Protein Alignment alpha-Man-Ib and mans-2

DIOPT Version :10

• Sequence 1: NP_651667.1
• Gene: alpha-Man-Ib / 43436
• FlyBaseID: FBgn0039634
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: NP_001256389.1
• Gene: mans-2 / 179642
• WormBaseID: WBGene00008258
• Length: 590
• Species: Caenorhabditis elegans
• Alignment Length: 667
• Identity: 208/667 - (31%)
• Similarity: 324/667 - (48%)
• Gaps: 120/667 - (17%)

  Fly    44 LGITGFCVTVLLCLSGDQLLAASLKDVDTKAEVAAYQMPLPNPHHHPGVDKDVPKDTAAVPVPAD 108
            |.|...|...|||                   |..|.......|:               .|...
 Worm    11 LAILAACFIFLLC-------------------VVCYFSASSESHN---------------AVVVG 41

  Fly   109 KRAPRVEAVSDKFNELVAYGEANS---AENVARLPETVAAEGLPQASAMAVALPPPDSNKEQDIG 170
            :||....||.|..|..:| .|.::   |:.|.::...|:.|.:.......|...||.
 Worm    42 ERARGHIAVRDVENRHLA-EEKHAVIHAKTVGKIERVVSQEKVEILRPARVESKPPG-------- 97

  Fly   171 GIDILNNVEEPVAQDPAE------PLSEGEQLEQAIKNPLTLGGVSFKEHLKKIKPILAKGQHFH 229
                     |..:.:|.|      |:...|.||:.|               .||        |:.
 Worm    98 ---------EKTSTEPEETGVGKAPIQTSEGLEKLI---------------GKI--------HYE 130

  Fly   230 GATNE---RQSAVVAAFKHSWAGYKKYAWGHDNLKPISQ--YSHEWFG---LGLTIVDSLDTMYI 286
            ....|   |:..|.....|:|.|||.|:||.:.|:|:|:  .|...||   :..||||:.||::|
 Worm   131 NKDEENDLRRQKVKEMMIHAWEGYKNYSWGANELRPMSKKPNSQNIFGGSQMPATIVDAADTLFI 195

  Fly   287 MGLDDEFKEGRDWVEQSLRF-DTKRDVNLFEVTIRVLGGLLSAYHLSGDTMFLAKAAELGNRLLP 350
            |.|.|::||.||::|.:... .:...:::||.|||.||||||.|.|:.::.::.||.|:|..|||
 Worm   196 MDLKDKYKEARDYIENNFSMAKSTSTLSVFETTIRFLGGLLSLYALTQESFYIEKAREVGEALLP 260

  Fly   351 AFQSPSNIPYSDVNLGDLSAHSPKWS--PDSSTSEVTTIQLEFRDLSRSTNISIYEQVAHKVNEK 413
            ||.:||.||.|::::....|.:..|:  ..|..||:.::.|||..|||.:|..|:|:...||.:.
 Worm   261 AFNTPSGIPKSNLDVASKHASNYGWANGGQSILSEIGSLHLEFLYLSRISNAPIFEKKVKKVRDA 325

  Fly   414 VHDLEKNHGLVPIFINANTGTFRNYATISLGARGDSYYEYLLKQWIQTGRKDND--NLILDYMQA 476
            :...||.:||...:||.:||.|.. :.:||||.|||:||||:|.::|:...|..  |:   |...
 Worm   326 LEKAEKPNGLYSNYINPDTGKFTG-SHMSLGALGDSFYEYLIKSYVQSNYTDTQAKNM---YWDV 386

  Fly   477 VDGVLTQLMRRTPREHWVYIGELINGKDFKPKMDHLTCYLPGTLILGHQNGMPDSH----LILAR 537
            .|.:...:::.:.:.:..|..||.||: .:.||.||.|::||...|...|...:..    :.||.
 Worm   387 SDAIQKHMIKVSKQSNLTYTVELNNGQ-AQHKMGHLACFVPGMFALQAINEDTEEEKLRIMTLAE 450

  Fly   538 DLLDTCYQTYMMNPTHLAAEISYF----ALTEKDDQDIYVKPNDAHNLLRPEFVESLYYFYSITG 598
            :|..||:::|:.:.||:..|:.||    ..|.|..::.|::        |||.:|..:|.:.:||
 Worm   451 ELAKTCHESYIRSETHIGPEMFYFNERDEATSKHSENGYIQ--------RPEVIEGWFYLWRLTG 507

  Fly   599 NRTYQDMGWKIFQAFETHAKVNAGYTSMGNVKNTQSTRLRDLMESFWMSETLKYFYLLFSDDRKE 663
            ...|:|..|...||.|.:.:|::|:|.:.||.|.::.| .|:|:||:::|.|||.||.|:|: ..
 Worm   508 KTMYRDWVWDAVQAIEKYCRVDSGFTGLQNVYNPKAGR-EDVMQSFFLAEFLKYAYLTFADE-SL 570

  Fly   664 IDLEQWVFNSEGHPLPV 680
            |.|::||||:|.||:||
 Worm   571 ISLDKWVFNTEAHPVPV 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ib	NP_651667.1	Glyco_hydro_47	242..680	CDD:460241	167/455 (37%)
mans-2	NP_001256389.1	LanC_like	103..587	CDD:471159	180/521 (35%)