Protein Alignment alpha-Man-Ib and Man1a1

DIOPT Version :9

• Sequence 1: NP_651667.1
• Gene: alpha-Man-Ib / 43436
• FlyBaseID: FBgn0039634
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: XP_006256559.1
• Gene: Man1a1 / 294410
• RGDID: 1310891
• Length: 746
• Species: Rattus norvegicus
• Alignment Length: 717
• Identity: 217/717 - (30%)
• Similarity: 350/717 - (48%)
• Gaps: 112/717 - (15%)

  Fly     1 MKDGGHITLTLPPGSAATTD------ERGRKSLRRAWNQLPRCQRNLIILGITGFCVTVLLCLSG 59
            |..||.:.|...||......      ..|||....|..:|  .::.:::|..:.|   :.||...
  Rat    92 MPVGGLLPLFSSPGGGGLGGGLGGGLGGGRKGSGPAAFRL--TEKFVLLLVFSAF---ITLCFGA 151

  Fly    60 DQLLAASLKDVDTKAEVAAYQMPL--PNPHHHPGV---------------DKDVPKDTAAVPVPA 107
            ...|..|.|   ..:.|..:..|.  |...|.||:               ::.||.|..|   ..
  Rat   152 IFFLPDSSK---LLSGVLFHSNPALQPPAEHKPGLGARAEDAAEGRVRHREEGVPGDPGA---GL 210

  Fly   108 DKRAPRVEAVSDKFNELVAYGEANSAENVARLPETVAAEGLPQASAMAVALPPPDSNKEQDIGG- 171
            :....|:     :.|...|..||.  |.:.:|||.:..:.|.:...:|     .|..:::|:.|
  Rat   211 EDNLARI-----RENHERALREAK--ETLQKLPEEIQRDILLEKEKVA-----QDQLRDKDLFGG 263

  Fly   172 ---IDILNNVEEPVAQDPAEPLSEGEQLEQAIKNPLTLGGVSFKEHLKKIKPILAKGQHFHGATN 233
               :|.|    .|:..:..||                 ...:.:|...|||.::|
  Rat   264 LPKVDFL----PPIGVENREP-----------------ADATIREKRSKIKEMMA---------- 297

  Fly   234 ERQSAVVAAFKHSWAGYKKYAWGHDNLKPISQYSH--EWFG--LGLTIVDSLDTMYIMGLDDEFK 294
                       |:|..||:||||.:.|||||:..|  ..||  .|.||||:|||::|||:..||:
  Rat   298 -----------HAWNNYKRYAWGLNELKPISKEGHSSSLFGNIKGATIVDALDTLFIMGMKTEFQ 351

  Fly   295 EGRDWVEQSLRFDTKRDVNLFEVTIRVLGGLLSAYHLSGDTMFLAKAAELGNRLLPAFQSPSNIP 359
            |.:.|:::.|.|:...:|::|||.||.:|||||||:|||:.:|..||.|||.:|||||.|||.||
  Rat   352 EAKSWIKKYLDFNVNAEVSVFEVNIRFVGGLLSAYYLSGEEIFRKKAVELGVKLLPAFHSPSGIP 416

  Fly   360 YSDVNLGDLSAHSPKWSPDSST--SEVTTIQLEFRDLSRSTNISIYEQVAHKVNEKVHDLEKNHG 422
            ::.:|:......:..|:...|:  :|..|:.|||..|:..:...::.:....:...::.|:|..|
  Rat   417 WALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHLAHLSGNPVFAEKVMNIRTVLNKLDKPEG 481

  Fly   423 LVPIFINANTGTFRNYATISLGARGDSYYEYLLKQWIQTGRKDNDNLILDYMQAVDGVLTQLMRR 487
            |.|.::|.::|.:..: .:|:|..|||:||||||.|:.:.:.|.:...: |..||..:.|.|:|:
  Rat   482 LYPNYLNPSSGQWGQH-HVSVGGLGDSFYEYLLKAWLMSDKTDLEAKKM-YFDAVQAIETHLIRK 544

  Fly   488 TPREHWVYIGELINGKDFKPKMDHLTCYLPGTLILGHQNGMPDS----HLILARDLLDTCYQTYM 548
            : .....||.|...|. .:.||.||||:..|...|| .:|.|::    :|.|..::..||:::|.
  Rat   545 S-SGGLTYIAEWKGGL-LEHKMGHLTCFAGGMFALG-ADGAPEARAQHYLELGAEIARTCHESYN 606

  Fly   549 MNPTHLAAEISYFALTEKDDQDIYVKPNDAHNLLRPEFVESLYYFYSITGNRTYQDMGWKIFQAF 613
            .....|..|...|   :...:.|..:.|:.:.:||||.:|:..|.:.:|.:..|:...|:..:|.
  Rat   607 RTYVKLGPEAFRF---DGGVEAIATRQNEKYYILRPEVIETYMYMWRLTHDPKYRTWAWEAVEAL 668

  Fly   614 ETHAKVNAGYTSMGNVKNTQSTRLRDLMESFWMSETLKYFYLLFSDDRKEIDLEQWVFNSEGHPL 678
            |:|.:||.||:.:.:|.....: ..|:.:||:::|||||.||:|||| ..:.||.|:||:|.||.
  Rat   669 ESHCRVNGGYSGLRDVYIAHES-YDDVQQSFFLAETLKYLYLIFSDD-DLLPLEHWIFNTEAHPF 731

  Fly   679 PV 680
            |:
  Rat   732 PI 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ib	NP_651667.1	Glyco_hydro_47	242..680	CDD:279825	164/447 (37%)
Man1a1	XP_006256559.1	Glyco_hydro_47	295..733	CDD:279825	165/468 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54359
OrthoDB	1	1.010	-	-		D263455at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100239
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830