Protein Alignment alpha-Man-Ib and Edem2

DIOPT Version :10

• Sequence 1: NP_651667.1
• Gene: alpha-Man-Ib / 43436
• FlyBaseID: FBgn0039634
• Length: 685
• Species: Drosophila melanogaster
• Sequence 2: XP_314865.4
• Gene: Edem2 / 1275602
• VectorBaseID: AGAMI1_014653
• Length: 806
• Species: Anopheles gambiae
• Alignment Length: 486
• Identity: 144/486 - (29%)
• Similarity: 234/486 - (48%)
• Gaps: 77/486 - (15%)

  Fly   233 NERQSAVVAAFKHSWAGYKKYAWGHDNLKPIS---QYS---------HEWFG-LGLTIVDSLDTM 284
            ||.:......|.|::..|...|:..|.|.|:|   :|.         .:..| ..:|:||:|||:
Mosquito    60 NELKEEAREMFYHAYRAYMDNAYPADELMPLSCAGRYRGVTPSRGDLDDTLGNFSMTLVDTLDTL 124

  Fly   285 YIMGLDDEFKEGRDWVEQSLRFDTKRDVNLFEVTIRVLGGLLSAYHLS------GDTM------F 337
            .::|..:||:.....|.:.::||....|::||..||::|||||.:.|:      .|.|      .
Mosquito   125 VVLGDLEEFEHAVKLVIKDVKFDNDIIVSVFETNIRMIGGLLSGHILAEYVQKQADVMTWYRGEL 189

  Fly   338 LAKAAELGNRLLPAFQSPSNIPYSDVNL-GDLSAHSPKWSPDSSTSEVTTIQLEFRDLSRSTNIS 401
            |..|.:||.||||||.:.:.||::.||| ..:...:.:.|.::.|:...||.|||..|||.:...
Mosquito   190 LEMAKDLGYRLLPAFNTSTGIPHARVNLKHGMKVEALRHSRETCTACAGTILLEFAALSRLSGEP 254

  Fly   402 IYEQVAHKVNEKVHDL-EKNHGLVPIFINANTGTFRNYATISLGARGDSYYEYLLKQWIQTGRKD 465
            |:|..||...:.:..: .::..|:...:|.::|.:....: .:||..||||||.||.:|..|.:
Mosquito   255 IFEVKAHAAMDALWKMRHRSSELMGTVLNVHSGDWIRRES-GVGAGIDSYYEYCLKSYILLGDE- 317

  Fly   466 NDNLILDYMQAVDGVLTQLMRRTPREHWVYIGE---LINGKDFKPK------MDHLTCYLPGTLI 521
                  .|:...:.....:|:        ||.:   |::.:..:|.      ||.|..:.||..:
Mosquito   318 ------RYLARFNRHYHAIMK--------YISQGPMLLDVQMHRPHTKTRNFMDALLAFWPGLQV 368

  Fly   522 L-GHQNGMPDSHLILARDLLDTCYQTYMMNPTHLAAEISYFALTEKDDQDIYVKPNDAHNLLRPE 585
            | |.......:|.:|        ||...|: |.:....::         |..|.....|  ||||
Mosquito   369 LSGDLKPAVQTHEML--------YQVMQMH-TFIPEAFTF---------DFQVHWGQHH--LRPE 413

  Fly   586 FVESLYYFYSITGNRTYQDMGWKIFQAFETHAKVNAGYTSMGNVKNTQSTRLRDLMESFWMSETL 650
            |:||.|:.|..||:..|...|.|..:|.:.||:|..||.::.:|:   :.:..|.|:|:.:|||.
Mosquito   414 FIESTYFLYRATGDHYYLHAGKKALKALQKHARVPCGYAAVNDVR---TGKHEDRMDSYVLSETF 475

  Fly   651 KYFYLLFSDDRKEI-DLEQWVFNSEGHPLPV 680
            ||.:|||||....| ::|.::|.:|.|.||:
Mosquito   476 KYLFLLFSDPADLILNIEDFIFTTEAHLLPL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Man-Ib	NP_651667.1	Glyco_hydro_47	242..680	CDD:460241	141/475 (30%)
Edem2	XP_314865.4	None