Protein Alignment alpha-Man-Ib and man1a2

DIOPT Version :10

• Sequence 1: NP_651667.1
• Gene: alpha-Man-Ib / 43436
• FlyBaseID: FBgn0039634
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: NP_001243551.1
• Gene: man1a2 / 335538
• ZFINID: ZDB-GENE-070912-390
• Length: 645
• Species: Danio rerio
• Alignment Length: 572
• Identity: 192/572 - (33%)
• Similarity: 314/572 - (54%)
• Gaps: 55/572 - (9%)

  Fly   156 VALPPPDSNKEQDIGGIDILNNV---------------EEPVAQDPAEPLSEGEQ----LEQAIK 201
            |.:|..::.||...|...:::.|               .:.:..|....|.|.::    .::.:|
Zfish    73 VLIPHIETEKESRHGSRQVIHGVGAHDEHRHREEEESLRDKIRADHERALQEAKEKLRKSKEELK 137

  Fly   202 NPLTLGGVSFKEHLKK------IKPI-------LAKGQHFHGATNERQSAVVAAFKHSWAGYKKY 253
            ..:........|.|||      :.|:       :..|......|.|::..:....||:|..|::|
Zfish   138 AEIQTAKAKVSEDLKKKDGPKPLPPVPMPKLVGVNDGDPGDPDTKEKRDKIREMMKHAWDSYRQY 202

  Fly   254 AWGHDNLKPISQYSHEW--FG---LGLTIVDSLDTMYIMGLDDEFKEGRDWVEQSLRFDTKRDVN 313
            .|||:.|||:::..|..  ||   :|.||||:|||:|||||.||||:|::|:||:|.|....:|:
Zfish   203 GWGHNELKPLAKKGHSTNIFGNSQMGATIVDALDTLYIMGLHDEFKDGQEWIEQNLDFSVNAEVS 267

  Fly   314 LFEVTIRVLGGLLSAYHLSGDTMFLAKAAELGNRLLPAFQSPSNIPYSDVNLGDLSAHSPKWSPD 378
            :|||.||.:||||:||:|||..:|..||.:|..:|||||.:|:.||::.|||......:..|:..
Zfish   268 VFEVNIRFIGGLLAAYYLSGQEVFKLKAVQLAEKLLPAFNTPTGIPWAMVNLKSGVGRNWGWASG 332

  Fly   379 SST--SEVTTIQLEFRDLSRST-NISIYEQVAHKVNEKVHDLEKNHGLVPIFINANTGTFRNYAT 440
            .|:  :|..|:.:||..|:..| |.:.|::|.| :.:.:..:::.:||.|.::|..||.:..:.|
Zfish   333 GSSILAEFGTLHMEFVHLTYLTGNPAYYQKVMH-IRKLLAKMDRPNGLYPNYLNPRTGRWGQHHT 396

  Fly   441 ISLGARGDSYYEYLLKQWIQTGRKDNDNLILDYMQAVDGVLTQLMRRTPREHWVYIGELINGKDF 505
             |:|..|||:||||||.|:.:.:.|.: ....|..|::.:...|:|:: .....:|||..|| ..
Zfish   397 -SVGGLGDSFYEYLLKAWLMSDKTDAE-ARKTYDDAIEAIERHLIRKS-NGGLTFIGEWKNG-HL 457

  Fly   506 KPKMDHLTCYLPGTLILGHQNGMPDS----HLILARDLLDTCYQTYMMNPTHLAAEISYFALTEK 566
            :.||.||||:..|...|| .:|.||.    :|.|..::..||:::|......|..|...|   :.
Zfish   458 ERKMGHLTCFAGGMFALG-ADGSPDDKAGHYLQLGAEIAHTCHESYDRTVLKLGPEAFKF---DS 518

  Fly   567 DDQDIYVKPNDAHNLLRPEFVESLYYFYSITGNRTYQDMGWKIFQAFETHAKVNAGYTSMGNVKN 631
            ..:.:.|:.|:.:.:||||.:|:.:|.:..|.:..|:..||:..||.:.|.:|:.|::.:.:|.:
Zfish   519 GLEAVAVRQNEKYYILRPEVIETYWYMWRFTHDPKYRQWGWEAAQAIDKHCRVSGGFSGVKDVYS 583

  Fly   632 TQSTRLRDLMESFWMSETLKYFYLLFSDDRKEIDLEQWVFNSEGHPLPVYPL 683
            :..| ..|:.:||:::|||||.|||||.| :.:.||.||||:|.|||||..|
Zfish   584 SNPT-YDDVQQSFFLAETLKYLYLLFSSD-ELLPLENWVFNTEAHPLPVLHL 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ib	NP_651667.1	Glyco_hydro_47	242..680	CDD:460241	171/449 (38%)
man1a2	NP_001243551.1	Glyco_hydro_47	191..630	CDD:460241	171/449 (38%)