Protein Alignment alpha-Man-Ib and mans-3

DIOPT Version :10

• Sequence 1: NP_651667.1
• Gene: alpha-Man-Ib / 43436
• FlyBaseID: FBgn0039634
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: NP_508877.1
• Gene: mans-3 / 180787
• WormBaseID: WBGene00020197
• Length: 584
• Species: Caenorhabditis elegans
• Alignment Length: 561
• Identity: 252/561 - (44%)
• Similarity: 348/561 - (62%)
• Gaps: 40/561 - (7%)

  Fly   124 LVAYGEANSAENVARLPETVAAEGLPQASAMAVALPPPDSNKEQDIGGIDILNNVEEPVAQDPAE 188
            :.:.|||...:.:...||.:..|       ..:|......:||:....:..:::::..:.:|..:
 Worm    59 ICSQGEAKREQPIVENPEIIINE-------QVIAGQKTKHSKEESAENLKPVHDIDRQIVEDEMD 116

  Fly   189 PLSEGEQLEQAIKNPLTLGGVSFKEHLKKIKPILAKGQHFHGATNERQSAVVAAFKHSWAGYKKY 253
            ....|...|:.:|                          |.|.||:||.|||.||:|:|.|||||
 Worm   117 APETGGGNEKIVK--------------------------FTGPTNDRQKAVVKAFQHAWIGYKKY 155

  Fly   254 AWGHDNLKPISQYSHEWFGLGLTIVDSLDTMYIMGLDDEFKEGRDWVEQSLRFDTKRDVNLFEVT 318
            |||||.|||:|:...:||..||||||.|||..||||:||..|..:|::.:|.|:..|.||.||.|
 Worm   156 AWGHDTLKPVSKSYSDWFDTGLTIVDGLDTAIIMGLEDEATEATEWIQNTLTFEKDRMVNFFECT 220

  Fly   319 IRVLGGLLSAYHLSGDTMFLAKAAELGNRLLPAFQSPSNIPYSDVNLGDLSAHSPKWSPDSSTSE 383
            ||||||::||:||:|..|||.|:.:||:|||.||:|||.||||||||...:|.:|:|..|||.||
 Worm   221 IRVLGGMMSAFHLTGKKMFLEKSVDLGDRLLSAFKSPSPIPYSDVNLLKRTATNPQWGADSSLSE 285

  Fly   384 VTTIQLEFRDLSRSTNISIYEQVAHKVNEKVHDL--EKNHGLVPIFINANTGTFRNYATISLGAR 446
            |||:|||:|.|||::..|.||.:...|.:.:|.:  |.:.||..:|||||||.|:..:||:.|||
 Worm   286 VTTVQLEYRALSRASGNSTYEDLTFNVFKHIHKIGCETHEGLCGMFINANTGNFKKDSTITFGAR 350

  Fly   447 GDSYYEYLLKQWIQTGRKDNDNLILDYMQAVDGVLTQLMRRTPREHWVYIGELINGKDFKPKMDH 511
            .||:||||.||||||| |..|.|..||.:|:..:...|.|.:......:||||::|:.:.|||||
 Worm   351 SDSFYEYLFKQWIQTG-KTIDWLKEDYGKAMKAMEKYLYRNSKPNKMFFIGELLSGQTYSPKMDH 414

  Fly   512 LTCYLPGTLILGHQNGMPDSHLILARDLLDTCYQTYMMNPTHLAAEISYFALTEKDDQDIYVKPN 576
            |.|::.|||..|.|:|.|..||.:|..:.:||:..| .|||.|..||::|.:. ...:|:||||.
 Worm   415 LVCFIAGTLSQGSQHGFPRKHLDMAEKIGETCHNMY-DNPTGLGPEIAHFNMI-PGKEDLYVKPL 477

  Fly   577 DAHNLLRPEFVESLYYFYSITGNRTYQDMGWKIFQAFETHAKV-NAGYTSMGNVKNTQSTRLRDL 640
            |||.|||||.:|:.:|.|..||::.||:.||..|||.|.:|:: ..||:|:.|||.. :.|.||.
 Worm   478 DAHCLLRPEAIEAWFYLYRFTGDKKYQEWGWSAFQAIEKYARIPTGGYSSISNVKQI-NVRFRDS 541

  Fly   641 MESFWMSETLKYFYLLFSDDRKEIDLEQWVFNSEGHPLPVY 681
            ||||.:.||.||.|||..||:..:.|::|||.:||||||:|
 Worm   542 MESFLLGETFKYLYLLLGDDQTVLPLDKWVFTTEGHPLPIY 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ib	NP_651667.1	Glyco_hydro_47	242..680	CDD:460241	228/440 (52%)
mans-3	NP_508877.1	Glyco_hydro_47	144..581	CDD:460241	228/440 (52%)