Protein Alignment alpha-Man-Ib and Man1b1

DIOPT Version :10

• Sequence 1: NP_651667.1
• Gene: alpha-Man-Ib / 43436
• FlyBaseID: FBgn0039634
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: NP_001025154.1
• Gene: Man1b1 / 227619
• MGIID: 2684954
• Length: 658
• Species: Mus musculus
• Alignment Length: 703
• Identity: 302/703 - (42%)
• Similarity: 418/703 - (59%)
• Gaps: 91/703 - (12%)

  Fly     7 ITLTLPPG-SAATTDERGRKSLRRAWNQLPRCQRNLIILGITGFCVTVLLC------LSGDQLLA 64
            |::||..| |...:..|.|:|..|.|.||.|.||| :||.:.||   ::||      .:.||..|
Mouse    16 ISVTLSLGESYDNSKSRRRRSCWRKWKQLSRLQRN-VILFVLGF---LILCGFLYSLHTADQWKA 76

  Fly    65 ASLKDVDT---KAEVAAYQMP-LPNPHHHPGVDKDVPKDTAAVPVPADKR-------APRVEAVS 118
            .|.:..:.   |.||    :| ||.|      .|:..:......:.:.||       .|.::
Mouse    77 LSGRPAEVEKMKQEV----LPVLPAP------QKESAEQEGFADILSQKRQRHFRRGPPHLQ--- 128

  Fly   119 DKFNELVAYGEANSAENVARLPETVAAEGLPQASAMAVALPPPDSNKEQD--IGGIDILNNVEEP 181
                              .|.|.||:.:|:            .|..||::  :|......|.:..
Mouse   129 ------------------IRPPNTVSKDGM------------QDDAKEREAALGKAQQEENTQRT 163

  Fly   182 VAQ---DPAEPLSEGEQLEQAIKNPLTLGGVSFKEHLKKIKPILAKGQHFH--GATNERQSAVVA 241
            |..   ...||       |||.:.|       :|.....|||::...:.:.  ...||||..|:.
Mouse   164 VISWRGAVIEP-------EQATELP-------YKRAEASIKPLVLASKIWKEPAPPNERQKGVIE 214

  Fly   242 AFKHSWAGYKKYAWGHDNLKPISQYSHEWFGLGLTIVDSLDTMYIMGLDDEFKEGRDWVEQSLRF 306
            ||.|:|.||:|:|||||.|||:|:...||||||||::|:||||:|:||..|||:.|.||.::|.|
Mouse   215 AFLHAWKGYQKFAWGHDELKPVSKTFSEWFGLGLTLIDALDTMWILGLKQEFKQARKWVSENLDF 279

  Fly   307 DTKRDVNLFEVTIRVLGGLLSAYHLSGDTMFLAKAAELGNRLLPAFQSPSNIPYSDVNLGDLSAH 371
            ....||||||.|||:||||||.||||||::||.||.:.|.||:|||.:||.|||||||:|...||
Mouse   280 QKNVDVNLFESTIRILGGLLSTYHLSGDSLFLTKAEDFGKRLMPAFTTPSKIPYSDVNIGTGFAH 344

  Fly   372 SPKWSPDSSTSEVTTIQLEFRDLSRSTNISIYEQVAHKVNEKVHDLE-KNHGLVPIFINANTGTF 435
            ||:|:.||:.:|||:||||||:|||.|.|..:::...:|.:.:|.|. |..||||:|||.|:|.|
Mouse   345 SPQWTSDSTVAEVTSIQLEFRELSRLTGIKKFQEAVEEVTKHIHSLSGKKDGLVPMFINTNSGLF 409

  Fly   436 RNYATISLGARGDSYYEYLLKQWIQTGRKDNDNLILDYMQAVDGVLTQLMRRTPREHWVYIGELI 500
            .:....:||||.|||||||||||||.|:|:. .|:.||::|::|:...|:|::......::|||.
Mouse   410 THPGVFTLGARADSYYEYLLKQWIQGGKKET-QLLEDYVKAIEGIKAHLLRQSQPRKLTFVGELA 473

  Fly   501 NGKDFKPKMDHLTCYLPGTLILGHQNGMPDSHLILARDLLDTCYQTYMMNPTHLAAEISYFALTE 565
            :|: |..|||||.|:|||||.||..:|:|..|:.|||.|::||||......|.|:.||::|.:..
Mouse   474 HGR-FSAKMDHLVCFLPGTLALGVHHGLPADHMDLARALMETCYQMNQQMETGLSPEIAHFNMYP 537

  Fly   566 K-DDQDIYVKPNDAHNLLRPEFVESLYYFYSITGNRTYQDMGWKIFQAFETHAKV-NAGYTSMGN 628
            : |.:|:.|||.|.|||||||.||||:|.|.:|.:|.|||.||:|.|:|..:.:| :.||:|:.|
Mouse   538 RADHKDVEVKPADRHNLLRPETVESLFYLYRVTRDRKYQDWGWEILQSFNKYTRVPSGGYSSINN 602

  Fly   629 VKNTQSTRLRDLMESFWMSETLKYFYLLFSDDRKEIDLEQWVFNSEGHPLPVY 681
            |:|:.....||.||||::.|||||.|||||||.:.:.|:..|||:|.||||::
Mouse   603 VQNSHKPEPRDKMESFFVGETLKYLYLLFSDDLELLSLDSCVFNTEAHPLPIW 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ib	NP_651667.1	Glyco_hydro_47	242..680	CDD:460241	238/440 (54%)
Man1b1	NP_001025154.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	123..142		6/51 (12%)
		Glyco_hydro_47	215..654	CDD:460241	238/440 (54%)