Protein Alignment alpha-Man-Ib and mans-4

DIOPT Version :10

• Sequence 1: NP_651667.1
• Gene: alpha-Man-Ib / 43436
• FlyBaseID: FBgn0039634
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: NP_001255361.1
• Gene: mans-4 / 177726
• WormBaseID: WBGene00013881
• Length: 532
• Species: Caenorhabditis elegans
• Alignment Length: 478
• Identity: 230/478 - (48%)
• Similarity: 325/478 - (67%)
• Gaps: 25/478 - (5%)

  Fly   215 LKKIKPILAKGQHFHGATNERQSAVVAAFKHSWAGYKKYAWGHDNLKPISQYSHEWFGLGLTIVD 279
            ||:..|:      |.|.|||||.|:|.||:|:|:||||||||||.|:|:|:...:.|||||||:|
 Worm    68 LKRAPPV------FQGPTNERQKAIVRAFQHAWSGYKKYAWGHDELRPVSKRFDDSFGLGLTIID 126

  Fly   280 SLDTMYIMGLDDEFKEGRDWVEQSLRFDTKRDVNLFEVTIRVLGGLLSAYHLSGDTMFLAKAAEL 344
            ||||..||||::|.::|.:|:.::|.....|.||:||.||||||||||.|||:|:...|.||.:|
 Worm   127 SLDTAIIMGLEEETRDGVEWIRENLNVSPARSVNVFETTIRVLGGLLSGYHLTGEEALLEKATQL 191

  Fly   345 GNRLLPAF-QSPSNIPYSDVNLGDLSAHSPKWSPD-SSTSEVTTIQLEFRDLSRSTNISIYEQVA 407
            |:.|:.|| :|.|.||.|||||.:.:|.||  :.| ||.:|.||:|||||||:..|....||.||
 Worm   192 GDNLIKAFTKSSSLIPKSDVNLDNGNACSP--NRDLSSLAEATTLQLEFRDLTALTGDQKYEDVA 254

  Fly   408 HKVNEKVHDL--EKNHGLVPIFINANTGTFRNYATISLGARGDSYYEYLLKQWIQTGRKDNDNLI 470
            ...:|.||::  :|..||.|.:|:.. |.|:. ::|:||||.|||||||:|||:|| :|..|.|.
 Worm   255 FGASEHVHNVGCKKMDGLCPFYIDGK-GEFKK-SSITLGARADSYYEYLIKQWLQT-KKSIDWLR 316

  Fly   471 LDYMQAVDGVLTQLMRRT-PREHWVYIGELINGKDFKPKMDHLTCYLPGTLILGHQNGM--PDSH 532
            .|::|::..:...|.|:: |...| ::||:.....|.||||||.|:|.|:|:|.|.||:  .:.|
 Worm   317 DDFIQSIAAMKKHLYRQSQPNSIW-FLGEITELAQFYPKMDHLVCFLSGSLVLSHLNGLDHDNEH 380

  Fly   533 LILARDLLDTCYQTYMMNPTHLAAEISYFALTEKDDQ---DIYVKPNDAHNLLRPEFVESLYYFY 594
            |.:|:::.:.|::.| .|||.|..||.:|.:.:..|.   |.|||..|||:|||||.:|:.:|.|
 Worm   381 LEMAKNIGNVCHKMY-ENPTGLGPEIIHFNMEDSSDMTQADTYVKNLDAHSLLRPEAIEAWFYLY 444

  Fly   595 SITGNRTYQDMGWKIFQAFETHAKV-NAGYTSMGNVKNTQSTRLRDLMESFWMSETLKYFYLLFS 658
            .:|.::.||:.|||.|::.|.:||| ..||:|:.||...:..| ||.||||:::|||||.|||.:
 Worm   445 RVTKDKKYQEWGWKAFESIEKYAKVETGGYSSIDNVLRKKIKR-RDKMESFFLAETLKYLYLLMA 508

  Fly   659 DDRKEIDLEQWVFNSEGHPLPVY 681
            ||::.:.|::||.|:|.||||:|
 Worm   509 DDQEILPLDRWVLNTEAHPLPIY 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ib	NP_651667.1	Glyco_hydro_47	242..680	CDD:460241	216/448 (48%)
mans-4	NP_001255361.1	Glyco_hydro_47	89..530	CDD:460241	216/448 (48%)