 612
            ....|.|:.||::|.:.:...||:.||..|.|||||||.||||:|.|.:|.::.||..||:|.|.
Zfish   494 AQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQN 558

  Fly   613 FETHAKV-NAGYTSMGNVKNTQSTRLRDLMESFWMSETLKYFYLLFSDDRKEIDLEQWVFNSEGH 676
            |..:.:| ..||||:.||::...|..||.||||::.|||||||||||:|...|.|:::|||:|.|
Zfish   559 FNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAH 623

  Fly   677 PLPVYP 682
            ||||:|
Zfish   624 PLPVWP 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ib	NP_651667.1	Glyco_hydro_47	242..680	CDD:279825	242/439 (55%)
man1b1b	NP_001093449.1	Glyco_hydro_47	189..627	CDD:279825	242/439 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582038
Domainoid	1	1.000	512	1.000	Domainoid score	I309
eggNOG	1	0.900	-	-		E1_KOG2431
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	525	1.000	Inparanoid score	I1206
OMA	1	1.010	-	-		QHG54359
OrthoDB	1	1.010	-	-		D263455at33208
OrthoFinder	1	1.000	-	-		FOG0002927
OrthoInspector	1	1.000	-	-		otm25497
orthoMCL	1	0.900	-	-		OOG6_100239
Panther	1	1.100	-	-	LDO	PTHR11742
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R728
SonicParanoid	1	1.000	-	-		X2293
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800